Structure-based design, synthesis and bioactivity...

European Journal of Medicinal Chemistry 2020 / 10 Vol. 203

Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells

Che, Jinxin, Huang, Feng, Zhang, Mengmeng, Xu, Gaoya, Qu, Bingxue, Gao, Jian, Chen, Binhui, Zhang, Jianjun, Ying, Huazhou, Hu, Yongzhou, Hu, Xiaobei, Zhou, Yubo, Gao, Anhui, Li, Jia, Dong, Xiaowu
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Volume:
203
Journal:
European Journal of Medicinal Chemistry
DOI:
10.1016/j.ejmech.2020.112491
Date:
October, 2020
File:
PDF, 950 KB
2020
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