Development of novel oxotriazinoindole inhibitors of aldose...

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Development of novel oxotriazinoindole inhibitors of aldose reductase: isosteric sulfur/oxygen replacement in the thioxotriazinoindole cemtirestat markedly improved inhibition selectivity

Hlavac, Matus, Kovacikova, Lucia, Soltesova Prnova, Marta, Šramel, Peter, Addova, Gabriela, Majekova, Magdalena, Hanquet, Gilles, Bohac, Andrej, Stefek, Milan
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Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b01747
Date:
December, 2019
File:
PDF, 772 KB
2019
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