Volume 342; Issue 3

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Journal of Pharmacology and Experimental Therapeutics
Volume 342; Issue 3

Journal of Pharmacology and Experimental Therapeutics

Volume 342; Issue 3

1

Durable Pharmacological Responses from the Peptide ShK-186, a Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease

Tarcha, E. J., Chi, V., Munoz-Elias, E. J., Bailey, D., Londono, L. M., Upadhyay, S. K., Norton, K., Banks, A., Tjong, I., Nguyen, H., Hu, X., Ruppert, G. W., Boley, S. E., Slauter, R., Sams, J., Knap

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 862 KB

english, 2012

2

Activation of AMP-Activated Protein Kinase Inhibits the Proliferation of Human Endothelial Cells

Peyton, K. J., Liu, X.-m., Yu, Y., Yates, B., Durante, W.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

3

Differences in Early Acetaminophen Hepatotoxicity between Obese ob/ob and db/db Mice

Aubert, J., Begriche, K., Delannoy, M., Morel, I., Pajaud, J., Ribault, C., Lepage, S., McGill, M. R., Lucas-Clerc, C., Turlin, B., Robin, M.-A., Jaeschke, H., Fromenty, B.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 3.44 MB

english, 2012

4

Warburg Revisited: Regulation of Mitochondrial Metabolism by Voltage-Dependent Anion Channels in Cancer Cells

Maldonado, E. N., Lemasters, J. J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

5

Mitochondrial Dysfunction in Neurodegenerative Diseases

Johri, A., Beal, M. F.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 465 KB

english, 2012

6

Bioenergetic Effects of Mitochondrial-Targeted Coenzyme Q Analogs in Endothelial Cells

Fink, B. D., Herlein, J. A., Yorek, M. A., Fenner, A. M., Kerns, R. J., Sivitz, W. I.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.34 MB

english, 2012

7

Pharmacokinetic/Pharmacodynamic Model of the Testosterone Effects of Triptorelin Administered in Sustained Release Formulations in Patients with Prostate Cancer

Romero, E., Velez de Mendizabal, N., Cendros, J.-M., Peraire, C., Bascompta, E., Obach, R., Troconiz, I. F.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.30 MB

english, 2012

8

15-Deoxy- 12,14-Prostaglandin J2-Glycerol, a Putative Metabolite of 2-Arachidonyl Glycerol and a Peroxisome Proliferator-Activated Receptor Ligand, Modulates Nuclear Factor of Activated T Cells

Raman, P., Kaplan, B. L. F., Kaminski, N. E.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.62 MB

english, 2012

9

Mitochondrial Function and Dysfunction: An Update

Davis, R. E., Williams, M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.23 MB

english, 2012

10

Oxidative Shielding or Oxidative Stress?

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

11

Vaccination with Platelet-Derived Growth Factor B Kinoids Inhibits CCl4-Induced Hepatic Fibrosis in Mice

Hao, Z.-M., Fan, X.-B., Li, S., Lv, Y.-F., Su, H.-Q., Jiang, H.-P., Li, H.-H.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 4.82 MB

english, 2012

12

Phenanthrene Metabolism in Smokers: Use of a Two-Step Diagnostic Plot Approach to Identify Subjects with Extensive Metabolic Activation

Wang, J., Zhong, Y., Carmella, S. G., Hochalter, J. B., Rauch, D., Oliver, A., Jensen, J., Hatsukami, D. K., Upadhyaya, P., Hecht, S. S., Zimmerman, C. L.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 805 KB

english, 2012

13

Hormonal and Chemical Regulation of Paraoxonases in Mice

Cheng, X., Klaassen, C. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 372 KB

english, 2012

14

Transgenic Mouse Models Resistant to Diet-Induced Metabolic Disease: Is Energy Balance the Key?

