Discovery of 4-methyl-N-(4-((4-methylpiperazin-...

Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant

Li, Xiaoyang, Su, Jingyi, Yang, Yanru, Lian, Wenhua, Deng, Zhou, Yang, Zaiyou, Chen, Guyue, Zhang, Baoding, Dong, Chao, Liu, Xueyan, Li, Li, Wang, Zheng, Hu, Zhiyu, Xu, Qingyan, Deng, Xianming
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Volume:
207
Journal:
European Journal of Medicinal Chemistry
DOI:
10.1016/j.ejmech.2020.112755
Date:
December, 2020
File:
PDF, 5.06 MB
2020
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