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Volume 289; Issue 33

Journal of Biological Chemistry

Volume 289; Issue 33

1

Role of Protein Phosphatase 1 in Dephosphorylation of Ebola Virus VP30 Protein and Its Targeting for the Inhibition of Viral Transcription

Ilinykh, P. A., Tigabu, B., Ivanov, A., Ammosova, T., Obukhov, Y., Garron, T., Kumari, N., Kovalskyy, D., Platonov, M. O., Naumchik, V. S., Freiberg, A. N., Nekhai, S., Bukreyev, A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.54 MB

english, 2014

2

MDM2 Regulates Hypoxic Hypoxia-inducible Factor 1 Stability in an E3 Ligase, Proteasome, and PTEN-Phosphatidylinositol 3-Kinase-AKT-dependent Manner

Joshi, S., Singh, A. R., Durden, D. L.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.13 MB

english, 2014

3

SLC17A9 Protein Functions as a Lysosomal ATP Transporter and Regulates Cell Viability

Cao, Q., Zhao, K., Zhong, X. Z., Zou, Y., Yu, H., Huang, P., Xu, T.-L., Dong, X.-P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.18 MB

english, 2014

4

Phospholipase D and the Maintenance of Phosphatidic Acid Levels for Regulation of Mammalian Target of Rapamycin (mTOR)

Foster, D. A., Salloum, D., Menon, D., Frias, M. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

5

Replication Intermediates of the Linear Mitochondrial DNA of Candida parapsilosis Suggest a Common Recombination Based Mechanism for Yeast Mitochondria

Gerhold, J. M., Sedman, T., Visacka, K., Slezakova, J., Tomaska, L., Nosek, J., Sedman, J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.24 MB

english, 2014

6

Crystal Structure of the Chlamydomonas Starch Debranching Enzyme Isoamylase ISA1 Reveals Insights into the Mechanism of Branch Trimming and Complex Assembly

Sim, L., Beeren, S. R., Findinier, J., Dauvillee, D., Ball, S. G., Henriksen, A., Palcic, M. M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.66 MB

english, 2014

7

5'-AMP-activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experimental Human Breast Cancer Tumors

Laderoute, K. R., Calaoagan, J. M., Chao, W.-r., Dinh, D., Denko, N., Duellman, S., Kalra, J., Liu, X., Papandreou, I., Sambucetti, L., Boros, L. G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.56 MB

english, 2014

8

A Novel Interaction between the SH2 Domain of Signaling Adaptor Protein Nck-1 and the Upstream Regulator of the Rho Family GTPase Rac1 Engulfment and Cell Motility 1 (ELMO1) Promotes Rac1 Activation and Cell Motility

Zhang, G., Chen, X., Qiu, F., Zhu, F., Lei, W., Nie, J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.03 MB

english, 2014

9

Targeting the Ion Channel Kv1.3 with Scorpion Venom Peptides Engineered for Potency, Selectivity, and Half-life

Edwards, W., Fung-Leung, W.-P., Huang, C., Chi, E., Wu, N., Liu, Y., Maher, M. P., Bonesteel, R., Connor, J., Fellows, R., Garcia, E., Lee, J., Lu, L., Ngo, K., Scott, B., Zhou, H., Swanson, R. V., Wi

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

10

Unique Properties of Human -Defensin 6 (hBD6) and Glycosaminoglycan Complex: SANDWICH-LIKE DIMERIZATION AND COMPETITION WITH THE CHEMOKINE RECEPTOR 2 (CCR2) BINDING SITE

De Paula, V. S., Pomin, V. H., Valente, A. P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.93 MB

english, 2014

11

Unstable Reaction Intermediates and Hysteresis during the Catalytic Cycle of 5-Aminolevulinate Synthase: IMPLICATIONS FROM USING PSEUDO AND ALTERNATE SUBSTRATES AND A PROMISCUOUS ENZYME VARIANT

Stojanovski, B. M., Hunter, G. A., Jahn, M., Jahn, D., Ferreira, G. C.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

12

Novel Kv7.1-Phosphatidylinositol 4,5-Bisphosphate Interaction Sites Uncovered by Charge Neutralization Scanning

Eckey, K., Wrobel, E., Strutz-Seebohm, N., Pott, L., Schmitt, N., Seebohm, G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.40 MB

english, 2014

13

Cellular and Physiological Roles for Phospholipase D1 in Cancer

Zhang, Y., Frohman, M. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 994 KB

english, 2014

14

Functional Regulation of Phospholipase D Expression in Cancer and Inflammation

Kang, D. W., Choi, K.-Y., Min, D. S.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

