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Volume 289; Issue 27

Journal of Biological Chemistry

Volume 289; Issue 27

1

Rescue of Enzymatic Function for Disease-associated RPE65 Proteins Containing Various Missense Mutations in Non-active Sites

Li, S., Izumi, T., Hu, J., Jin, H. H., Siddiqui, A.-A. A., Jacobson, S. G., Bok, D., Jin, M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.60 MB

english, 2014

2

Structural Determinants of Phosphatidylinositol 4,5-Bisphosphate (PIP2) Regulation of BK Channel Activity through the RCK1 Ca2+ Coordination Site

Tang, Q.-Y., Zhang, Z., Meng, X.-Y., Cui, M., Logothetis, D. E.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.89 MB

english, 2014

3

Structural Basis for Dimerization and Catalysis of a Novel Esterase from the GTSAG Motif Subfamily of the Bacterial Hormone-sensitive Lipase Family

Li, P.-Y., Ji, P., Li, C.-Y., Zhang, Y., Wang, G.-L., Zhang, X.-Y., Xie, B.-B., Qin, Q.-L., Chen, X.-L., Zhou, B.-C., Zhang, Y.-Z.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

4

Caspase-activated DNase Is Necessary and Sufficient for Oligonucleosomal DNA Breakdown, but Not for Chromatin Disassembly during Caspase-dependent Apoptosis of LN-18 Glioblastoma Cells

Sanchez-Osuna, M., Garcia-Belinchon, M., Iglesias-Guimarais, V., Gil-Guinon, E., Casanelles, E., Yuste, V. J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 6.09 MB

english, 2014

5

Palmitoylation-dependent Membrane Localization of the Rice Resistance Protein Pit Is Critical for the Activation of the Small GTPase OsRac1

Kawano, Y., Fujiwara, T., Yao, A., Housen, Y., Hayashi, K., Shimamoto, K.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

6

Phosphorylation of Two Sites Is Key to the Function of the Neuronal Potassium Chloride Cotransporter KCC2 : A Novel Regulatory Locus of Phosphorylation in the C Terminus of the Potassium Chloride Cotransporter KCC2 That Interferes with N-Ethylmaleimide or Staurosporine-mediated Activation

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 96 KB

english, 2014

7

Structural and Electronic Snapshots during the Transition from a Cu(II) to Cu(I) Metal Center of a Lytic Polysaccharide Monooxygenase by X-ray Photoreduction

Gudmundsson, M., Kim, S., Wu, M., Ishida, T., Momeni, M. H., Vaaje-Kolstad, G., Lundberg, D., Royant, A., Stahlberg, J., Eijsink, V. G. H., Beckham, G. T., Sandgren, M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.59 MB

english, 2014

8

YfgM Is an Ancillary Subunit of the SecYEG Translocon in Escherichia coli

Gotzke, H., Palombo, I., Muheim, C., Perrody, E., Genevaux, P., Kudva, R., Muller, M., Daley, D. O.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.83 MB

english, 2014

9

FABP3 Protein Promotes -Synuclein Oligomerization Associated with 1-Methyl-1,2,3,6-tetrahydropiridine-induced Neurotoxicity

Shioda, N., Yabuki, Y., Kobayashi, Y., Onozato, M., Owada, Y., Fukunaga, K.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.44 MB

english, 2014

10

Requirement for Pectin Methyl Esterase and Preference for Fragmented over Native Pectins for Wall-associated Kinase-activated, EDS1/PAD4-dependent Stress Response in Arabidopsis

Kohorn, B. D., Kohorn, S. L., Saba, N. J., Martinez, V. M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

11

Identification of the Flagellin Glycosylation System in Burkholderia cenocepacia and the Contribution of Glycosylated Flagellin to Evasion of Human Innate Immune Responses

Hanuszkiewicz, A., Pittock, P., Humphries, F., Moll, H., Rosales, A. R., Molinaro, A., Moynagh, P. N., Lajoie, G. A., Valvano, M. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.03 MB

english, 2014

12

Cross-talk Phosphorylations by Protein Kinase C and Pho85p-Pho80p Protein Kinase Regulate Pah1p Phosphatidate Phosphatase Abundance in Saccharomyces cerevisiae

Su, W.-M., Han, G.-S., Carman, G. M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

