Volume 12; Issue 4

Journal of Medicinal Chemistry

Volume 12; Issue 4

1

Cyclic disulfides. III. (-)-(S)-1,2-dithiepan-4-amine and related compounds

Herbrandson, H. F., Wood, Rebecca H.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 778 KB

english, 1969

2

Isoxazole chemistry. I. 3- or 5-(5-Nitro-2-furyl)-5- or -3-methylisoxazoles

Micetich, Ronald G.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 591 KB

english, 1969

3

.beta.-Adrenergic blocking agents. V. 1-Amino-3-(substituted phenoxy)-2-propanols

Crowther, Albert F., Gilman, D. J., McLoughlin, B. J., Smith, Leslie Harold, Turner, R. W., Wood, T. M.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 482 KB

english, 1969

4

Tetracyclic phenothiazines. II. Antibacterial evaluation of 3-oxo-3H-pyrido[3,2,1-kl]phenothiazine-2-carboxylate

Huang, Te-Sheng, Yale, Timothy J., Martin, Arnold R.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 381 KB

english, 1969

5

Repository drugs. VIII. Ester and amide congeners of amodiaquine, hydroxychloroquine, oxychloroquine, primaquine, quinacrine, and related substances as potential long-acting antimalarial agents

Elslager, Edward F., Tendick, Frank H., Werbel, Leslie M.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 937 KB

english, 1969

6

Antimalarial compounds related to diaminodiphenyl sulfone

Bader, Henry, Hoops, John F., Biel, John H., Koelling, Harlen H., Stein, Robert G., Singh, Tara

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 353 KB

english, 1969

7

Synthesis and analgetic activity of some 1-substituted 3-pyrrolidinylanilides and dihydrobenzoxazinones

Helsley, Grover C., Lunsford, Carl D., Welstead, William J., Boswell, Robert F., Funderburk, William H., Johnson, David N.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 434 KB

english, 1969

8

Biologically oriented organic sulfur chemistry. II. Formation of hemimercaptals or hemimercaptoles (.alpha.-hydroxy sulfides) as a means of latentiating thiols

Field, Lamar, Sweetman, B. J., Bellas, Michael

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 681 KB

english, 1969

9

2-(.omega.-Aminoalkyl)-4-tert-butyl-6-phenylphenols as antimalarial agents

Duncan, Warren G., Henry, David W.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 286 KB

english, 1969

10

Irreversible enzyme inhibitors. CLVII. Effect of bridge modification on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. I

Baker, Bernard Randall, Vermeulen, Nicolaas M. J.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 503 KB

english, 1969

11

Heterocyclic mesoionic structures, a novel class of monoamine oxidase inhibitors. II. Arylanhydro-1,2,3-thiadiazolium hydroxides

Wiseman, Edward H., Cameron, Donald P.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 656 KB

english, 1969

12

9-(4-Aminobenzylidene)fluorenes

Bahner, Carl T., Brotherton, David H.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 273 KB

english, 1969

13

Thyroxine analogs. XVII. 3,5-Bis(ethylthio)- and 3,5-bis(phenylthio)-DL-thyronines and their 3'-isopropyl analogs

Jorgensen, Eugene C., Muhlhauser, Richard O., Wiley, Robert A.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 399 KB

english, 1969

14

Two Views of Drug Abuse. II. Drug Abuse. A Course for Educators

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 81 KB

english, 1969

15

Iodinated derivatives of histamine and N-acetylhistamine

Tominaga, Mineko, Paiva, Antonio C. M.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 314 KB

english, 1969

16

Anabolic Steroids

Counsell, Raymond

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 186 KB

english, 1969

17

Nitrones. I. .alpha.-(5-Nitro-2-furyl)-N-arylnitrones

Kim, H. K., Bambury, R. E.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 249 KB

english, 1969

18

Sulfamoylbenzoic acid ester derivatives as potential local anesthetics. I

Sharghi, N., Lalezari, I., Niloofari, G., Golgolab, H.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 285 KB

english, 1969

19

Conformation of some 1-azabicycloalkanols

Lingard, R. G., Beckett, Arnold H., Theobald, A. E. E.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 638 KB

english, 1969

20

Bacteriostatic effectiveness of 1-acyl-3-(3,4-dichlorophenyl)ureas

Zakaria, Moneeb H., Taber, David

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 234 KB

english, 1969

21

(Carboxymethyl)cyclohexyldimethylammonium chloride hydrazide

McGuire, T. A., Mehltretter, C. L.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 144 KB

english, 1969

22

Benzylideneindenes with oxygen attached to the indene ring

Bahner, Carl T., Brotherton, David H., Kinder, Harold

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 272 KB

english, 1969

23

Analgetic activity of cyclized basic anilides

Havera, Herbert J., VanDyke, J. W., Liu, T. M. H., Sancilio, L. F.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 363 KB

english, 1969

24

N4,N4'-Decamethylenebis(4-aminopyridine) and N9,N9'-decamethylenebis(9-aminoacridine)