15

Metformin Suppresses Lipopolysaccharide (LPS)-induced Inflammatory Response in Murine Macrophages via Activating Transcription Factor-3 (ATF-3) Induction

Kim, J., Kwak, H. J., Cha, J.-Y., Jeong, Y.-S., Rhee, S. D., Kim, K. R., Cheon, H. G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.63 MB

english, 2014

16

Mechanistic Study of Uba5 Enzyme and the Ufm1 Conjugation Pathway

Gavin, J. M., Hoar, K., Xu, Q., Ma, J., Lin, Y., Chen, J., Chen, W., Bruzzese, F. J., Harrison, S., Mallender, W. D., Bump, N. J., Sintchak, M. D., Bence, N. F., Li, P., Dick, L. R., Gould, A. E., Che

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

17

Alternative Conformations of the Tau Repeat Domain in Complex with an Engineered Binding Protein

Gruning, C. S. R., Mirecka, E. A., Klein, A. N., Mandelkow, E., Willbold, D., Marino, S. F., Stoldt, M., Hoyer, W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.06 MB

english, 2014

18

Suppression of the DHX9 Helicase Induces Premature Senescence in Human Diploid Fibroblasts in a p53-dependent Manner

Lee, T., Di Paola, D., Malina, A., Mills, J. R., Kreps, A., Grosse, F., Tang, H., Zannis-Hadjopoulos, M., Larsson, O., Pelletier, J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

19

Histone Cross-talk Connects Protein Phosphatase 1 (PP1 ) and Histone Deacetylase (HDAC) Pathways to Regulate the Functional Transition of Bromodomain-containing 4 (BRD4) for Inducible Gene Expression

Hu, X., Lu, X., Liu, R., Ai, N., Cao, Z., Li, Y., Liu, J., Yu, B., Liu, K., Wang, H., Zhou, C., Wang, Y., Han, A., Ding, F., Chen, R.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.54 MB

english, 2014

20

Structure and Function of the Bacterial Heterodimeric ABC Transporter CydDC: STIMULATION OF ATPASE ACTIVITY BY THIOL AND HEME COMPOUNDS

Yamashita, M., Shepherd, M., Booth, W. I., Xie, H., Postis, V., Nyathi, Y., Tzokov, S. B., Poole, R. K., Baldwin, S. A., Bullough, P. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.88 MB

english, 2014

21

Platelet-derived Growth Factor Primes Cancer-associated Fibroblasts for Apoptosis

Rizvi, S., Mertens, J. C., Bronk, S. F., Hirsova, P., Dai, H., Roberts, L. R., Kaufmann, S. H., Gores, G. J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

22

Ki67 Antigen Contributes to the Timely Accumulation of Protein Phosphatase 1 on Anaphase Chromosomes

Takagi, M., Nishiyama, Y., Taguchi, A., Imamoto, N.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.91 MB

english, 2014

23

The C-terminal Tails of the Bacterial Chaperonin GroEL Stimulate Protein Folding by Directly Altering the Conformation of a Substrate Protein

Weaver, J., Rye, H. S.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.00 MB

english, 2014

24

Dissection of the Adenoviral VA RNAI Central Domain Structure Reveals Minimum Requirements for RNA-mediated Inhibition of PKR

Wilson, J. L., Vachon, V. K., Sunita, S., Schwartz, S. L., Conn, G. L.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.55 MB

english, 2014

25

NADPH Oxidase 4 Induces Cardiac Arrhythmic Phenotype in Zebrafish

Zhang, Y., Shimizu, H., Siu, K. L., Mahajan, A., Chen, J.-N., Cai, H.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

26

The -Subunit Regulates Stability of the Metal Ion at the Ligand-associated Metal Ion-binding Site in 3 Integrins

Rui, X., Mehrbod, M., Van Agthoven, J. F., Anand, S., Xiong, J.-P., Mofrad, M. R. K., Arnaout, M. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.06 MB

english, 2014

27

Phospholipase D in Cell Signaling: From a Myriad of Cell Functions to Cancer Growth and Metastasis

Gomez-Cambronero, J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.40 MB

english, 2014

28

The Regulatory Roles of MicroRNA-146b-5p and Its Target Platelet-derived Growth Factor Receptor (PDGFRA) in Erythropoiesis and Megakaryocytopoiesis

Zhai, P.-F., Wang, F., Su, R., Lin, H.-S., Jiang, C.-L., Yang, G.-H., Yu, J., Zhang, J.-W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.36 MB

english, 2014

29

Interaction between Ribosome Assembly Factors Krr1 and Faf1 Is Essential for Formation of Small Ribosomal Subunit in Yeast

