Shortening the sgRNA-DNA interface enables SpCas9 and eSpCas9(1.1) to nick the target DNA strand
Fan, Rong, Chai, Zhuangzhuang, Xing, Sinian, Chen, Kunling, Qiu, Fengti, Chai, Tuanyao, Qiu, Jin-Long, Zhang, Zhengbin, Zhang, Huawei, Gao, CaixiaJournal:
Science China Life Sciences
DOI:
10.1007/s11427-020-1722-0
Date:
June, 2020
File:
PDF, 2.17 MB
2020