Discovery of an orally active VHL-recruiting PROTAC that...

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Acta Pharmaceutica Sinica B 2020 / 11

Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo

Luo, Guoshun, Li, Zhenbang, Lin, Xin, Li, Xinyu, Chen, Yu, Xi, Kun, Xiao, Maoxu, Wei, Hanlin, Zhu, Lizhe, Xiang, Hua
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Journal:
Acta Pharmaceutica Sinica B
DOI:
10.1016/j.apsb.2020.11.001
Date:
November, 2020
File:
PDF, 1.45 MB
2020
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