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Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity
Grandjean, Jean-Marc M., Jiu, Alexander Y., West, John W., Aoyagi, Atsushi, Droege, Daniel G., Elepano, Manuel, Hirasawa, Makoto, Hirouchi, Masakazu, Murakami, Ryo, Lee, Joanne, Sasaki, Koji, Hirano,Language:
english
Journal:
ACS Medicinal Chemistry Letters
DOI:
10.1021/acsmedchemlett.9b00480
Date:
January, 2020
File:
PDF, 1.33 MB
english, 2020