AIP Conference Proceedings [AIP Publishing PROCEEDINGS OF THE 45TH INTERNATIONAL CONFERENCE ON APPLICATION OF MATHEMATICS IN ENGINEERING AND ECONOMICS (AMEE’19) - Sozopol, Bulgaria (07–13 June 2019)] PROCEEDINGS OF THE 45TH INTERNATIONAL CONFERENCE ON APPLICATION OF MATHEMATICS IN ENGINEERING AND ECONOMICS (AMEE’19) - Conceptual model of integrated approach for in silico knowledge data discovery for breast cancer diagnostics and precision therapy