13

Trafficking of -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor (AMPA) Receptor Subunit GluA2 from the Endoplasmic Reticulum Is Stimulated by a Complex Containing Ca2+/Calmodulin-activated Kinase II (CaMKII) and PICK1 Protein and by Release of Ca2+ from Internal Stores

Lu, W., Khatri, L., Ziff, E. B.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.14 MB

english, 2014

14

Constitutively Oxidized CXXC Motifs within the CD3 Heterodimeric Ectodomains of the T Cell Receptor Complex Enforce the Conformation of Juxtaposed Segments

Brazin, K. N., Mallis, R. J., Li, C., Keskin, D. B., Arthanari, H., Gao, Y., Wu, S.-L., Karger, B. L., Wagner, G., Reinherz, E. L.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.29 MB

english, 2014

15

The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease

Mohanan, V., Grimes, C. L.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

16

The Association of Hepatitis C Virus Glycoproteins with Apolipoproteins E and B Early in Assembly Is Conserved in Lipoviral Particles

Boyer, A., Dumans, A., Beaumont, E., Etienne, L., Roingeard, P., Meunier, J.-C.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

17

A Domain in the Transcription Activator Gln3 Specifically Required for Rapamycin Responsiveness

Rai, R., Tate, J. J., Shanmuganatham, K., Howe, M. M., Cooper, T. G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 9.42 MB

english, 2014

18

Regulation of Nuclear Translocation of the Myb1 Transcription Factor by TvCyclophilin 1 in the Protozoan Parasite Trichomonas vaginalis

Hsu, H.-M., Chu, C.-H., Wang, Y.-T., Lee, Y., Wei, S.-Y., Liu, H.-W., Ong, S.-J., Chen, C., Tai, J.-H.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.40 MB

english, 2014

19

A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demonstrating Unique Molecular Properties

Schanzer, J. M., Wartha, K., Croasdale, R., Moser, S., Kunkele, K.-P., Ries, C., Scheuer, W., Duerr, H., Pompiati, S., Pollman, J., Stracke, J., Lau, W., Ries, S., Brinkmann, U., Klein, C., Umana, P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.68 MB

english, 2014

20

Epidermal growth factor (EGF)-enhanced vascular cell adhesion molecule-1 (VCAM-1) expression promotes macrophage and glioblastoma cell interaction and tumor cell invasion.

Zheng, Y., Yang, W., Aldape, K., He, J., Lu, Z.

Journal:

Journal of Biological Chemistry

Year:

2014

File:

PDF, 36 KB

2014

21

UBE2E Ubiquitin-conjugating Enzymes and Ubiquitin Isopeptidase Y Regulate TDP-43 Protein Ubiquitination

Hans, F., Fiesel, F. C., Strong, J. C., Jackel, S., Rasse, T. M., Geisler, S., Springer, W., Schulz, J. B., Voigt, A., Kahle, P. J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.93 MB

english, 2014

22

The Epigenetic Drug 5-Azacytidine Interferes with Cholesterol and Lipid Metabolism

Poirier, S., Samami, S., Mamarbachi, M., Demers, A., Chang, T. Y., Vance, D. E., Hatch, G. M., Mayer, G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.14 MB

english, 2014

23

Neutrophils Generate Microparticles during Exposure to Inert Gases Due to Cytoskeletal Oxidative Stress

Thom, S. R., Bhopale, V. M., Yang, M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

24

Ca2+ Influx via the Na+/Ca2+ Exchanger Is Enhanced in Malignant Hyperthermia Skeletal Muscle

Altamirano, F., Eltit, J. M., Robin, G., Linares, N., Ding, X., Pessah, I. N., Allen, P. D., Lopez, J. R.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.55 MB

english, 2014

25

Cytosolic Branched Chain Aminotransferase (BCATc) Regulates mTORC1 Signaling and Glycolytic Metabolism in CD4+ T Cells

Ananieva, E. A., Patel, C. H., Drake, C. H., Powell, J. D., Hutson, S. M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.88 MB

english, 2014

26

Oligomerization Inhibits Legionella pneumophila PlaB Phospholipase A Activity

Kuhle, K., Krausze, J., Curth, U., Rossle, M., Heuner, K., Lang, C., Flieger, A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

27

Study of the Protein Complex, Pore Diameter, and Pore-forming Activity of the Borrelia burgdorferi P13 Porin

Barcena-Uribarri, I., Thein, M., Barbot, M., Sans-Serramitjana, E., Bonde, M., Mentele, R., Lottspeich, F., Bergstrom, S., Benz, R.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

