Volume 28; Issue 2

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Leukemia
Volume 28; Issue 2

Leukemia

Volume 28; Issue 2

1

Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications

Bjorklund, C C, Baladandayuthapani, V, Lin, H Y, Jones, R J, Kuiatse, I, Wang, H, Yang, J, Shah, J J, Thomas, S K, Wang, M, Weber, D M, Orlowski, R Z

Journal:

Year:

2014

Language:

english

File:

PDF, 1.00 MB

english, 2014

2

Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry

Puig, N, Sarasquete, M E, Balanzategui, A, Martínez, J, Paiva, B, García, H, Fumero, S, Jiménez, C, Alcoceba, M, Chillón, M C, Sebastián, E, Marín, L, Montalbán, M A, Mateos, M V, Oriol, A, Palomera,

Journal:

Year:

2014

Language:

english

File:

PDF, 896 KB

english, 2014

3

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

Walker, B A, Wardell, C P, Melchor, L, Brioli, A, Johnson, D C, Kaiser, M F, Mirabella, F, Lopez-Corral, L, Humphray, S, Murray, L, Ross, M, Bentley, D, Gutiérrez, N C, Garcia-Sanz, R, San Miguel, J,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

4

STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

Dorritie, K A, McCubrey, J A, Johnson, D E

Journal:

Year:

2014

Language:

english

File:

PDF, 702 KB

english, 2014

5

Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation

Grövdal, M, Karimi, M, Tobiasson, M, Reinius, L, Jansson, M, Ekwall, K, Ungerstedt, J, Kere, J, Greco, D, Hellström-Lindberg, E

Journal:

Year:

2014

Language:

english

File:

PDF, 844 KB

english, 2014

6

Hyperdiploidy with 49–65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome

Chilton, L, Hills, R K, Harrison, C J, Burnett, A K, Grimwade, D, Moorman, A V

Journal:

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

7

Cytogenetics and outcome of infants with acute lymphoblastic leukemia and absence of MLL rearrangements

De Lorenzo, P, Moorman, A V, Pieters, R, Dreyer, Z E, Heerema, N A, Carroll, A J, Hunger, S P, Harvey, R, Willman, C L, Devidas, M, Valsecchi, M-G, Harrison, C J

Journal:

Year:

2014

Language:

english

File:

PDF, 204 KB

english, 2014

8

Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

Patel, B, Kang, Y, Cui, K, Litt, M, Riberio, M S J, Deng, C, Salz, T, Casada, S, Fu, X, Qiu, Y, Zhao, K, Huang, S

Journal:

Year:

2014

Language:

english

File:

PDF, 3.43 MB

english, 2014

9

U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype

Tefferi, A, Finke, C M, Lasho, T L, Wassie, E A, Knudson, R, Ketterling, R P, Hanson, C A, Pardanani, A

Journal:

Year:

2014

Language:

english

File:

PDF, 149 KB

english, 2014

10

Use of the 46/1 haplotype to model JAK2V617F clonal architecture in PV patients: clonal evolution and impact of IFNα treatment

Hasan, S, Cassinat, B, Droin, N, Le Couedic, J P, Favale, F, Monte-Mor, B, Lacout, C, Fontenay, M, Dosquet, C, Chomienne, C, Solary, E, Villeval, J L, Casadevall, N, Kiladjian, J J, Vainchenker, W, Pl

Journal:

Year:

2014

Language:

english

File:

PDF, 355 KB

english, 2014

11

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

Dawson, M A, Gudgin, E J, Horton, S J, Giotopoulos, G, Meduri, E, Robson, S, Cannizzaro, E, Osaki, H, Wiese, M, Putwain, S, Fong, C Y, Grove, C, Craig, J, Dittmann, A, Lugo, D, Jeffrey, P, Drewes, G,

Journal:

Year:

2014

Language:

english

File:

PDF, 4.17 MB

english, 2014

12

The tumor suppressor axis p53/miR-34a regulates Axl expression in B-cell chronic lymphocytic leukemia: implications for therapy in p53-defective CLL patients

Boysen, J, Sinha, S, Price-Troska, T, Warner, S L, Bearss, D J, Viswanatha, D, Shanafelt, T D, Kay, N E, Ghosh, A K

Journal:

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

13

Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas

Sakamaki, I, Kwak, L W, Cha, S-c, Yi, Q, Lerman, B, Chen, J, Surapaneni, S, Bateman, S, Qin, H

Journal:

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

14

Induction of differential apoptotic pathways in multiple myeloma cells by class-selective histone deacetylase inhibitors

Hideshima, T, Mazitschek, R, Santo, L, Mimura, N, Gorgun, G, Richardson, P G, Raje, N, Anderson, K C

Journal:

Year:

2014

Language:

english

File:

PDF, 731 KB

english, 2014

15

Long-term response to lenalidomide in patients with newly diagnosed multiple myeloma

