Structure of Human Phosphodiesterase 5A1 Complexed with Avanafil Reveals Molecular Basis of Isoform Selectivity and Guide-lines for Targeting α-Helix Backbone Oxygen by Halogen Bonding
Hsieh, Chao-Ming, Chen, Chun-Yi, Chern, Ji-Wang, Chan, Nei-LiJournal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.0c00853
Date:
July, 2020
File:
PDF, 1.11 MB
2020