Volume 17; Issue 4

Journal of Biomolecular Screening

Volume 17; Issue 4

1

Fragment-Based Screening for Inhibitors of PDE4A Using Enthalpy Arrays and X-ray Crystallography

Recht, M. I., Sridhar, V., Badger, J., Hernandez, L., Chie-Leon, B., Nienaber, V., Torres, F. E.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 773 KB

english, 2012

2

Development of a High-Throughput Screening Method for LIM Kinase 1 Using a Luciferase-Based Assay of ATP Consumption

Mezna, M., Wong, A. C., Ainger, M., Scott, R. W., Hammonds, T., Olson, M. F.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

3

A Human Islet Cell Culture System for High-Throughput Screening

Walpita, D., Hasaka, T., Spoonamore, J., Vetere, A., Takane, K. K., Fomina-Yadlin, D., Fiaschi-Taesch, N., Shamji, A., Clemons, P. A., Stewart, A. F., Schreiber, S. L., Wagner, B. K.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 870 KB

english, 2012

4

Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor

Ungermannova, D., Parker, S. J., Nasveschuk, C. G., Chapnick, D. A., Phillips, A. J., Kuchta, R. D., Liu, X.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 973 KB

english, 2012

5

Phaedra, a Protocol-Driven System for Analysis and Validation of High-Content Imaging and Flow Cytometry

Cornelissen, F., Cik, M., Gustin, E.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

6

Hypothesis Testing in High-Throughput Screening for Drug Discovery

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 735 KB

english, 2012

7

Development of a Novel Fluorescence Polarization-Based Assay for Studying the -Catenin/Tcf4 Interaction

Tian, W., Xu, Y., Han, X., Duggineni, S., Han, X., Huang, Z., An, J.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 410 KB

english, 2012

8

Identification of Novel Compounds That Increase SMN Protein Levels Using an Improved SMN2 Reporter Cell Assay

Cherry, J. J., Evans, M. C., Ni, J., Cuny, G. D., Glicksman, M. A., Androphy, E. J.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 904 KB

english, 2012

9

Microplates, Assay Reagents, Screening Consumables, and Kits

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 428 KB

english, 2012

10

Identification of Influenza Virus Inhibitors Targeting NS1A Utilizing Fluorescence Polarization-Based High-Throughput Assay

Cho, E. J., Xia, S., Ma, L.-C., Robertus, J., Krug, R. M., Anslyn, E. V., Montelione, G. T., Ellington, A. D.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 841 KB

english, 2012

11

A Mechanism-Based Whole-Cell Screening Assay to Identify Inhibitors of Protein Export in Escherichia coli by the Sec Pathway

Crowther, G. J., Quadri, S. A., Shannon-Alferes, B. J., Van Voorhis, W. C., Rosen, H.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 967 KB

english, 2012

12

A New Approach to Drug Discovery: High-Throughput Screening of Microbial Natural Extracts against Aspergillus fumigatus Using Resazurin

Monteiro, M. C., de la Cruz, M., Cantizani, J., Moreno, C., Tormo, J. R., Mellado, E., De Lucas, J. R., Asensio, F., Valiante, V., Brakhage, A. A., Latge, J.-P., Genilloud, O., Vicente, F.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

13

Optimization of Fluorescently Labeled Nrf2 Peptide Probes and the Development of a Fluorescence Polarization Assay for the Discovery of Inhibitors of Keap1-Nrf2 Interaction

Inoyama, D., Chen, Y., Huang, X., Beamer, L. J., Kong, A.-N. T., Hu, L.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 565 KB

english, 2012