Volume 29; Issue suppl_10

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Annals of Oncology
Volume 29; Issue suppl_10

Annals of Oncology

Volume 29; Issue suppl_10

1

26PLymphotoxin alpha functional germline genetic variant: A future prognostic factor in colorectal cancer?

Rocha, M S, Pinheiro, F, Cardoso, B, Del Rio, M, Lojo Teira, A, Pires, M, Bastos, E, Ribeiro, R

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

2

31OT cell therapy with EBV-specific cytotoxic T-lymphocytes for patients with nasopharyngeal carcinoma

Pedrazzoli, P, Comoli, P, Secondino, S, Gurrado, A, Pagani, A, Zecca, M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 87 KB

english, 2018

3

12PMSI status plus immunoscore to select metastatic colorectal cancer patients for immunotherapies

Galon, J, Mlecnik, B, Hermitte, F, Marliot, F, Bifulco, C, Lugli, A, Nagtegaal, I D, Hartmann, A, van den Eynde, M, Roehrl, M, Ohashi, P, Zavadova, E, Torigoe, T, Patel, P, Wang, Y, Kawakami, Y, Marin

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

4

LBA2Proton pump inhibitors negatively impact survival of PD-1 inhibitor based therapies in metastatic melanoma patients

Homicsko, K, Richtig, G, Tuchmann, F, Tsourti, Z, Hanahan, D, Coukos, G, Wind-Rotolo, M, Richtig, E, Zygoura, P, Holler, C, Dafni, U, Michielin, O A

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 90 KB

english, 2018

5

33OAnti-MUC1 CAR-T cells combined with PD-1 knockout engineered T cells for patients with non-small cell lung cancer (NSCLC): A pilot study

Chen, S, Lin, Y, Zhong, S, An, H, Lu, Y, Yin, M, Liang, W, McGowan, E M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 86 KB

english, 2018

6

48TiPA phase II study of autologous tumor infiltrating lymphocytes (TIL; LN-144/LN-145) in patients with solid tumors

Chesney, J, Cacovean, A, Li, H, Barton, D, Fardis, M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

7

54PIncidence of programmed cell death 1 inhibitor-related diarrhea in patients with advanced cancer: A systematic review and meta-analysis

Sui, J-D, Wang, Y, Wan, Y, Wu, Y-Z

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

8

69OA small molecule human PD-1/PD-L1 inhibitor promotes T cell immune activation and reduces tumor growth in a preclinical model

Vilalta Colomer, M, Punna, S, Li, S, Malathong, V, Lange, C, McMurtrie, D, Yang, J, Roth, H, McMahon, J, Campbell, J J, Ertl, L S, Ong, R, Wang, Y, Zhao, N, Yau, S, Dang, T, Zhang, P, Schall, T J, Sin

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 102 KB

english, 2018

9

25PUnsupervised analysis of the extent, organization and phenotype of tumor-infiltrating lymphocytes in breast cancer identifies two major clusters

Solinas, C, Richard, F, Garaud, S, De Silva, P, de Wind, A, Van Den Eyden, G, Gu-Trantien, C, Langouo Fontsa, M, Noël, G, Boisson, A, Naveaux, C, Duvillier, H, Craciun, L, Larsimont, D, Willard-Gallo,

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

10

1OAdvanced CT imaging features reflect distinct tissue immune profiles and exhibit high prognostic impact on NSCLC

Mazzaschi, G, Pagano, P, Milanese, G, Madeddu, D, Falco, A, Armani, G, Bocchialini, G, Marturano, D, Ampollini, L, Lorusso, B, Lagrasta, C, Sverzellati, N, Silva, M, Tiseo, M, Quaini, F, Roti, G

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 93 KB

english, 2018

11

97PCirculating RNAs in advanced colorectal cancer patients reveal increased expression of PD-1 with conventional CRC therapy

Nasrullah, M, Bakhrebah, M A, Hassan, M A, Alghamdi, A, Abdulaal, W H, Zamzami, M A, Ghafari, A A-G, Khan, M I, Choudhry, H

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 78 KB

english, 2018

12

36PCAR-modified natural killer cell line expressing CD47/SIRPa blockers as a combined approach for solid cancer therapy

Chikaev, A, Gorchakov, A, Kulemzin, S, Belovezhets, T, Matvienko, D, Volkova, O, Taranin, A

