Volume 25; Issue 5

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Investigational New Drugs
Volume 25; Issue 5

Investigational New Drugs

Volume 25; Issue 5

1

Docetaxel–ifosfamide combination in patients withHER2-non-overexpressing advanced breast cancer failing prior anthracyclines

Christos Kosmas, Nicolas Tsavaris, Nikolaos Malamos, George Tsakonas, Argyris Gassiamis, Aristidis Polyzos, Nicolas Mylonakis, Athanasios Karabelis

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 164 KB

english, 2007

2

Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)

Jennifer J. Knox, Sebastien J. Hotte, Christian Kollmannsberger, Eric Winquist, Bryn Fisher, Elizabeth A. Eisenhauer

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 131 KB

english, 2007

3

The efficacy of hybrid chemotherapy with intravenous oxaliplatin and folinic acid and intra-hepatic infusion of 5-fluorouracil in patients with colorectal liver metastases: a phase II study

Carlo Carnaghi, Armando Santoro, Lorenza Rimassa, Roberto Doci, Riccardo Rosati, Vittorio Pedicini, Giuseppe Gullo, Monica Zuradelli, Giovanni Abbadessa, Emanuela Morenghi, Ilaria Marcon, Isabella Gar

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 157 KB

english, 2007

4

Phase I dose escalation and pharmacokinetic study of AZD2171, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinase, in patients with hormone refractory prostate cancer (HRPC)

Charles J. Ryan, Walter M. Stadler, Bruce Roth, Douglass Hutcheon, Shauna Conry, Thomas Puchalski, Charles Morris, Eric J. Small

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 154 KB

english, 2007

5

Silencing of endo-exonuclease expression sensitizes mouse B16F10 melanoma cells to DNA damaging agents

Sibgat A. Choudhury, Paul Kauler, Slobodan Devic, Terry Y-K Chow

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

6

Modulation of tumor radiation response with G3139, a bcl-2 antisense oligonucleotide

Nicole Wiedenmann, Masashi Koto, Uma Raju, Luka Milas, Kathryn A. Mason

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

7

Phase II Trial of ixabepilone in patients with cisplatin-refractory germ cell tumors

Darren R. Feldman, G. Varuni Kondagunta, Michelle S. Ginsberg, Nicole Ishill, Sujata Patil, John Cestaro, Eugenie Obbens, Joel Sheinfeld, George J. Bosl, Robert J. Motzer

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 87 KB

english, 2007

8

In vitro chemosensitivity of freshly explanted tumor cells to pemetrexed is correlated with target gene expression

Axel-Rainer Hanauske, Ulrike Eismann, Olaf Oberschmidt, Heike Pospisil, Steve Hoffmann, Hartmut Hanauske-Abel, Doreen Ma, Victor Chen, Paolo Paoletti, Clet Niyikiza

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 157 KB

english, 2007

9

Dimethylamino-functionalised andN-heteroaryl-substituted titanocene anticancer drugs: synthesis and cytotoxicity studies

Thomas Hickey, James Claffey, Eoin Fitzpatrick, Megan Hogan, Clara Pampillón, Matthias Tacke

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

10

Different cell cycle modulation following treatment of human ovarian carcinoma cells with a new platinum(IV) complex vs cisplatin

Viktor Horváth, Karel Souček, Lenka Švihálková-Šindlerová, Jan Vondráček, Olga Blanářová, Jiřina Hofmanová, Petr Sova, Alois Kozubík

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

11

Amrubicin for non-small-cell lung cancer and small-cell lung cancer

Takayasu Kurata, Isamu Okamoto, Kenji Tamura, Masahiro Fukuoka

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

12

Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines

Michela Biancolella, Alessandra Valentini, Daniela Minella, Lucia Vecchione, Franca D’Amico, Giovanni Chillemi, Paolo Gravina, Susana Bueno, Gianluca Prosperini, Alessandro Desideri, Giorgio Federici,

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

13

A phase I and pharmacokinetic study of irofulven and capecitabine administered every 2

Jérôme Alexandre, Carmen Kahatt, Frédérique Bertheault-Cvitkovic, Sandrine Faivre, Stephen Shibata, Werner Hilgers, François Goldwasser, François Lokiec, Eric Raymond, Garry Weems, Ajit Shah, John R.

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 188 KB

english, 2007