Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile
Bigi-Botterill, Simone V., Ivetac, Anthony, Bradshaw, Erica L., Cole, Derek, Dougan, Douglas R., Ermolieff, Jacques, Halkowycz, Petro, Johnson, Ben, McBride, Christopher, Pickens, Jason, Sabat, Mark,Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2020.127405
Date:
July, 2020
File:
PDF, 866 KB
2020
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