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

13

61PThe real-world impact of cancer immunotherapy on the survival of patients with metastatic melanoma

Donia, M, Ellebaek, E, Oellegaard, T H, Duval, L, Aaby, J B, Hoejberg, L, Koehler, U H, Schmidt, H, Bastholt, L, Svane, I-M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 85 KB

english, 2018

14

63PA network meta-analysis of the frontline immune-checkpoint inhibitor-based regimens in advanced non-small cell lung cancer

Kattan, J G, Rassy, E E, Bakouny, Z, Assi, T, Pavlidis, N

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 76 KB

english, 2018

15

89PPre-clinical evaluation of bifunctional SIRPα-antibody fusion proteins for the treatment of acute myeloid leukemia

Pascual Ponce, L, Heitmüller, C, Kozik, J-H, Subklewe, M, Fenn, N C, Hopfner, K-P

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 82 KB

english, 2018

16

94PIncreased antitumour activity and extravasation of immune checkpoint inhibitor due to hyaluronidase expressed from oncolytic adenovirus VCN-01 and generation of new viruses with improved hyaluronidase activity

Farrera, M, Mato-Berciano, A, Morgado, S, Moreno, R, de Sostoa Pomes, J, Alemany, R, Bazan-Peregrino, M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 92 KB

english, 2018

17

95PTargeting the tumor stroma with a bispecific T-cell engager-armed oncolytic adenovirus

de Sostoa Pomés, J, Fajardo, C A, Moreno, R, Ramon, M D, Farrera Sal, M, Alemany, R

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 79 KB

english, 2018

18

100PBalancing the efficacy and toxicity of anti-CD47 antibodies by direct screening in humanized mouse models

Li, Y, Gan, T, Guo, Y, Shen, Y, Yang, Y, Ni, J

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 76 KB

english, 2018

19

20PDynamic of systemic immunity and its impact on tumor recurrence after radiofrequency ablation of hepatocellular carcinoma

Rochigneux, P, Nault, J C, Ganne-Carrié, N, Olive, D

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 78 KB

english, 2018

20

LBA6Durvalumab with or without tremelimumab vs platinum-based chemotherapy as first-line treatment for metastatic non-small cell lung cancer: MYSTIC

Rizvi, N A, Chul Cho, B, Reinmuth, N, Lee, K H, Ahn, M-J, Luft, A, van den Heuvel, M, Cobo, M, Smolin, A, Vicente, D, Moiseyenko, V, Antonia, S J, Le Moulec, S, Robinet, G, Natale, R, Nakagawa, K, Zha

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 94 KB

english, 2018

21

11PA SNP germinal signature for predicting checkpoint inhibitor treatment outcome

Milano, G, Refae, S, Gal, J, Ebran, N, Otto, J, Shell, S, Everts, R, Chamorey, E, Saada-Bouzid, E

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

22

104PPIG-C and SOCS3: Potential immunotargets regulated by non-coding RNAs in TNBC

Armanios, M M, Abdel Tawab, R, El Tayebi, H M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 76 KB

english, 2018

23

LBA1Fast progression in patients treated with a checkpoint inhibitor (cpi) vs chemotherapy in OAK, a phase III trial of atezolizumab (atezo) vs docetaxel (doc) in 2L+ NSCLC

Gandara, D R, Reck, M, Morris, S, Cardona, A, Mendus, D, Ballinger, M, Rittmeyer, A

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 101 KB

english, 2018

24

22PPD-L1 microSPECT/CT imaging for longitudinal monitoring of PD-L1 expression in syngeneic and humanized mouse models for cancer

Heskamp, S, Verhoeff, S R, Wierstra, P J, Molkenboer-Kuenen, J D M, Sandker, G W, Thordardottir, S, Olive, D, Bussink, J, Boerman, O C, Dolstra, H, Aarntzen, E H J G, Hobo, W A

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 78 KB

english, 2018

25

9PIdentification of serum microRNAs predicting the response to nivolumab in patients with advanced gastric cancer

Miyamoto, T, Kato, K, Matsuzaki, J, Takizawa, S, Sudo, K, Shoji, H, Iwasa, S, Honma, Y, Takashima, A, Okita, N, Sakamoto, H, Boku, N, Takahiro, O