Zheng, S., Lan, P., Liu, X., Ye, K.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.22 MB

english, 2014

30

Thematic Minireview Series on Phospholipase D and Cancer

Gomez-Cambronero, J., Carman, G. M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 597 KB

english, 2014

31

High Mobility Group Box-1 (HMGB1) Participates in the Pathogenesis of Alcoholic Liver Disease (ALD)

Ge, X., Antoine, D. J., Lu, Y., Arriazu, E., Leung, T.-M., Klepper, A. L., Branch, A. D., Fiel, M. I., Nieto, N.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 8.51 MB

english, 2014

32

Structure of Yin Yang 1 Oligomers That Cooperate with RuvBL1-RuvBL2 ATPases

Lopez-Perrote, A., Alatwi, H. E., Torreira, E., Ismail, A., Ayora, S., Downs, J. A., Llorca, O.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.03 MB

english, 2014

33

-Agonist-mediated Relaxation of Airway Smooth Muscle Is Protein Kinase A-dependent

Morgan, S. J., Deshpande, D. A., Tiegs, B. C., Misior, A. M., Yan, H., Hershfeld, A. V., Rich, T. C., Panettieri, R. A., An, S. S., Penn, R. B.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

34

The Unfolded Protein Response and the Phosphorylations of Activating Transcription Factor 2 in the trans-Activation of il23a Promoter Produced by -Glucans

Rodriguez, M., Domingo, E., Alonso, S., Frade, J. G., Eiros, J., Crespo, M. S., Fernandez, N.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.65 MB

english, 2014

35

CRL4Cdt2 E3 Ubiquitin Ligase and Proliferating Cell Nuclear Antigen (PCNA) Cooperate to Degrade Thymine DNA Glycosylase in S Phase

Shibata, E., Dar, A., Dutta, A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

36

DNA Damage to a Single Chromosome End Delays Anaphase Onset

Silva, B. A., Stambaugh, J. R., Yokomori, K., Shah, J. V., Berns, M. W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.20 MB

english, 2014

37

A Coding IRAK2 Protein Variant Compromises Toll-like receptor (TLR) Signaling and Is Associated with Colorectal Cancer Survival

Wang, H., Flannery, S. M., Dickhofer, S., Huhn, S., George, J., Kubarenko, A. V., Lascorz, J., Bevier, M., Willemsen, J., Pichulik, T., Schafmayer, C., Binder, M., Manoury, B., Paludan, S. R., Alarcon

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.37 MB

english, 2014

38

Inhibition of Hyaluronan Synthesis Protects against Central Nervous System (CNS) Autoimmunity and Increases CXCL12 Expression in the Inflamed CNS

Mueller, A. M., Yoon, B. H., Sadiq, S. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.83 MB

english, 2014

39

LPS Induces the Degradation of Programmed Cell Death Protein 4 (PDCD4) to Release Twist2, Activating c-Maf Transcription to Promote Interleukin-10 Production

van den Bosch, M. W. M., Palsson-Mcdermott, E., Johnson, D. S., O'Neill, L. A. J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.01 MB

english, 2014

40

Molecular Insights of p47phox Phosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

Meijles, D. N., Fan, L. M., Howlin, B. J., Li, J.-M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.96 MB

english, 2014

41

Cystathionine -Synthase (CBS) Domains Confer Multiple Forms of Mg2+-dependent Cooperativity to Family II Pyrophosphatases

Salminen, A., Anashkin, V. A., Lahti, M., Tuominen, H. K., Lahti, R., Baykov, A. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.91 MB

english, 2014

42

The Serotonin Transporter Undergoes Constitutive Internalization and Is Primarily Sorted to Late Endosomes and Lysosomal Degradation

Rahbek-Clemmensen, T., Bay, T., Eriksen, J., Gether, U., Jorgensen, T. N.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.26 MB

english, 2014

43

Curcumin inhibits Rift Valley fever virus replication in human cells.

Narayanan, A., Kehn-Hall, K., Senina, S., Lundberg, L., Van Duyne, R., Guendel, I., Das, R., Baer, A., Bethel, L., Turell, M., Hartman, A. L., Das, B., Bailey, C., Kashanchi, F.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 503 KB

english, 2014

44

Functional Antagonism between High Temperature Requirement Protein A (HtrA) Family Members Regulates Trophoblast Invasion

Chen, Y.-Y., Chuang, P.-Y., Chen, C.-P., Chiu, Y.-H., Lo, H.-F., Cheong, M.-L., Huang, J.-Y., Kuo, P.-L., Chen, H.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.15 MB

english, 2014

45

Response Gene to Complement 32 Protein Promotes Macrophage Phagocytosis via Activation of Protein Kinase C Pathway

