A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects
Zuo, Erwei, Sun, Yidi, Yuan, Tanglong, He, Bingbing, Zhou, Changyang, Ying, Wenqin, Liu, Jing, Wei, Wu, Zeng, Rong, Li, Yixue, Yang, HuiJournal:
Nature Methods
DOI:
10.1038/s41592-020-0832-x
Date:
May, 2020
File:
PDF, 10.67 MB
2020
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