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 76 KB

english, 2018

26

68OLigand-inducible, prostate stem cell antigen (PSCA)-directed GoCAR-T™ cells in advanced solid tumors: Preliminary results from a dose escalation study

Becerra, C R, Hoof, P, Paulson, S, Manji, G A, Gardner, O, Malankar, A, Shaw, J, Blass, D, Ballard, B, Yi, X, Anumula, M, Foster, A, Senesac, J, Woodard, P

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 102 KB

english, 2018

27

28TiPCHECK'UP: A prospective cohort study to identify predictive factors of response and mechanisms of resistance to PD-1 and PD-L1 antagonists

Penault-Llorca, F, Caux, C, Depil, S, Le Tourneau, C, Pérol, M, Robert, C, Soumelis, V, Couch, D, Isambert, N, Fernandez, Y, Filleron, T, Vassal, G

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 73 KB

2018

28

2OSomatic mutations in BRCA2, NFE2L2, ARID1A and NOTCH1 sensitize to anti-PDL1 therapy in multiple tumor types

Kuziora, M, Si, H, Higgs, B, Brohawn, P, Streicher, K, Jure-Kunkel, M, Raja, R, Helman, E, Franovic, A, Cooper, Z, Shrestha, Y, Holoweckyj, N, Lee, Y, Achour, I, Ye, J, Mukhopadhyay, P, Dennis, P A, M

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 94 KB

2018

29

76PTislelizumab, an anti-PD-1 antibody, in patients with urothelial carcinoma (UC): Results from an ongoing phase I/II study

Sandhu, S, Hill, A, Gan, H, Friedlander, M, Voskoboynik, M, Barlow, P, Townsend, A, Song, J, Zhang, Y, Liang, L, Desai, J

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

30

70OA phase Ia/Ib trial of tislelizumab, an anti-PD-1 antibody (ab), in patients (pts) with advanced solid tumors

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 114 KB

2018

31

64PPost-progression evaluation of patients treated with nivolumab for advanced non-small cell lung cancer: A prospective cohort analysis

Quaquarini, E, Gervaso, L, Sottotetti, F, Bernardo, A, Palumbo, R, Gambaro, A, Frascaroli, M, Tagliaferri, B, Teragni, C M, Presti, D, Porta, C

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 76 KB

english, 2018

32

35PAnti-human CD117 CAR T-cells efficiently eliminate hematopoietic stem and CD117-positive AML cells

Myburgh, R, Kiefer, J, Russkamp, N, Simonis, A, Pfister, S, Magnani, C, Wilk, M, Müller, A, van den Broek, M, Becher, B, Neri, D, Manz, M G

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

33

71PPhase I study of cemiplimab, a human monoclonal anti-PD-1, in patients with unresectable locally advanced or metastatic cutaneous squamous cell carcinoma (CSCC): Longer follow-up efficacy and safety data

Owonikoko, T K, Papadopoulos, K P, Johnson, M L, Gil Martín, M, Moreno, V, Salama, A K, Calvo, E, Yee, N S, Safran, H, Aljumaily, R, Mahadevan, D, Niu, J, Kal Mohan, K, Li, J, Stankevich, E, Mathias,

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 73 KB

english, 2018

34

21PBaseline total metabolic tumor volume assessed by 18FDG-PET/CT predicts outcome in advanced melanoma patients treated with pembrolizumab

Awada, G, Özdemir, I, Schwarze, J K, Daeninck, E, Gondry, O, Jansen, Y, Seremet, T, Keyaerts, M, Everaert, H, Neyns, B

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 78 KB

english, 2018

35

59PNivolumab treatment in patients with relapsed/refractory HIV-related lymphomas

Rogacheva, Y, Popova, M, Nekrasova, A, Tsygankov, I, Lepik, K, Stelmah, L, Moiseev, I, Bondarenko, S, Mikhaylova, N, Baykov, V, Afanasyev, B

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 82 KB

english, 2018

36

6PPredictive score using clinical and blood biomarkers in advanced non-small cell lung cancer (aNSCLC) patients treated with immunotherapy

Prelaj, A, Rebuzzi, S E, Pizzutilo, P, Montrone, M, Pesola, F, Longo, V, Lapadula, V, Cassano, F, Petrillo, P, Bafunno, D, Varesano, N, Lamorgese, V, Mastrandrea, A, Ricci, D, Catino, A, Domenico, G

