Volume 22; Issue 2

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Investigational New Drugs
Volume 22; Issue 2

Investigational New Drugs

Volume 22; Issue 2

1

Resveratrol Antagonizes EGFR-Dependent Erk1/2 Activation in Human Androgen-Independent Prostate Cancer Cells with Associated Isozyme-Selective PKCα Inhibition

Jubilee R. Stewart, Catherine A. O'Brian

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

2

The New Isothiocyanate 4-(Methylthio)Butylisothiocyanate Selectively Affects Cell-Cycle Progression and Apoptosis Induction of Human Leukemia Cells

Carmela Fimognari, Michael Nüsse, Renato Iori, Giorgio Cantelli-Forti, Patrizia Hrelia

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

3

Phase I Trial of the Polyamine Analog N1,N14-Diethylhomospermine (DEHSPM) in Patients with Advanced Solid Tumors

George Wilding, David King, Kendra Tutsch, Marcia Pomplun, Chris Feierabend, Dona Alberti, Rhoda Arzoomanian

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 125 KB

english, 2004

4

A Phase I Trial of Daily Oral 4′-N-Benzoyl-Staurosporine in Combination with Protracted Continuous Infusion 5-Fluorouracil in Patients with Advanced Solid Malignancies

Joseph P. Eder, Rocio Garcia-Carbonero, Jeffrey W. Clark, Jeffrey G. Supko, Thomas A. Puchalski, David P. Ryan, Pamela Deluca, Antoinette Wozniak, Angela Campbell, John Rothermel, Patricia LoRusso

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

5

Pharmacokinetic Drug–Drug Interaction of the Novel Anticancer Agent E7070 and Acenocoumarol

H.J.G. Desirée van den Bongard, Rolf W. Sparidans, David J.P. Critchley, Jos H. Beijnen, Jan H.M. Schellens

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 84 KB

english, 2004

6

Phase I and Pharmacokinetic Study of Fostriecin given as an Intravenous Bolus Daily for Five Consecutive Days

Lyly H. Lê, Charles Erlichman, Linda Pillon, Jake J. Thiessen, Andrew Day, Nancy Wainman, Elizabeth A. Eisenhauer, Malcolm J. Moore

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 108 KB

english, 2004

7

Phase II Trial of Intra-Arterial Chemotherapy using a Novel Lipophilic Platinum Derivative (SM-11355) in Patients with Hepatocellular Carcinoma

Takuji Okusaka, Shuichi Okada, Toshio Nakanishi, Shigetoshi Fujiyama, Yasuhiko Kubo

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 250 KB

english, 2004

8

Phase II Trial of Temozolomide in Patients with Cisplatin-Refractory Germ Cell Tumors

G. Varuni Kondagunta, Jennifer Bacik, Lawrence Schwartz, Joel Sheinfeld, Dean Bajorin, Jacqueline Vuky, Stephanie Marion, Madhu Mazumdar, George J. Bosl, Robert J. Motzer

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 41 KB

english, 2004

9

Phase II Study of CI-958 in Patients with Hormone Refractory Prostate Carcinoma

J. Philip Kuebler, Timothy Moore, James Pritchard, Eric Kraut

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 44 KB

english, 2004

10

A Novel Combination of Cisplatin, Irinotecan, and Capecitabine in Patients with Advanced Cancer

Michael Jefford, Michael Michael, Mark A. Rosenthal, Ian D. Davis, Michael Green, Bev McClure, Jennifer Smith, Brigid Waite, John Zalcberg

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 71 KB

english, 2004

11

Weekly Gemcitabine for the Treatment of Biliary Tract and Gallbladder Cancer

Nikolas Tsavaris, Christos Kosmas, Panagiotis Gouveris, Kostadinos Gennatas, Aris Polyzos, Despina Mouratidou, Heracles Tsipras, Helias Margaris, George Papastratis, Evanthia Tzima, Nikitas Papadoniou

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 61 KB

english, 2004