Mechanistic Study of Potent Fluorinated EGFR Kinase...

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Journal of Physical Chemistry B 2020 / 06

Mechanistic Study of Potent Fluorinated EGFR Kinase Inhibitors with a Quinazoline Scaffold against L858R/T790M/C797S Resistance Mutation: Unveiling the Fluorine Substituent Cooperativity Effect on the Inhibitory Activity

Akher, Farideh Badichi, Farrokhzadeh, Abdolkarim, Ravenscroft, Neil, Kuttel, Michelle M.
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Journal:
The Journal of Physical Chemistry B
DOI:
10.1021/acs.jpcb.0c03440
Date:
June, 2020
File:
PDF, 3.83 MB
2020
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