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

37

19PSigns of immunosenescence in patients diagnosed with non-small cell lung cancer

Soria Comes, T, Palomar-Abril, V, Martin Ureste, M, Marco Buades, J E, Fernandez Llavador, M J, Garcia Sanchez, J, Cancela Gomez, M D C, Maestu Maiques, I

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

38

76PTislelizumab, an anti-PD-1 antibody, in patients with urothelial carcinoma (UC): Results from an ongoing phase I/II study

Sandhu, S, Hill, A, Gan, H, Friedlander, M, Voskoboynik, M, Barlow, P, Townsend, A, Song, J, Zhang, Y, Liang, L, Desai, J

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

39

70OA phase Ia/Ib trial of tislelizumab, an anti-PD-1 antibody (ab), in patients (pts) with advanced solid tumors

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 114 KB

english, 2018

40

LBA330 months relapse-free survival, overall survival, and long-term toxicity update of (neo)adjuvant ipilimumab (ipi) + nivolumab (nivo) in macroscopic stage III melanoma (OPACIN trial)

Rozeman, E A, Sikorska, K, van de Wiel, B A, Fanchi, L F, Krijgsman, O, van Thienen, H V, Pronk, L M, Broeks, A, Grijpink-Ongering, L, Ter Meulen, S, Bruining, A, Klop, W M C, van Tinteren, H, Peeper,

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 90 KB

english, 2018

41

102PTargeting human CD141+ DC using CLEC9A antibodies for cancer immunotherapy

Masterman, K-A, Pearson, F E, Tullett, K, Haigh, O, Walpole, C, Daraj, G, Lahoud, M H, Leal Rojas, I, Radford, K

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 93 KB

english, 2018

42

29TiPA translational study to discover novel host-related immune-biomarkers for nivolumab (Nivo) in advanced gastric cancer (GC): JACCRO GC-08 (DELIVER trial)

Sunakawa, Y, Muro, K, Nakajima, T E, Kawakami, H, Inoue, E, Matoba, R, Sato, Y, Ichikawa, W, Fujii, M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 73 KB

english, 2018

43

51OFirst-line pembrolizumab monotherapy in metastatic PD-L1 positive non-small cell lung cancer: A real-world analysis of time on treatment in US community oncology practices

Velcheti, V, Chandwani, S, Chen, X, Pietanza, M C, Burke, T

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

44

77PPreliminary results from a phase 1 study of AB122, a programmed cell death-1 (PD-1) inhibitor, in patients with advanced solid malignancies

Seitz, L C, Rieger, A, Berry, W, Ashok, D, Direnzo, D, Jin, L, Lee, S J, Park, A, Piovesan, D, Tan, J B L, Walters, M J, Karakunnel, J

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

45

47PAn investigation into the effects of prior irradiation to the tumour mass on murine TIL expansion

Azizi, A, Cheadle, E, Popple, A, Illidge, T

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 75 KB

english, 2018

46

96PPreliminary pharmacokinetic results from a phase I study of GBR 1302 in patients with HER2 positive cancers

Gudi, G, Ca, V, Gn, S, von Gunten, C, Fluhler, E, Back, J

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 79 KB

english, 2018

47

96PPreliminary pharmacokinetic results from a phase I study of GBR 1302 in patients with HER2 positive cancers

Gudi, G, Ca, V, Gn, S, von Gunten, C, Fluhler, E, Back, J

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 79 KB

2018

48

73PCemiplimab, a human monoclonal anti-PD-1, in patients (pts) with advanced or metastatic hepatocellular carcinoma (HCC): Data from an expansion cohort (EC) in a phase I study

He, A R, Weiss, G J, Falchook, G, Yee, N S, Gil-Martin, M, Shahda, S, Moreno, V, Brana, I, Crittenden, M, Formenti, S, Al-Rajabi, R, Papadopoulos, K P, Pishvaian, M J, Stankevich, E, Feng, M, Li, J, M

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 78 KB

english, 2018

49

50OEffects of antibiotics and proton pump inhibitors in NSCLC patients treated with atezolizumab and docetaxel: Pooled analysis of the OAK and POPLAR trials