Tang, R., Zhang, G., Chen, S.-Y.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.32 MB

english, 2014

46

The Subfamily-specific Assembly of Eag and Erg K+ Channels Is Determined by Both the Amino and the Carboxyl Recognition Domains

Lin, T.-F., Lin, I.-W., Chen, S.-C., Wu, H.-H., Yang, C.-S., Fang, H.-Y., Chiu, M.-M., Jeng, C.-J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 7.61 MB

english, 2014

47

Actin Enables the Antimicrobial Action of LL-37 Peptide in the Presence of Microbial Proteases

Sol, A., Skvirsky, Y., Nashef, R., Zelentsova, K., Burstyn-Cohen, T., Blotnick, E., Muhlrad, A., Bachrach, G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.44 MB

english, 2014

48

B-Raf Regulation of Integrin 4 1-mediated Resistance to Shear Stress through Changes in Cell Spreading and Cytoskeletal Association in T Cells

Brown, W. S., Khalili, J. S., Rodriguez-Cruz, T. G., Lizee, G., McIntyre, B. W.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.29 MB

english, 2014

49

Thymine DNA Glycosylase Is a CRL4Cdt2 Substrate

Slenn, T. J., Morris, B., Havens, C. G., Freeman, R. M., Takahashi, T. S., Walter, J. C.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.30 MB

english, 2014

50

Depletion of Cyclophilins B and C Leads to Dysregulation of Endoplasmic Reticulum Redox Homeostasis

Stocki, P., Chapman, D. C., Beach, L. A., Williams, D. B.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

51

Glycosylation and Cross-linking in Bone Type I Collagen

Terajima, M., Perdivara, I., Sricholpech, M., Deguchi, Y., Pleshko, N., Tomer, K. B., Yamauchi, M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.51 MB

english, 2014

52

CX3CR1(+) B Cells Show Immune Suppressor Properties

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

53

The N-terminal Domain Allosterically Regulates Cleavage and Activation of the Epithelial Sodium Channel

Kota, P., Buchner, G., Chakraborty, H., Dang, Y. L., He, H., Garcia, G. J. M., Kubelka, J., Gentzsch, M., Stutts, M. J., Dokholyan, N. V.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.40 MB

english, 2014

54

CREPT/RPRD1B, a Recently Identified Novel Protein Highly Expressed in Tumors, Enhances the -Catenin{middle dot}TCF4 Transcriptional Activity in Response to Wnt Signaling

Zhang, Y., Liu, C., Duan, X., Ren, F., Li, S., Jin, Z., Wang, Y., Feng, Y., Liu, Z., Chang, Z.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.97 MB

english, 2014

55

Long Term Ablation of Protein Kinase A (PKA)-mediated Cardiac Troponin I Phosphorylation Leads to Excitation-Contraction Uncoupling and Diastolic Dysfunction in a Knock-in Mouse Model of Hypertrophic Cardiomyopathy

Dweck, D., Sanchez-Gonzalez, M. A., Chang, A. N., Dulce, R. A., Badger, C.-D., Koutnik, A. P., Ruiz, E. L., Griffin, B., Liang, J., Kabbaj, M., Fincham, F. D., Hare, J. M., Overton, J. M., Pinto, J. R

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.21 MB

english, 2014

56

Ubiquitin-specific Peptidase 20 Regulates Rad17 Stability, Checkpoint Kinase 1 Phosphorylation and DNA Repair by Homologous Recombination

Shanmugam, I., Abbas, M., Ayoub, F., Mirabal, S., Bsaili, M., Caulder, E. K., Weinstock, D. M., Tomkinson, A. E., Hromas, R., Shaheen, M.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.03 MB

english, 2014

57

Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells

Harjes, U., Bridges, E., McIntyre, A., Fielding, B. A., Harris, A. L.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.12 MB

english, 2014

58

Epigenetic Modulation of Intestinal Cholesterol Transporter Niemann-Pick C1-like 1 (NPC1L1) Gene Expression by DNA Methylation

Malhotra, P., Soni, V., Kumar, A., Anbazhagan, A. N., Dudeja, A., Saksena, S., Gill, R. K., Dudeja, P. K., Alrefai, W. A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.80 MB

english, 2014

59

Engagement of Nucleotide-binding Oligomerization Domain-containing Protein 1 (NOD1) by Receptor-interacting Protein 2 (RIP2) Is Insufficient for Signal Transduction

Mayle, S., Boyle, J. P., Sekine, E., Zurek, B., Kufer, T. A., Monie, T. P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 5.55 MB

english, 2014

60

A Structural and Biochemical Model of Processive Chitin Synthesis

Dorfmueller, H. C., Ferenbach, A. T., Borodkin, V. S., van Aalten, D. M. F.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.28 MB

english, 2014