Kourelis, T V, Kumar, S K, Srivastava, G, Gertz, M A, Lacy, M Q, Buadi, F K, Kyle, R A, Dispenzieri, A

Journal:

Year:

2014

Language:

english

File:

PDF, 163 KB

english, 2014

16

Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation

Yasuda, T, Ueno, T, Fukumura, K, Yamato, A, Ando, M, Yamaguchi, H, Soda, M, Kawazu, M, Sai, E, Yamashita, Y, Murata, M, Kiyoi, H, Naoe, T, Mano, H

Journal:

Year:

2014

Language:

english

File:

PDF, 340 KB

english, 2014

17

JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma

Bouchekioua, A, Scourzic, L, de Wever, O, Zhang, Y, Cervera, P, Aline-Fardin, A, Mercher, T, Gaulard, P, Nyga, R, Jeziorowska, D, Douay, L, Vainchenker, W, Louache, F, Gespach, C, Solary, E, Coppo, P

Journal:

Year:

2014

Language:

english

File:

PDF, 2.35 MB

english, 2014

18

The NR4A orphan nuclear receptors do not confer prednisolone resistance in pediatric acute lymphoblastic leukemia

Ariës, I M, van den Dungen, E S R, Pieters, R, den Boer, M L

Journal:

Year:

2014

Language:

english

File:

PDF, 354 KB

english, 2014

19

Rapid detection of MYD88-L265P mutation by PCR-RFLP in B-cell lymphoproliferative disorders

Argentou, N, Vassilopoulos, G, Ioannou, M, Germenis, A E, Speletas, M

Journal:

Year:

2014

Language:

english

File:

PDF, 320 KB

english, 2014

20

Relationship between initial clinical presentation and the molecular cytogenetic classification of myeloma

Greenberg, A J, Rajkumar, S V, Therneau, T M, Singh, P P, Dispenzieri, A, Kumar, S K

Journal:

Year:

2014

Language:

english

File:

PDF, 360 KB

english, 2014

21

Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy

Koschmieder, S, Burmeister, T, Brüggemann, M, Berkemeier, A, Volpert, S, Wieacker, P, Silling, G, Gökbuget, N, Müller-Tidow, C, Berdel, W E, Stelljes, M

Journal:

Year:

2014

Language:

english

File:

PDF, 624 KB

english, 2014

22

Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia

Yuan, L L, Green, A S, Bertoli, S, Grimal, F, Mansat-De Mas, V, Dozier, C, Tamburini, J, Récher, C, Didier, C, Manenti, S

Journal:

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

23

The current status of minimal residual disease assessment in myeloma

Kumar, S K, Rajkumar, S V

Journal:

Year:

2014

Language:

english

File:

PDF, 100 KB

english, 2014

24

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia

Sportoletti, P, Baldoni, S, Del Papa, B, Aureli, P, Dorillo, E, Ruggeri, L, Plebani, S, Amico, V, Di Tommaso, A, Rosati, E, Marconi, P, Di Ianni, M, Falzetti, F

Journal:

Year:

2014

Language:

english

File:

PDF, 589 KB

english, 2014

25

IMWG consensus on risk stratification in multiple myeloma

Chng, W J, Dispenzieri, A, Chim, C-S, Fonseca, R, Goldschmidt, H, Lentzsch, S, Munshi, N, Palumbo, A, Miguel, J S, Sonneveld, P, Cavo, M, Usmani, S, Durie, B GM, Avet-Loiseau, H

Journal:

Year:

2014

Language:

english

File:

PDF, 355 KB

english, 2014

26

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients

Wong, K K, Gascoyne, D M, Brown, P J, Soilleux, E J, Snell, C, Chen, H, Lyne, L, Lawrie, C H, Gascoyne, R D, Pedersen, L M, Møller, M B, Pulford, K, Murphy, D, Green, T M, Banham, A H

Journal:

Year:

2014

Language:

english

File:

PDF, 1.78 MB

english, 2014

27

Association of response endpoints with survival outcomes in multiple myeloma

Lonial, S, Anderson, K C

Journal:

Year:

2014

Language:

english

File:

PDF, 467 KB

english, 2014

28

Combinatorial drug screening identifies synergistic co-targeting of Bruton’s tyrosine kinase and the proteasome in mantle cell lymphoma

Axelrod, M, Ou, Z, Brett, L K, Zhang, L, Lopez, E R, Tamayo, A T, Gordon, V, Ford, R J, Williams, M E, Pham, L V, Weber, M J, Wang, M L

Journal:

Year:

2014

Language:

english

File:

PDF, 645 KB

english, 2014

29

Rapid and long-lasting decrease of T-regulatory cells in patients with myelofibrosis treated with ruxolitinib

Massa, M, Rosti, V, Campanelli, R, Fois, G, Barosi, G

Journal:

Year:

2014

Language:

english

File:

PDF, 209 KB

english, 2014

30

Specificity and mechanism-of-action of the JAK2 tyrosine kinase inhibitors ruxolitinib and SAR302503 (TG101348)