Chalabi, M, Cardona, A, Nagarkar, D, Dhawahir Scala, A M, Albert, M, Kok, M, Powles, T B, Herrera, F

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 91 KB

english, 2018

50

99PHarnessing copper in cancer to enhance anti-tumor immune response

Voli, F, Lerra, L, Kimpton, K, Saletta, F, Cirillo, G, Kavallaris, M, Vittorio, O

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 77 KB

english, 2018

51

37PPooling signaling and costimulatory domains in a flexible CARpool design

Springuel, L, Bolsée, J, Velghe, A, Agaugué, S, Gilham, D

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 93 KB

2018

52

45PEffective treatment of nasopharyngeal carcinoma with autologous Epstein-Barr Virus and oncogene–targeted cytotoxic t lymphocytes

Xia, W, Guoying, L, Xiang, Y

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 75 KB

2018

53

53PImmune-related adverse events correlate with clinical outcomes in non-small cell lung cancer (NSCLC) patients treated with nivolumab in the Italian expanded access programme

Baldini, E, Lunghi, A, Cortesi, E, Turci, D, Garassino, M C, Stati, V, Ardizzoni, A, Ricciuti, B, Frassoldati, A, Romano, G, Illiano, A, Verderame, F, Fasola, G, Marchetti, P, Pinto, C, Carteni, G, Sc

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 94 KB

2018

54

55PEfficacy and safety of nintedanib and docetaxel in lung adenocarcinoma patients (pts) following treatment with immune checkpoint inhibitors (ICIs): First interim results of the ongoing non-interventional study VARGADO (NCT02392455)

Grohe, C, Gleiber, W, Haas, S, Mueller-Huesmann, H, Schulze, M, Atz, J, Kaiser, R

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

55

57PThe efficacy and safety of rechallenge with an alternative immune checkpoint inhibitor in metastatic malignant melanoma

Mohamed, A A, Zhang, S, Faust, G

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 91 KB

2018

56

62PFirst-line systemic real-world treatment of patients with advanced/metastatic NSCLC in the UK

Wang, M, Dhokia, P, Menon, S, Martindale, B

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 76 KB

2018

57

66PIs the current healthcare system ready to treat all eligible patients using car t-cell therapies? An analysis of the NHL situation in France

Verrier, T, Sejourne, T, Rose, M, Mitrofan, L M

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 67 KB

2018

58

67PThe predictive value of 18F-FDG PET/CT after ipilimumab for treatment response evaluation in metastatic melanoma patients

Vari, S, Annovazzi, A, Pasqualoni, R, Sciuto, R, Giannarelli, D, Cognetti, F, Ferraresi, V

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 67 KB

2018

59

72PCemiplimab, a human monoclonal anti-PD-1, plus radiotherapy (RT) in advanced non-small cell lung cancer (NSCLC): Results from a phase I expansion cohort (EC 2)

Moreno, V, Gil-Martin, M, Johnson, M L, Aljumaily, R, Lopez Criado, P, Northfelt, D W, Crittenden, M, Jabbour, S, Rosen, L, Garrido, P, Hervás Morón, A, Rietschel, P, Mohan, K K, Li, J, Stankevich, E,

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

60

74PPhase I expansion cohort results of cemiplimab, a human PD-1 monoclonal antibody, in combination with radiotherapy (RT), cyclophosphamide and GM-CSF, in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC)

Babiker, H M, Brana, I, Mahadevan, D, Owonikoko, T K, Calvo, E, Rischin, D, Moreno, V, Papadopoulos, K P, Crittenden, M, Formenti, S, Giralt, J, Garrido, P, Hervás Morón, A, Mohan, K K, Fury, M G, Low

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 80 KB

2018

61

80PAnti-GITR agonist TRX518 in combination with gemcitabine in advanced solid cancers: Preliminary safety and efficacy from a multi-center phase Ib trial

Velcheti, V, Bauer, T, Luke, J, Rixe, O, Bajor, D, Naik, G S, Sirard, C, Davar, D

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 80 KB

2018

62

81POptimizing novel anti-4-1BB antibodies on a in vivo drug screening platform

Yang, Y, Guo, Y, Shen, Y, Ni, J

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 75 KB

2018

63

84PSafety and clinical outcome in patients with microsatellite-stable, metastatic colorectal or pancreatic cancer treated with the CXCL12 inhibitor NOX-A12 in combination with PD-1 checkpoint inhibitor pembrolizumab