Paolini, John P., Lendvay, Louis J., Palopoli, Frank P.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 271 KB

english, 1969

25

Potential antiradiation agents. II. Guanidinoalkanethiosulfuric acids

Klayman, Daniel L., Grenan, Marie M., Jacobus, David P.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 385 KB

english, 1969

26

Purine nucleosides. XXV. Synthesis of certain derivatives of 5'-amino-5'-deoxy- and 5'-amino-2',5'-dideoxy-.beta.-D-ribofuranosylpurines as purine nucleotide analogs

Stout, Mason G., Robins, Morris J., Olsen, Richard K., Robins, Roland K.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 728 KB

english, 1969

27

.beta.-Adrenergic blocking agents. VI. Pronethalol and propranolol analogs with alkyl substituents in the alkanol side chain

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 572 KB

english, 1969

28

Cyclic disulfides. II. 1,2-Dithiepan-5-amine

Herbrandson, H. F., Wood, Rebecca H.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 597 KB

english, 1969

29

Irreversible enzyme inhibitors. CLVI. Proteolytic enzymes. XII. Inhibitors of guinea pig complement derived by quaternization of 3-acylamidopyridines with .alpha.-bromomethylbenzenesulfonyl fluorides

Baker, Bernard Randall, Hurlbut, Jeffrey A.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 408 KB

english, 1969

30

Masthead

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 106 KB

english, 1969

31

2-Benzyl-5-(dimethylamino)-.gamma.-valerolactone, an inhibitor of plasma cholinesterase

Smith, Sherrel C., Dunn, Floyd W.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 166 KB

english, 1969

32

Preparation and antibacterial activity of .alpha.-(5-tetrazolyl)benzylpenicillin

Essery, John M.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 417 KB

english, 1969

33

Purine N-oxides. XXIX. Synthesis of 6-(hydroxyamino)purine 3-oxide and related derivatives

Giner-Sorolla, Alfredo

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 406 KB

english, 1969

34

Synthesis of certain 3,5-dimethyl-N1-(arylsulfonyl)pyrazoles and 3-methyl-N1-(arylsulfonyl)-5-pyrazolones

Sunkel, Carlos, Sanchez, Mariana

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 279 KB

english, 1969

35

Steric parameters in drug design. Monoamine oxidase inhibitors and antihistamines

Kutter, Eberhard, Hansch, Corwin

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 721 KB

english, 1969

36

1-Adamantanecarboxylic acid ester of scopolamine

Moffett, Robert B.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 135 KB

english, 1969

37

Tricyclic analogs of melatonin

Kobayashi, T., Spande, T. F., Aoyagi, H., Witkop, Bernhard

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 357 KB

english, 1969

38

Irreversible enzyme inhibitors. CLV. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 1-[4-.omega.-aminoalkoxy)-3-chlorophenyl]-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazines bearing a terminal sulfonyl fluoride

Baker, Bernard Randall, Janson, Eunice E.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 513 KB

english, 1969

39

Proving New Drugs-A Guide to Clinical Trials

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 186 KB

english, 1969

40

Thia steroids. I. 2-Thia-A-nor-5.alpha.-androstan-17.beta.-ol, an active androgen

Wolff, Manfred E., Zanati, Galal

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 410 KB

english, 1969

41

Repository drugs. VI. 4'-[N-(Aralkylidene-, -benzylidene-, and-naphthylidene)sulfanilyl]anilides, 4'-[N-[(dimethylamino)methylene]sulfanilyl]anilides, and related sulfanilylanilides with prolonged antimalarial and antileprotic action

Worth, Donald F., Elslager, Edward F., Phillips, Annette A.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 649 KB

english, 1969

42

Comparison of schistosomicidal activity of xanthenones and 4-methyl-3-chloroanilines and their hydroxymethyl analogs in Swiss mice and Syrian hamsters infected with Schistosma mansoni

Berberian, Dicran A., Dennis, Emery W., Freele, Hugh W., Rosi, David, Lewis, Thomas Richard, Lorenz, Roman R., Archer, Sydney

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 366 KB

english, 1969

43

Irreversible enzyme inhibitors. CLIV. Some factors in cell wall transport of active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 5-substituted 2,4-diaminopyrimidines