Zhou, T, Georgeon, S, Moser, R, Moore, D J, Caflisch, A, Hantschel, O

Journal:

Year:

2014

Language:

english

File:

PDF, 819 KB

english, 2014

31

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

Haferlach, T, Nagata, Y, Grossmann, V, Okuno, Y, Bacher, U, Nagae, G, Schnittger, S, Sanada, M, Kon, A, Alpermann, T, Yoshida, K, Roller, A, Nadarajah, N, Shiraishi, Y, Shiozawa, Y, Chiba, K, Tanaka,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.08 MB

english, 2014

32

Bone marrow angiogenesis in myeloma and its precursor disease: a prospective clinical trial

Bhutani, M, Turkbey, B, Tan, E, Kemp, T J, Pinto, L A, Berg, A R, Korde, N, Minter, A R, Weiss, B M, Mena, E, Lindenberg, L, Aras, O, Purdue, M P, Hofmann, J N, Steinberg, S M, Calvo, K R, Choyke, P L

Journal:

Year:

2014

Language:

english

File:

PDF, 604 KB

english, 2014

33

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011

Olsson, L, Castor, A, Behrendtz, M, Biloglav, A, Forestier, E, Paulsson, K, Johansson, B

Journal:

Year:

2014

Language:

english

File:

PDF, 923 KB

english, 2014

34

Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies

Lemaire, M, D'Huyvetter, M, Lahoutte, T, Van Valckenborgh, E, Menu, E, De Bruyne, E, Kronenberger, P, Wernery, U, Muyldermans, S, Devoogdt, N, Vanderkerken, K

Journal:

Year:

2014

Language:

english

File:

PDF, 954 KB

english, 2014

35

Delineating MEIS1 cis-regulatory elements active in hematopoietic cells

Xiang, P, Wei, W, Lo, C, Rosten, P, Hou, J, Hoodless, P A, Bilenky, M, Bonifer, C, Cockerill, P N, Kirkpatrick, A, Gottgens, B, Hirst, M, Humphries, K R

Journal:

Year:

2014

Language:

english

File:

PDF, 549 KB

english, 2014

36

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts

Agnusdei, V, Minuzzo, S, Frasson, C, Grassi, A, Axelrod, F, Satyal, S, Gurney, A, Hoey, T, Seganfreddo, E, Basso, G, Valtorta, S, Moresco, R M, Amadori, A, Indraccolo, S

Journal:

Year:

2014

Language:

english

File:

PDF, 3.32 MB

english, 2014

37

Long-term results of a randomized phase 3 trial comparing idarubicin and daunorubicin in younger patients with acute myeloid leukaemia

Récher, C, Béné, M C, Lioure, B, Pigneux, A, Vey, N, Delaunay, J, Luquet, I, Hunault, M, Guyotat, D, Bouscary, D, Fegueux, N, Jourdan, E, Lissandre, S, Escoffre-Barbe, M, Bonmati, C, Randriamalala, E,

Journal:

Year:

2014

Language:

english

File:

PDF, 277 KB

english, 2014

38

Declining rates of treatment-related mortality in patients with newly diagnosed AML given ‘intense’ induction regimens: a report from SWOG and MD Anderson

Othus, M, Kantarjian, H, Petersdorf, S, Ravandi, F, Godwin, J, Cortes, J, Pierce, S, Erba, H, Faderl, S, Appelbaum, F R, Estey, E

Journal:

Year:

2014

Language:

english

File:

PDF, 183 KB

english, 2014

39

Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia

Bellanger, D, Jacquemin, V, Chopin, M, Pierron, G, Bernard, O A, Ghysdael, J, Stern, M-H

Journal:

Year:

2014

Language:

english

File:

PDF, 380 KB

english, 2014

40

No chromosome arm unturned: in memory of Roland Berger 1934–2012

Harrison, C J, Rowley, J D, Van den Berghe, H, Bernheim, A, Martineau, M, Gautier, M, Le Coniat-Busson, M, Romana, S, Dastugue, N, Hagemeijer, A, Jonveaux, P, Nguyen-Khac, F, Bernard, O A

Journal:

Year:

2014

Language:

english

File:

PDF, 462 KB

english, 2014

41

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients

Wong, K K, Gascoyne, D M, Brown, P J, Soilleux, E J, Snell, C, Chen, H, Lyne, L, Lawrie, C H, Gascoyne, R D, Pedersen, L M, Møller, M B, Pulford, K, Murphy, D, Green, T M, Banham, A H

Journal:

Year:

2014

Language:

english

File:

PDF, 104 KB

english, 2014

42

Specificity and mechanism-of-action of the JAK2 tyrosine kinase inhibitors ruxolitinib and SAR302503 (TG101348)

Zhou, T, Georgeon, S, Moser, R, Moore, D J, Caflisch, A, Hantschel, O

Journal:

Year:

2014

Language:

english

File:

PDF, 701 KB

english, 2014