Halama, N, Prüfer, U, Frömming, A, Beyer, D, Eulberg, D, Jungnelius, J, Mangasarian, A

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 90 KB

2018

64

85PEvaluation of the safety and the tolerability of durvalumab plus tremelimumab combined with FOLFOX in metastatic colorectal cancer (MEDITREME)

Fumet, J-D, Isambert, N, Hervieu, A, Zanetta, S, Guion, J-F, Hennequin, A, Rederstorff, E, Bertaut, A, Ghiringhelli, F

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 79 KB

2018

65

87PNew clinical data from the DeCidE1 trial: Results on DPX-Survivac, low dose cyclophosphamide (CPA), and epacadostat (INCB024360) in subjects with advanced recurrent epithelial ovarian cancer

Dorigo, O, Oza, A M, Tanyi, J L, Strauss, J, Pejovic, T, Ghamande, S, Ghatage, P, Villella, J, Fiset, S, MacDonald, L D, Torrey, H, Weir, G M, Hrytsenko, O, Stanford, M M, Newton, R, Leopold, L, Rosu,

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 79 KB

2018

66

101PFirst evidence of antitumor activity of ITPP, a novel hypoxia-modifier: Results of a phase Ib trial

Schneider, M A, Limani, P, Linecker, M, Kron, P, Petrosky, H, Pestalozzi, B C, Jetter, A, Graf, R, Humar, B, Lehn, J-M, Clavien, P-A

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

67

105PThe impact of HIPEC on the anticancer immune response

Roth, L, Breuer, E, Gupta, A, Graf, R, Clavien, P-A, Lehmann, K

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 94 KB

2018

68

106POncolysis dominated therapeutic effect of LCMV-GP – pseudotyped vesicular stomatitis virus in a syngeneic lung cancer model

Wollmann, G, Schreiber, L-M, Urbiola, C, Das, K, Spiesschaert, B, Kimpel, J, Heinemann, F, Stierstorfer, B, Müller, P, Petersson, M, Erlmann, P, von Laer, D

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

69

3PDissecting the spatial heterogeneity of single CTCs reveals immune evasion through MAX regulated CCL5 overexpression in hepatocellular carcinoma

Sun, Y, Yang, X-R, Fan, J

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 107 KB

2018

70

5PBaseline CRP predicts severe immune related adverse events

Verheijden, R, Suijkerbuijk, K

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

71

7PMonocyte-to-lymphocye ratio (MLR) and LDH level in metastatic colorectal cancer (mCRC) patients (pts)

Basile, D, Gerratana, L, Corvaja, C, Pelizzari, G, Garattini, S K, Lisanti, C, Bartoletti, M, Bortot, L, Fanotto, V, Ongaro, E, Cortiula, F, Parnofiello, A, Vitale, M G, Da Ros, L, Di Nardo, P, Torris

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

72

10PClinical and laboratory predictors of immune checkpoint inhibitor efficacy in non-small cell lung cancer

Christopoulos, P, Kohlhäufl, J, Bozorgmehr, F, Kuon, J, Schneider, M, Neumann, O, Liersch, S, Heussel, C, Winter, H, Herth, F, Rieken, S, Muley, T, Meister, M, Bischoff, H, Lasitschka, F, Stenzinger,

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 92 KB

2018

73

16PAnalysis of immune checkpoint- and apoptosis-related lymphocyte markers expression and its association with the prevalence of regulatory lymphocyte populations in the establishment of microinvasive cervical carcinoma

Kurmyshkina, O V, Volkova, T O

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 90 KB

2018

74

17PThe prognostic significance of androgen receptor phosphorylation and the immune infiltrate in prostate cancer

Gan, H W G, McAllister, M, Constancio, V, Payne, S, Underwood, M A, Leung, H Y, Edwards, J

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

75

27PReliability of the detection of the mutation burden status by targeted next generation sequencing applying a large gene panel

Pfarr, N, Boxberg, M, Riedmann, K, Jesinghaus, M, Konukiewitz, B, Glimm, H, Jost, P J, Fröhling, S, Weichert, W

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 91 KB

2018

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