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Balancing the Affinity and Pharmacokinetics of Antibodies by Modulating the Size of Charge Patches on Complementarity-Determining Regions
Sun, Yue, Cai, Hao, Hu, Zhilan, Boswell, C. Andrew, Diao, Jinpian, Li, Charlene, Zhang, Liangyi, Shen, Amy, Teske, Christopher A., Zhang, Boyan, Kamath, Amrita V., Jiang, GuoyingJournal:
Journal of Pharmaceutical Sciences
DOI:
10.1016/j.xphs.2020.09.003
Date:
September, 2020
File:
PDF, 1.10 MB
2020