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The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer
Luker, Andrea J., Graham, Laura J., Smith, Timothy M., Camarena, Carmen, Zellner, Matt P., Gilmer, Jamie-Jean S., Damle, Sheela R., Conrad, Daniel H., Bear, Harry D., Martin, Rebecca K.Volume:
21
Journal:
BMC Immunology
DOI:
10.1186/s12865-020-0337-5
Date:
December, 2020
File:
PDF, 3.46 MB
2020