28

Proposed Carrier Lipid-binding Site of Undecaprenyl Pyrophosphate Phosphatase from Escherichia coli

Chang, H.-Y., Chou, C.-C., Hsu, M.-F., Wang, A. H. J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.01 MB

english, 2014

29

Targeting Spare CC Chemokine Receptor 5 (CCR5) as a Principle to Inhibit HIV-1 Entry

Jin, J., Colin, P., Staropoli, I., Lima-Fernandes, E., Ferret, C., Demir, A., Rogee, S., Hartley, O., Randriamampita, C., Scott, M. G. H., Marullo, S., Sauvonnet, N., Arenzana-Seisdedos, F., Lagane, B

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.86 MB

english, 2014

30

Cu(I)-mediated Allosteric Switching in a Copper-sensing Operon Repressor (CsoR)

Chang, F.-M. J., Coyne, H. J., Cubillas, C., Vinuesa, P., Fang, X., Ma, Z., Ma, D., Helmann, J. D., Garcia-de los Santos, A., Wang, Y.-X., Dann, C. E., Giedroc, D. P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 7.84 MB

english, 2014

31

Identification of Functionally Important Residues of the Silkmoth Pheromone Biosynthesis-activating Neuropeptide Receptor, an Insect Ortholog of the Vertebrate Neuromedin U Receptor

Kawai, T., Katayama, Y., Guo, L., Liu, D., Suzuki, T., Hayakawa, K., Lee, J. M., Nagamine, T., Hull, J. J., Matsumoto, S., Nagasawa, H., Tanokura, M., Nagata, K.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.58 MB

english, 2014

32

NdhP Is an Exclusive Subunit of Large Complex of NADPH Dehydrogenase Essential to Stabilize the Complex in Synechocystis sp. Strain PCC 6803

Zhang, J., Gao, F., Zhao, J., Ogawa, T., Wang, Q., Ma, W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.55 MB

english, 2014

33

Structural Insights into the Lipoprotein Outer Membrane Regulator of Penicillin-binding Protein 1B

King, D. T., Lameignere, E., Strynadka, N. C. J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.75 MB

english, 2014

34

SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development

Tu, C.-F., Tsao, K.-C., Lee, S.-J., Yang, R.-B.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.79 MB

english, 2014

35

Sialyl-lactotetra, a Novel Cell Surface Marker of Undifferentiated Human Pluripotent Stem Cells

Barone, A., Saljo, K., Benktander, J., Blomqvist, M., Mansson, J.-E., Johansson, B. R., Molne, J., Aspegren, A., Bjorquist, P., Breimer, M. E., Teneberg, S.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.02 MB

english, 2014

36

Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion

Zhang, H., von Gise, A., Liu, Q., Hu, T., Tian, X., He, L., Pu, W., Huang, X., He, L., Cai, C.-L., Camargo, F. D., Pu, W. T., Zhou, B.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.15 MB

english, 2014

37

Sequential Actions of the AAA-ATPase Valosin-containing Protein (VCP)/p97 and the Proteasome 19 S Regulatory Particle in Sterol-accelerated, Endoplasmic Reticulum (ER)-associated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Morris, L. L., Hartman, I. Z., Jun, D.-J., Seemann, J., DeBose-Boyd, R. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.64 MB

english, 2014

38

Casein Kinase 1 -dependent Wee1 Protein Degradation

Penas, C., Ramachandran, V., Simanski, S., Lee, C., Madoux, F., Rahaim, R. J., Chauhan, R., Barnaby, O., Schurer, S., Hodder, P., Steen, J., Roush, W. R., Ayad, N. G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.52 MB

english, 2014

39

The Dectin 1 Agonist Curdlan Regulates Osteoclastogenesis by Inhibiting Nuclear Factor of Activated T cells Cytoplasmic 1 (NFATc1) through Syk Kinase

Yamasaki, T., Ariyoshi, W., Okinaga, T., Adachi, Y., Hosokawa, R., Mochizuki, S., Sakurai, K., Nishihara, T.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.90 MB

english, 2014

40

The P2Y2 Nucleotide Receptor Mediates the Proliferation and Migration of Human Hepatocellular Carcinoma Cells Induced by ATP

