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Chiral synthesis of LSD1 inhibitor GSK2879552 enabled by directed evolution of an imine reductase
Schober, Markus, MacDermaid, Chris, Ollis, Anne A., Chang, Sandy, Khan, Diluar, Hosford, Joseph, Latham, Jonathan, Ihnken, Leigh Anne F., Brown, Murray J. B., Fuerst, Douglas, Sanganee, Mahesh J., RoiVolume:
2
Journal:
Nature Catalysis
DOI:
10.1038/s41929-019-0341-4
Date:
October, 2019
File:
PDF, 1.29 MB
2019