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Volume 28; Issue 6
Main
Investigational New Drugs
Volume 28; Issue 6
Investigational New Drugs
Volume 28; Issue 6
1
Phase I study of non-pegylated liposomal doxorubicin in combination with ifosfamide in adult patients with metastatic soft tissue sarcomas
Elisa Stroppa
,
Alexia Bertuzzi
,
Gabriele Di Comite
,
Chiara Mussi
,
Romano Fabio Lutman
,
Alfredo Barbato
,
Armando Santoro
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 106 KB
Your tags:
english, 2010
2
New SRC/ABL inhibitors for chronic myeloid leukemia therapy show selectivity for T315I ABL mutant CD34+cells
Maria Alessandra Santucci
,
Manuela Mancini
,
Valentina Corradi
,
Ilaria lacobucci
,
Giovanni Martinelli
,
Maurizio Botta
,
Silvia Schenone
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 145 KB
Your tags:
english, 2010
3
Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with Everolimus
Christophe Massard
,
Karim Fizazi
,
Marine Gross-Goupil
,
Bernard Escudier
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 176 KB
Your tags:
english, 2010
4
The epothilone B analogue ixabepilone in patients with advanced hepatobiliary cancers: a trial of the University of Chicago Phase II Consortium
Halla S. Nimeiri
,
Deepti A. Singh
,
Kristen Kasza
,
David A. Taber
,
Rafat H. Ansari
,
Everett E. Vokes
,
Hedy L. Kindler
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 113 KB
Your tags:
english, 2010
5
MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules
Zhixiang Zhang
,
Tao Meng
,
Jingxue He
,
Ming Li
,
Lin-Jiang Tong
,
Bing Xiong
,
Liping Lin
,
Jingkang Shen
,
Ze-Hong Miao
,
Jian Ding
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 915 KB
Your tags:
english, 2010
6
NBBS isolated fromPygeum africanumbark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth
Maria Papaioannou
,
Sonja Schleich
,
Daniela Roell
,
Undine Schubert
,
Tamzin Tanner
,
Frank Claessens
,
Rudolf Matusch
,
Aria Baniahmad
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 344 KB
Your tags:
english, 2010
7
Phase II study of gemcitabine and carboplatin in metastatic breast cancers with prior exposure to anthracyclines and taxanes
Daniel Chan
,
Wee-Lee Yeo
,
Maricel Tiemsim Cordero
,
Chiung-Ing Wong
,
Benjamin Chuah
,
Ross Soo
,
Sing-Huang Tan
,
Siew-Eng Lim
,
Boon-Cher Goh
,
Soo-Chin Lee
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 133 KB
Your tags:
english, 2010
8
Phase I/II study of sunitinib malate in Japanese patients with gastrointestinal stromal tumor after failure of prior treatment with imatinib mesylate
Kuniaki Shirao
,
Toshirou Nishida
,
Toshihiko Doi
,
Yoshito Komatsu
,
Kei Muro
,
Yinhua Li
,
Eiji Ueda
,
Atsushi Ohtsu
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 188 KB
Your tags:
english, 2010
9
Scaling the time-course of myelosuppression from rats to patients with a semi-physiological model
Lena E. Friberg
,
Marie Sandström
,
Mats O. Karlsson
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 423 KB
Your tags:
english, 2010
10
Synthesis, characterization andin vitroanti-tumor activities of novel 9-ethyl-9H-purine derivatives
Raghu Ningegowda
,
Amit Grover
,
Basappa
,
S. Ranjith
,
Kanchugarakoppal S. Rangappa
,
B. S. Priya
,
S. Nanjunda Swamy
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 273 KB
Your tags:
english, 2010
11
Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells
Pay-Chin Leow
,
Quan Tian
,
Zhan-Yuin Ong
,
Zheng Yang
,
Pui-Lai Rachel Ee
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 580 KB
Your tags:
english, 2010
12
