Different roles of human cytochrome P450 2C9 and 3A enzymes in diclofenac 4'- and 5-hydroxylations mediated by metabolically inactivated human hepatocytes in previously transplanted chimeric mice
Miura, Tomonori, Uehara, Shotaro, Shimizu, Makiko, Murayama, Norie, Utoh, Masahiro, Suemizu, Hiroshi, Yamazaki, HiroshiJournal:
Chemical Research in Toxicology
DOI:
10.1021/acs.chemrestox.9b00446
Date:
December, 2019
File:
PDF, 265 KB
2019