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Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development that informs Chemically Reactive Metabolite formation and Potential for Drug Induced Liver Injury
Monroe, James J, Tanis, Keith Q, Podtelezhnikov, Alexei A, Nguyen, Truyen, Mahotka, Sam, Lynch, Donna, Evers, Raymond, Palamanda, Jairam, Miller, Randy, Pippert, Todd, Cabalu, Tammie, Johnson, TimothyJournal:
Toxicological Sciences
DOI:
10.1093/toxsci/kfaa088
Date:
June, 2020
File:
PDF, 2.80 MB
2020