Gilliam, L. A. A., Neufer, P. D.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 386 KB

english, 2012

15

The Serotonin 2C Receptor Antagonist SB 242084 Exhibits Abuse-Related Effects Typical of Stimulants in Squirrel Monkeys

Manvich, D. F., Kimmel, H. L., Cooper, D. A., Howell, L. L.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

16

Production and Actions of the Anandamide Metabolite Prostamide E2 in the Renal Medulla

Ritter, J. K., Li, C., Xia, M., Poklis, J. L., Lichtman, A. H., Abdullah, R. A., Dewey, W. L., Li, P.-L.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.53 MB

english, 2012

17

Intestinal Transport of Aminopterin Enantiomers in Dogs and Humans with Psoriasis Is Stereoselective: Evidence for a Mechanism Involving the Proton-Coupled Folate Transporter

Menter, A., Thrash, B., Cherian, C., Matherly, L. H., Wang, L., Gangjee, A., Morgan, J. R., Maeda, D. Y., Schuler, A. D., Kahn, S. J., Zebala, J. A.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

18

Glucocorticosteroids and 2-Adrenoceptor Agonists Synergize to Inhibit Airway Smooth Muscle Remodeling

Dekkers, B. G. J., Pehlic, A., Mariani, R., Bos, I. S. T., Meurs, H., Zaagsma, J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

19

An Ex Vivo Perfusion System Emulating In Vivo Conditions in Noncirrhotic and Cirrhotic Human Liver

Schreiter, T., Marquitan, G., Darnell, M., Sowa, J.-P., Brocker-Preuss, M., Andersson, T. B., Baba, H. A., Furch, M., Arteel, G. E., Mathe, Z., Treckmann, J., Gerken, G., Gieseler, R. K., Canbay, A.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 3.95 MB

english, 2012

20

Apparent Inverse Relationship between Cannabinoid Agonist Efficacy and Tolerance/Cross-Tolerance Produced by 9-Tetrahydrocannabinol Treatment in Rhesus Monkeys

Hruba, L., Ginsburg, B. C., McMahon, L. R.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 246 KB

english, 2012

21

-Opioid Mechanisms for ADL5747 and ADL5859 Effects in Mice: Analgesia, Locomotion, and Receptor Internalization

Nozaki, C., Le Bourdonnec, B., Reiss, D., Windh, R. T., Little, P. J., Dolle, R. E., Kieffer, B. L., Gaveriaux-Ruff, C.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 3.72 MB

english, 2012

22

Quantification of Hepatic UDP Glucuronosyltransferase 1A Splice Variant Expression and Correlation of UDP Glucuronosyltransferase 1A1 Variant Expression with Glucuronidation Activity

Jones, N. R., Sun, D., Freeman, W. M., Lazarus, P.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

23

The Antinociceptive Effects of Nicotinic Partial Agonists Varenicline and Sazetidine-A in Murine Acute and Tonic Pain Models

AlSharari, S. D., Carroll, F. I., McIntosh, J. M., Damaj, M. I.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1017 KB

english, 2012

24

Nodakenin Suppresses Lipopolysaccharide-Induced Inflammatory Responses in Macrophage Cells by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 and Nuclear Factor- B Pathways and Protects Mice from Lethal Endotoxin Shock

Rim, H.-K., Cho, W., Sung, S. H., Lee, K.-T.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.48 MB

english, 2012

25

Soluble Glucan Is Internalized and Trafficked to the Golgi Apparatus in Macrophages via a Clathrin-Mediated, Lipid Raft-Regulated Mechanism

Ozment, T. R., Goldman, M. P., Kalbfleisch, J. H., Williams, D. L.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.00 MB

english, 2012

26

Vidofludimus Inhibits Colonic Interleukin-17 and Improves Hapten-Induced Colitis in Rats by a Unique Dual Mode of Action

Fitzpatrick, L. R., Small, J. S., Doblhofer, R., Ammendola, A.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 4.53 MB

english, 2012

27

Morphine Withdrawal Activates Hypothalamic-Pituitary-Adrenal Axis and Heat Shock Protein 27 in the Left Ventricle: The Role of Extracellular Signal-Regulated Kinase

Martinez-Laorden, E., Hurle, M. A., Milanes, M. V., Laorden, M. L., Almela, P.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 1019 KB

english, 2012

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