Xie, R., Xu, J., Wen, G., Jin, H., Liu, X., Yang, Y., Ji, B., Jiang, Y., Song, P., Dong, H., Tuo, B.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.48 MB

english, 2014

41

A Novel Regulatory Locus of Phosphorylation in the C Terminus of the Potassium Chloride Cotransporter KCC2 That Interferes with N-Ethylmaleimide or Staurosporine-mediated Activation

Weber, M., Hartmann, A.-M., Beyer, T., Ripperger, A., Nothwang, H. G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.07 MB

english, 2014

42

Control of Insulin Secretion by Cytochrome c and Calcium Signaling in Islets with Impaired Metabolism

Rountree, A. M., Neal, A. S., Lisowski, M., Rizzo, N., Radtke, J., White, S., Luciani, D. S., Kim, F., Hampe, C. S., Sweet, I. R.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.20 MB

english, 2014

43

Promyelocytic Leukemia Zinc Finger-Retinoic Acid Receptor (PLZF-RAR ), an Oncogenic Transcriptional Repressor of Cyclin-dependent Kinase Inhibitor 1A (p21WAF/CDKN1A) and Tumor Protein p53 (TP53) Genes

Choi, W.-I., Yoon, J.-H., Kim, M.-Y., Koh, D.-I., Licht, J. D., Kim, K., Hur, M.-W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 8.71 MB

english, 2014

44

Role of Promyelocytic Leukemia Zinc Finger (PLZF) in Cell Proliferation and Cyclin-dependent Kinase Inhibitor 1A (p21WAF/CDKN1A) Gene Repression

Choi, W.-I., Kim, M.-Y., Jeon, B.-N., Koh, D.-I., Yun, C.-O., Li, Y., Lee, C.-E., Oh, J., Kim, K., Hur, M.-W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 10.10 MB

english, 2014

45

Proteolytic Activation of the Human Epithelial Sodium Channel by Trypsin IV and Trypsin I Involves Distinct Cleavage Sites

Haerteis, S., Krappitz, A., Krappitz, M., Murphy, J. E., Bertog, M., Krueger, B., Nacken, R., Chung, H., Hollenberg, M. D., Knecht, W., Bunnett, N. W., Korbmacher, C.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.43 MB

english, 2014

46

Novel Zinc-binding Site in the E2 Domain Regulates Amyloid Precursor-like Protein 1 (APLP1) Oligomerization

Mayer, M. C., Kaden, D., Schauenburg, L., Hancock, M. A., Voigt, P., Roeser, D., Barucker, C., Than, M. E., Schaefer, M., Multhaup, G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.70 MB

english, 2014

47

Separate Intramolecular Targets for Protein Kinase A Control N-Methyl-D-aspartate Receptor Gating and Ca2+ Permeability

Aman, T. K., Maki, B. A., Ruffino, T. J., Kasperek, E. M., Popescu, G. K.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.84 MB

english, 2014

48

Histone Modifications Are Associated with 9-Tetrahydrocannabinol-mediated Alterations in Antigen-specific T Cell Responses

Yang, X., Hegde, V. L., Rao, R., Zhang, J., Nagarkatti, P. S., Nagarkatti, M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.15 MB

english, 2014

49

Increased C-telopeptide Cross-linking of Tendon Type I Collagen in Fibromodulin-deficient Mice

Kalamajski, S., Liu, C., Tillgren, V., Rubin, K., Oldberg, A., Rai, J., Weis, M., Eyre, D. R.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.90 MB

english, 2014

50

Structural-Functional Analysis of the Third Transmembrane Domain of the Corticotropin-releasing Factor Type 1 Receptor: ROLE IN ACTIVATION AND ALLOSTERIC ANTAGONISM

Spyridaki, K., Matsoukas, M.-T., Cordomi, A., Gkountelias, K., Papadokostaki, M., Mavromoustakos, T., Logothetis, D. E., Margioris, A. N., Pardo, L., Liapakis, G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.22 MB

english, 2014

51

Identification of Mixed Lineage Leukemia 1(MLL1) Protein as a Coactivator of Heat Shock Factor 1(HSF1) Protein in Response to Heat Shock Protein 90 (HSP90) Inhibition

Chen, Y., Chen, J., Yu, J., Yang, G., Temple, E., Harbinski, F., Gao, H., Wilson, C., Pagliarini, R., Zhou, W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.44 MB

english, 2014

52

Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore

Skals, M., Bjaelde, R. G., Reinholdt, J., Poulsen, K., Vad, B. S., Otzen, D. E., Leipziger, J., Praetorius, H. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014