Baker, Bernard Randall, Meyer, Rich B.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 489 KB

english, 1969

44

Structure-activity studies of 3,4,5-trimethoxybenzamides. I. Variation of the amine function

Skinner, Wilfred A., Kennedy, J., DeGraw, Joseph I., Johnson, Howard

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 354 KB

english, 1969

45

Dihydrofolate reductase from Trypanosoma equiperdum. II. Inhibition by 2,4-diaminopyrimidines and related heterocycles

McCormack, John J., Jaffe, Julian J.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 919 KB

english, 1969

46

Progress in Drug Research. Volume 12

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 254 KB

english, 1969

47

Synthesis and progestational activity of some 1,2.alpha.-cyclomethylene-16-methylene progesterone derivatives

Shapiro, Elliot L., Popper, T. L., Weber, Lois, Neri, R., Herzog, H. L.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 720 KB

english, 1969

48

3,3-Disubstituted ethyl carbazates

Smith, Walter Thomas, Chen, Wen-Yean

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 262 KB

english, 1969

49

N1-Sulfato-N2-isonicotinoylhydrazine. A potential metabolite of isoniazid

Peters, John Henry

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 263 KB

english, 1969

50

Irreversible enzyme inhibitors. CLVIII. Effect of bridge modification on the selective irreversible inhibition of a dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. II

Baker, Bernard Randall, Vermeulen, Nicolaas M. J.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 443 KB

english, 1969

51

Bridgehead nitrogen compounds as potential analgetics

Beckett, Arnold H., Lingard, R. G., Theobald, A. E. E.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 775 KB

english, 1969

52

Synthesis and biological activity of certain 8-mercaptopurine and 6-mercaptopyrimidine S-nucleosides

Shuman, Dennis A., Bloch, Alexander, Robins, Roland K., Robins, Morris J.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 612 KB

english, 1969

53

Repository drugs. VII. N-Allylidene-4,4'-sulfonyldianiline and N-(benzylidene- and -1-naphthylmethylene)-N'-methylene-4,4'-sulfonyldianiline polymers with prolonged antimalarial and antileprotic action

Elslager, Edward F., Capps, David B., Worth, Donald F.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 372 KB

english, 1969

54

Synthesis of heterocyclic compounds. CCLXXXXV. Syntheses of benzomorphan and related compounds. II. The debenzylation of quaternary ammonium salts with thiophenol

Kametani, Tetsuji, Kigasawa, Kazuo, Hiiragi, Mineharu, Wagatsuma, Nagatoshi, Wakisaka, Kikuo, Kusama, O.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 390 KB

english, 1969

55

Two Views of Drug Abuse. 1. Amphetamine Abuse

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 81 KB

english, 1969

56

Tetrahydroisoquinolines. I. Preparation and analgetic activity of some 1-[2-(phenylthio)ethyl]tetrahydroisoquinolines and 1-(2-phenoxyethyl)tetrahydroisoquinolines

Montzka, Thomas A., Cladel, Nancy M., Matiskella, John D.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 505 KB

english, 1969

57

Synthesis and antiviral properties of 1-adamantylguanidine. A modified method for preparing tert-alkylguanidines

Geluk, H. W., Schut, J., Schlatmann, J. L. M. A.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 517 KB

english, 1969

58

Inhibition of cholesterolgenesis in vitro by chlorophenoxyacetic acids. Effect of .alpha.-methyl groups

Witiak, Donald T., Hackney, Robert E., Whitehouse, Michael W.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 381 KB

english, 1969

59

Superdelocalizability and charge density. A correlation with partition coefficients

Rogers, Kenneth S., Cammarata, Arthur

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 298 KB

english, 1969

60

2-Benzyl-5-aminolevulinic acid, an analog of glycyl-DL-phenylalanine

Smith, Sherrel C., Dunn, Floyd W.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 289 KB

english, 1969

61

Terpene compounds as drugs. VI. Acyclic mono- and sesquiterpene thiocyanates and isothiocyanates

Pala, Gianfranco, Mantegani, Antonio, Coppi, Germano

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 293 KB

english, 1969

62

6-(Dimethylamino)chrysene and other analogs of 4-(4-dimethylamino)stilbene

Bahnr, Carl T., Brotherton David H.,, Kinder, Harold, Rich, William, Watson, Stuart L., Zirkle, John

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 153 KB

english, 1969

63

Nitroheterocycles. I. Nitrofuryl-substituted 3-amino-1,2,4-oxadiazoles and 5-amino-1,2,4-oxadiazoles

Breuer, Hermann

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 251 KB

english, 1969

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