The chemotherapeutic agent CX-5461 irreversibly blocks RNA...

NAR Cancer 2020 / 11 Vol. 2; Iss. 4

The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability

Mars, Jean-Clément, Tremblay, Michel G, Valere, Mélissa, Sibai, Dany S, Sabourin-Felix, Marianne, Lessard, Frédéric, Moss, Tom
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Volume:
2
Journal:
NAR Cancer
DOI:
10.1093/narcan/zcaa032
Date:
November, 2020
File:
PDF, 3.29 MB
2020
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