Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA
Liu, Mu-Sen, Gong, Shanzhong, Yu, Helen-Hong, Jung, Kyungseok, Johnson, Kenneth A., Taylor, David W.Volume:
11
Journal:
Nature Communications
DOI:
10.1038/s41467-020-17411-1
Date:
December, 2020
File:
PDF, 2.51 MB
2020