Volume 24; Issue 4

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Investigational New Drugs
Volume 24; Issue 4

Investigational New Drugs

Volume 24; Issue 4

1

A phase I Study with oral SU5416 in patients with advanced solid tumors: A drug inducing its clearance

Marc Salzberg, Miklos Pless, Christoph Rochlitz, Klara Ambrus, Paul Scigalla, Richard Herrmann

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 154 KB

english, 2006

2

A phase I study of flavopiridol and docetaxel

Basil F. El-Rayes, Shirish Gadgeel, Ralph Parchment, Patricia Lorusso, Philip A. Philip

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006

3

Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: A Southwest Oncology Group study

Robert P. Whitehead, Sheryl McCoy, John S. Macdonald, Saul E. Rivkin, Marcus A. Neubauer, Shaker R. Dakhil, Heinz-Josef Lenz, Michael S. Tanaka, James L. Abbruzzese

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 376 KB

english, 2006

4

A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC)

Tanios S. Bekaii-Saab, Amir Mortazavi, Lee G. Hicks, Mark Zalupski, Robert J. Pelley, Kenneth K. Chan, Eric H. Kraut

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

5

A phase I and pharmacokinetic study of irofulven and cisplatin administered in a 30-min infusion every two weeks to patients with advanced solid tumors

Werner Hilgers, Sandrine Faivre, Stéphanie Chieze, Jérôme Alexandre, François Lokiec, François Goldwasser, Eric Raymond, Carmen Kahatt, Abdelkrim Taamma, Garry Weems, John R. MacDonald, Jean-Louis Mis

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 266 KB

english, 2006

6

The Wnt-dependent signaling pathways as target in oncology drug discovery

Nico Janssens, Michel Janicot, Tim Perera

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 785 KB

english, 2006

7

Phase I trial of thalidomide and Interleukin-2 in patients with metastatic renal cell carcinoma

Thomas Olencki, Sareena Malhi, Tarek Mekhail, Robert Dreicer, Paul Elson, Laura Wood, Ronald M. Bukowski

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

8

Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells:in vitroand in cancer patients

Jing Li, Julie Brahmer, Wells Messersmith, Manuel Hidalgo, Sharyn D. Baker

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 397 KB

english, 2006

9

Population pharmacokinetics and bioavailability of motexafin gadolinium (Xcytrin®) in CD1 mice following intravenous and intraperitoneal injection

Boswell GW, DR Miles, PA Thiemann, M Mesfin

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 746 KB

english, 2006

10

A phase I clinical and pharmacokinetic study of CS-682 administered orally in advanced malignant solid tumors

Thierry Delaunoit, Patrick A. Burch, Joel M. Reid, John K. Camoriano, Tomowo Kobayash, Theodore A. Braich, Judith S. Kaur, Joseph Rubin, Charles Erlichman

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 530 KB

english, 2006

11

SarCNU in recurrent or metastatic colorectal cancer: A phase II study of the National Cancer Institute of Canada Clinical Trials Group

R. P. Wong, T. Baetz, M. J. Krahn, J. Biagi, N. Wainman, E. Eisenhauer

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 178 KB

english, 2006

12

Phase II study of rubitecan, an oral camptothecin in patients with advanced colorectal cancer who have failed previous 5-fluorouracil based chemotherapy

Hitendra Patel, Ronald Stoller, Miklos Auber, Douglas Potter, Chao Cai, William Zamboni, Gauri Kiefer, Khalid Matin, Amy Schmotzer, Ramesh K. Ramanathan

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 198 KB

english, 2006

13

A multi-center phase II study of sequential paclitaxel and bryostatin-1 (NSC 339555) in patients with untreated, advanced gastric or gastroesophageal junction adenocarcinoma

Jaffer A. Ajani, Yixing Jiang, Josephine Faust, Baochong B. Chang, Linus Ho, James C. Yao, Steven Rousey, Shaker Dakhil, Richard C. Cherny, Catherine Craig, Archie Bleyer

Journal:

Investigational New Drugs

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006