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Stepwise Design of γ-Secretase Modulators with Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring Bioisostere
Rodriguez Sarmiento, Rosa Maria, Bissantz, Caterina, Bylund, Johan, Limberg, Anja, Neidhart, Werner, Jakob-Roetne, Roland, Wang, Lisha, Baumann, KarlheinzJournal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.0c00909
Date:
July, 2020
File:
PDF, 1.24 MB
2020