Synthetic flavonoid derivatives targeting the glycogen...

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Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors

Chetter, Ben A., Kyriakis, Efthimios, Barr, Daniel, Karra, Aikaterini G., Katsidou, Elisabeth, Koulas, Symeon M., Skamnaki, Vassiliki T., Snape, Timothy J., Psarra, Anna-Maria G., Leonidas, Demetres D
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Journal:
Bioorganic Chemistry
DOI:
10.1016/j.bioorg.2020.104003
Date:
June, 2020
File:
PDF, 3.63 MB
2020
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