Painful cervical esophageal erosion in a patient with advanced colorectal cancer treated with bevacizumab
Carlos Eduardo Paiva
,
Yara Cristina de Paiva Maia
,
Bianca Sakamoto Ribeiro Paiva
,
Mauro Masson Lerco
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 85 KB
Your tags:
english, 2010
13
DH9, a novel PPARγ agonist suppresses the proliferation of ADPKD epithelial cells: An association with an inhibition of β-catenin signaling
Moyan Liu
,
Lili Fu
,
Chunyan Liu
,
Xishan Xiong
,
Xiang Gao
,
Min Xiao
,
Houan Cai
,
Huimin Hu
,
Xueqi Wang
,
Changlin Mei
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 553 KB
Your tags:
english, 2010
14
Dysphonia induced by vascular endothelium growth factor/vascular endothelium growth factor receptor inhibitors
Dana M. Hartl
,
Charles Ferté
,
Yohann Loriot
,
Carlos Gomez Roca
,
Rastislav Bahleda
,
Cristian Moldovan
,
Olivier Mir
,
Jean-Charles Soria
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 119 KB
Your tags:
english, 2010
15
Justification of the starting dose as the main determinant of accrual time in dose-seeking oncology phase 1 trials
Nicolas Penel
,
Pierre Leblond
,
Amélie Lansiaux
,
Stéphanie Clisant
,
Eric Dansin
,
Antoine Adenis
,
Jacques Bonneterre
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 127 KB
Your tags:
english, 2010
16
Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells withK-Rasmutations
In Hae Park
,
Jin Young Kim
,
Jae In Jung
,
Ji-Youn Han
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 541 KB
Your tags:
english, 2010
17
Phase I clinical and pharmacokinetic study of sorafenib in combination with carboplatin and paclitaxel in patients with advanced non–small cell lung cancer
Isamu Okamoto
,
Masaki Miyazaki
,
Ryotaro Morinaga
,
Hiroyasu Kaneda
,
Shinya Ueda
,
Yoshikazu Hasegawa
,
Taroh Satoh
,
Akira Kawada
,
Masahiro Fukuoka
,
Koichi Fukino
,
Takahiko Tanigawa
,
Kazuhiko Nakagawa
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 312 KB
Your tags:
english, 2010
18
Antimetastatic activity of MONCPT in preclinical melanoma mice model
Xiao-Chun Yang
,
Chong-Xing Tu
,
Pei-Hua Luo
,
Hong Zhu
,
Di-Feng Zhu
,
Hong-Hai Wu
,
Xing-Lu Zhou
,
Wei Lu
,
Qiao-Jun He
,
Bo Yang
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 862 KB
Your tags:
english, 2010
19
Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification
Subhasree Roy Choudhury
,
Surajit Karmakar
,
Naren L. Banik
,
Swapan K. Ray
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 816 KB
Your tags:
english, 2010
20
TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis
Alexander Schultze
,
Sebastian Decker
,
Jasmin Otten
,
Andrea Kristina Horst
,
Gabi Vohwinkel
,
Gunter Schuch
,
Carsten Bokemeyer
,
Sonja Loges
,
Walter Fiedler
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 306 KB
Your tags:
english, 2010
21
Complete remission of ovarian cancer induced intractable malignant ascites with intraperitoneal bevacizumab. Immunological observations and a literature review
Filippo Bellati
,
Chiara Napoletano
,
Ilary Ruscito
,
Maria Pastore
,
Milena Pernice
,
Morena Antonilli
,
Marianna Nuti
,
Pierluigi Benedetti Panici
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 233 KB
Your tags:
english, 2010
22
Erratum to: Antimetastatic activity of MONCPT in preclinical melanoma mice model
Xiao-Chun Yang
,
Chong-Xing Tu
,
Pei-Hua Luo
,
Hong Zhu
,
Di-Feng Zhu
,
Hong-Hai Wu
,
Xing-Lu Zhou
,
Wei Lu
,
Qiao-Jun He
,
Bo Yang
Journal:
Investigational New Drugs
Year:
2010
Language:
english
File:
PDF, 50 KB
Your tags:
english, 2010
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