Volume 20; Issue 1

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Investigational New Drugs
Volume 20; Issue 1

Investigational New Drugs

Volume 20; Issue 1

1

Partial Circumvention of P-Glycoprotein-Mediated Multidrug Resistance by Doxorubicin-14-O-Hemiadipate

Olga V. Leontieva, Maria N. Preobrazhenskaya, Ralph J. Bernacki

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 1.30 MB

english, 2002

2

Chemotherapy-Induced Palmar-Plantar Erythrodysesthesia Syndrome – Recall Following Different Chemotherapy Agents

Yuk Fung Hui, Francis J. Giles, Jorge E. Cortes

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 61 KB

english, 2002

3

Phase II Trial of Pegylated-Liposomal Doxorubicin (Doxil™) in Renal Cell Cancer

Keith M. Skubitz

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 50 KB

english, 2002

4

Phase I Clinical Trial of 5-Fluoro-Pyrimidinone (5FP), an Oral Prodrug of 5-Fluorouracil (5FU)

Patricia M. LoRusso, Sucharu Prakash, Antoinette Wozniak, Lawrence Flaherty, Mark Zalupski, Anthony Shields, Howard Sands, Ralph Parchment, Bhaskara Jasti

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

5

A Phase II Trial of Bryostatin-1 in Patients with Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck

David G. Pfister, John McCaffrey, Andrew J. Zahalsky, Gary K. Schwartz, Eric Lis, William Gerald, Andrew Huvos, Jatin Shah, Dennis Kraus, Ashok Shaha, Bhuvanesh Singh, Suzanne Wolden, Michael Zelefsky

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

6

Population Pharmacokinetic and Dynamic Analysis of the Topoisomerase I Inhibitor Lurtotecan in Phase II Studies

J.H.M. Schellens, B. Heinrich, M. Lehnert, M.E. Gore, S.B. Kaye, P. Dombernowsky, R. Paridaens, A.T. van Oosterom, J. Verweij, W.J. Loos, H. Calvert, N. Pavlidis, H. Cortes-Funes, J. Wanders, M. Roelv

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 112 KB

english, 2002

7

Lack ofin Vitro–in VivoCorrelation of a Novel Investigational Anticancer Agent, SH 30

Srinivasu Poondru, Ralph E. Parchment, Vivek Purohit, Patricia LoRusso, Jerome P. Horwitz, Stuart T. Hazeldine, Lisa Polin, Thomas Corbett, Bhaskara R. Jasti

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 163 KB

english, 2002

8

Anticancer Activity and Protein Phosphatase 1 and 2A Inhibition of a New Generation of Cantharidin Analogues

Jennette A. Sakoff, Stephen P. Ackland, Monique L. Baldwin, Mirella A. Keane, Adam McCluskey

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 175 KB

english, 2002

9

Phase II Trial of Topotecan by Continuous Infusion in Patients with Advanced Soft Tissue Sarcomas, a SWOG Study

G. Thomas Budd, Cathryn Rankin, Laura F. Hutchins, Lucas Wong, Paul J. Petruska, Karen Antman

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 50 KB

english, 2002

10

Preclinical Efficacy Evaluations of XK-469: Dose Schedule, Route and Cross-Resistance Behavior in Tumor Bearing Mice

Lisa Polin, Kathryn White, Juiwanna Kushner, Jennifer Paluch, Chiab Simpson, Susan Pugh, Matthew K. Edelstein, Stuart Hazeldine, Joseph Fontana, Patricia LoRusso, Jerome P. Horwitz, Thomas H. Corbett

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 309 KB

english, 2002

11

Phase I Study of JM-216 (an Oral Platinum Analogue) in Combination with Paclitaxel in Patients with Advanced Malignancies

Suzanne Jones, John Hainsworth, Howard A. Burris, Dana Thompson, Eric Raefsky, Valerie Johnson, Sharon Calvert, Cecile Bulanhagui, David Lebwohl, F. Anthony Greco

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

12

Phase II Trial of Docetaxel Chemotherapy in Patients with Incurable Adenocarcinoma of the Esophagus

Elisabeth I. Heath, Susan Urba, John Marshall, Steven Piantadosi, Arlene A. Forastiere

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 58 KB

english, 2002

13

A Phase II Trial of Pyrazine Diazohydroxide in Patients with Disseminated Malignant Melanoma and no Prior Chemotherapy – Southwest Oncology Group Study

Robert P. Whitehead, Joseph M. Unger, Lawrence E. Flaherty, Eric H. Kraut, Glenn M. Mills, Catherine E. Klein, Robert A. Chapman, Gary C. Doolittle, Neel Hammond, Vernon K. Sondak

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 78 KB

english, 2002

14

Phase II Trial of Amonafide in Central Nervous System Tumors: A Southwest Oncology Group Study

Sarah A. Taylor, Cathryn Rankin, Jeannette J. Townsend, Johnny B. Craig, Ralph B. Vance, Dilip L. Solank, Thomas D. Brown, Kurt Jaeckle

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 44 KB

english, 2002

15

Phase I/II Study of Gemcitabine plus Vinorelbine in Non-Small Cell Lung Cancer

Emilio Esteban, Joaquin Fra, Norberto Corral, Miguel Valle, Juan Carrasco, Marian Sala, Javier Puerta, Enrique Estrada, Isabel Palacio, Jose Maria Vieitez, Jose Maria Buesa, Angel Jimenez Lacave

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 91 KB

english, 2002

16

The Evaluation of Gemcitabine in Resistant or Relapsing Multiple Myeloma, Phase II: a Southwest Oncology Group Study

James K. Weick, John J. Crowley, Mohamed A. Hussein, Dennis F. Moore, Bart Barlogie

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 61 KB

english, 2002

17

Raltitrexed (Tomudex) Administration in Patients Failing Multiple Prior Chemotherapy Regimens in Advanced Colorectal Cancer: a Pilot Study

N. Tsavaris, C. Kosmas, M. Vadiaka, A. Kontos, M. Fotia, A. Angelopoulou, N. Vrizidis, M. Soulla, S. Sougioultzis, Ch. Koufos

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

18

Instructions for Authors

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 50 KB

english, 2002