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Discovery and Characterization of Fluorine-Substituted Diarylpyrimidines Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel
Kang, Dongwei, Ruiz, F. Xavier, Feng, Da, Pilch, Alyssa, Zhao, Tong, Wei, Fenju, Wang, Zhao, Sun, Yanying, Fang, Zengjun, De Clercq, Erik, Pannecouque, Christophe, Arnold, Eddy, Zhan, Peng, Liu, XinyoJournal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b01769
Date:
January, 2020
File:
PDF, 644 KB
2020