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Volume 35; Issue 2
Main
Investigational New Drugs
Volume 35; Issue 2
Investigational New Drugs
Volume 35; Issue 2
1
Alofanib, an allosteric FGFR2 inhibitor, has potent effects on ovarian cancer growth in preclinical studies
Tyulyandina, Alexandra
,
Harrison, Daniel
,
Yin, Wei
,
Stepanova, Evgenia
,
Kochenkov, Dmitry
,
Solomko, Eliso
,
Peretolchina, Nina
,
Daeyaert, Frits
,
Joos, Jean-Baptiste
,
Van Aken, Koen
,
Byakhov, Mikhail
,
G
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 3.82 MB
Your tags:
english, 2017
2
Safety of raltegravir-based antiretroviral therapy in HIV-infected patients receiving multi-kinase inhibitors
Loulergue, Pierre
,
Merad, Mansouria
,
Coriat, Romain
,
Ducreux, Michel
,
Planchard, David
,
Boige, Valérie
,
Le Cesne, Axel
,
Gregory, Thomas M.
,
Poinsignon, Vianney
,
Paci, Angelo
,
Mir, Olivier
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 239 KB
Your tags:
english, 2017
3
Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors
Paz-Ares, Luis
,
Forster, Martin
,
Boni, Valentina
,
Szyldergemajn, Sergio
,
Corral, Jesús
,
Turnbull, Samantha
,
Cubillo, Antonio
,
Teruel, Carlos Fernandez
,
Calderero, Iker López
,
Siguero, Mariano
,
Bohan,
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 329 KB
Your tags:
english, 2017
4
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors
Beg, Muhammad S.
,
Brenner, Andrew J.
,
Sachdev, Jasgit
,
Borad, Mitesh
,
Kang, Yoon-Koo
,
Stoudemire, Jay
,
Smith, Susan
,
Bader, Andreas G.
,
Kim, Sinil
,
Hong, David S.
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 532 KB
Your tags:
english, 2017
5
Phase I study of Nivolumab, an anti-PD-1 antibody, in patients with malignant solid tumors
Yamamoto, Noboru
,
Nokihara, Hiroshi
,
Yamada, Yasuhide
,
Shibata, Takashi
,
Tamura, Yosuke
,
Seki, Yoshitaka
,
Honda, Kazunori
,
Tanabe, Yuko
,
Wakui, Hiroshi
,
Tamura, Tomohide
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 500 KB
Your tags:
english, 2017
6
Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species
Lundberg, Alycen P.
,
Francis, Joshua M.
,
Pajak, Malgorzata
,
Parkinson, Elizabeth I.
,
Wycislo, Kathryn L.
,
Rosol, Thomas J.
,
Brown, Megan E.
,
London, Cheryl A.
,
Dirikolu, Levent
,
Hergenrother, Paul J.
,
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 1.30 MB
Your tags:
english, 2017
7
Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth
Shelake, Sagar
,
Sankpal, Umesh T.
,
Paul Bowman, W.
,
Wise, Matthew
,
Ray, Anish
,
Basha, Riyaz
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 1005 KB
Your tags:
english, 2017
8
Zebrafish phenotypic screen identifies novel Notch antagonists
Velaithan, Vithya
,
Okuda, Kazuhide Shaun
,
Ng, Mei Fong
,
Samat, Norazwana
,
Leong, Sze Wei
,
Faudzi, Siti Munirah Mohd
,
Abas, Faridah
,
Shaari, Khozirah
,
Cheong, Sok Ching
,
Tan, Pei Jean
,
Patel, Vyomesh
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 5.44 MB
Your tags:
english, 2017
9
Sunitinib-paracetamol sex-divergent pharmacokinetics and tissue distribution drug-drug interaction in mice
Liew, Ming Hui
,
Ng, Salby
,
Chew, Chii Chii
,
Koo, Teng Wai
,
Chee, Yun Lee
,
Chee, Evelyn Li-Ching
,
Modamio, Pilar
,
Fernández, Cecilia
,
Mariño, Eduardo L.
,
Segarra, Ignacio
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 1.16 MB
Your tags:
english, 2017
10
Phase I/II study of docetaxel combined with resminostat, an oral hydroxamic acid HDAC inhibitor, for advanced non-small cell lung cancer in patients previously treated with platinum-based chemotherapy
Tambo, Yuichi
,
Hosomi, Yukio
,
Sakai, Hiroshi
,
Nogami, Naoyuki
,
Atagi, Shinji
,
Sasaki, Yasutsuna
,
Kato, Terufumi
,
Takahashi, Toshiaki
,
Seto, Takashi
,
Maemondo, Makoto
,
Nokihara, Hiroshi
,
Koyama, Ryo
,
N
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 707 KB
Your tags:
english, 2017
11
A phase II study of carboplatin plus weekly paclitaxel with bevacizumab for elderly patients with non-squamous non-small-cell lung cancer (NEJ016)
Miura, Satoru
,
Maemondo, Makoto
,
Iwashima, Akira
,
Harada, Toshiyuki
,
Sugawara, Shunichi
,
Kobayashi, Kunihiko
,
Inoue, Akira
,
Nakagawa, Taku
,
Takiguchi, Yuichi
,
Watanabe, Hiroshi
,
Ishida, Takashi
,
Terad
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 647 KB
Your tags:
english, 2017
12
Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C
Almhanna, Khaldoun
,
Miron, Maria Luisa Limon
,
Wright, David
,
Gracian, Antonio Cubillo
,
Hubner, Richard A.
,
Van Laethem, Jean-Luc
,
López, Carolina Muriel
,
Alsina, Maria
,
Muñoz, Frederico Longo
,
Bendell
Journal:
Investigational New Drugs
Year:
2017
File:
PDF, 5 KB
Your tags:
2017
13
A phase 1 study of the pharmacokinetics of nucleoside analog trifluridine and thymidine phosphorylase inhibitor tipiracil (components of TAS-102) vs trifluridine alone
Cleary, James M.
,
Rosen, Lee S.
,
Yoshida, Kenichiro
,
Rasco, Drew
,
Shapiro, Geoffrey I.
,
Sun, Weijing
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 466 KB
Your tags:
english, 2017
14
Erratum to: Zebrafish phenotypic screen identifies novel Notch antagonists
Vithya Velaithan,Kazuhide Shaun Okuda,Mei Fong Ng…
Journal:
Investigational New Drugs
Year:
2017
Language:
english
File:
PDF, 185 KB
Your tags:
english, 2017
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