Volume 5; Issue 6

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mAbs
Volume 5; Issue 6

mAbs

Volume 5; Issue 6

1

Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics

Golay, Josée, Semenzato, Gianpietro, Rambaldi, Alessandro, Foà, Robin, Gaidano, Gianluca, Gamba, Enrica, Pane, Fabrizio, Pinto, Antonello, Specchia, Giorgina, Zaja, Francesco, Regazzi, Mario

Journal:

Year:

2013

Language:

english

File:

PDF, 1.56 MB

english, 2013

2

High throughput detection of antibody self-interaction by bio-layer interferometry

Sun, Tingwan, Reid, Felicia, Liu, Yuqi, Cao, Yuan, Estep, Patricia, Nauman, Claire, Xu, Yingda

Journal:

Year:

2013

Language:

english

File:

PDF, 335 KB

english, 2013

3

Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys

Leabman, Maya K, Meng, Y Gloria, Kelley, Robert F, DeForge, Laura E, Cowan, Kyra J, Iyer, Suhasini

Journal:

Year:

2013

Language:

english

File:

PDF, 680 KB

english, 2013

4

A bispecific antibody against two different epitopes on hepatitis B surface antigen has potent hepatitis B virus neutralizing activity

Tan, Wenlong, Meng, Yanchun, Li, Hui, Chen, Yang, Han, Siqi, Zeng, Jing, Huang, Ang, Li, Bohua, Zhang, Yanyun, Guo, Yajun

Journal:

Year:

2013

Language:

english

File:

PDF, 2.82 MB

english, 2013

5

Analytical characterization of a monoclonal antibody therapeutic reveals a three-light chain species that is efficiently removed using hydrophobic interaction chromatography

Wollacott, Rachel B, Casaz, Paul L, Morin, Trevor J, Zhu, H Lily, Anderson, Roger S, Babcock, Gregory J, Que, John, Thomas Jr, William D, Ozturk, Sadettin S

Journal:

Year:

2013

Language:

english

File:

PDF, 1.42 MB

english, 2013

6

Effect of a tail piece cysteine deletion on biochemical and functional properties of an epidermal growth factor receptor-directed IgA2 m(1) antibody

Brunke, Christina, Lohse, Stefan, Derer, Stefanie, Peipp, Matthias, Boross, Peter, Kellner, Christian, Beyer, Thomas, Dechant, Michael, Royle, Louise, Liew, Li Phing, Leusen, Jeanette HW, Valerius, Th

Journal:

Year:

2013

Language:

english

File:

PDF, 2.33 MB

english, 2013

7

NFκB induces overexpression of bovine FcRn

Cervenak, Judit, Doleschall, Márton, Bender, Balázs, Mayer, Balázs, Schneider, Zita, Doleschall, Zoltán, Zhao, Yaofeng, Bősze, Zsuzsanna, Hammarström, Lennart, Oster, Wolfgang, Kacskovics, Imre

Journal:

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

8

In-depth qualitative and quantitative analysis of composite glycosylation profiles and other micro-heterogeneity on intact monoclonal antibodies by high-resolution native mass spectrometry using a modified Orbitrap

Rosati, Sara, van den Bremer, Ewald TJ, Schuurman, Janine, Parren, Paul WHI, Kamerling, Johannis P, Heck, Albert JR

Journal:

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

9

Inhibition of angiogenesis by a novel neutralizing antibody targeting human VEGFR-3

Chen, Hao, Ding, Xiuyun, Gao, Yuan, Jiang, Xiaohua, Liu, Xiaolan, Chen, Yong, Gao, Jianen, Zhou, Xiaping, Cai, Zhiming, Sun, Qihong

Journal:

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

10

In vitro assessment of the effects of vedolizumab binding on peripheral blood lymphocytes

Wyant, Tim, Yang, Lili, Fedyk, Eric

Journal:

Year:

2013

Language:

english

File:

PDF, 6.69 MB

english, 2013

11

Hydroxocobalamin association during cell culture results in pink therapeutic proteins

Prentice, Kenneth M, Gillespie, Ronald, Lewis, Nathan, Fujimori, Kiyoshi, McCoy, Rebecca, Bach, Julia, Connell-Crowley, Lisa, Eakin, Catherine M

Journal:

Year:

2013

Language:

english

File:

PDF, 1.09 MB

english, 2013

12

Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity

Shatz, Whitney, Chung, Shan, Li, Bing, Marshall, Brett, Tejada, Max, Phung, Wilson, Sandoval, Wendy, Kelley, Robert F, Scheer, Justin M

Journal:

Year:

2013

Language:

english

File:

PDF, 3.14 MB

english, 2013

13

The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics

Devanaboyina, Siva Charan, Lynch, Sandra M, Ober, Raimund J, Ram, Sripad, Kim, Dongyoung, Puig-Canto, Alberto, Breen, Shannon, Kasturirangan, Srinath, Fowler, Susan, Peng, Li, Zhong, Haihong, Jermutus

Journal:

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

14

Consequences of glycan truncation on Fc structural integrity

Buck, Patrick M, Kumar, Sandeep, Singh, Satish K

Journal:

Year:

2013

Language:

english

File:

PDF, 2.45 MB

english, 2013

15

Antibody Engineering and Therapeutics Conference

Almagro, Juan Carlos, Gilliland, Gary L, Scott, Jamie, Larrick, James W, Plückthun, Andreas, Veldman, Trudi, Adams, Gregory P, Parren, Paul WHI, Chester, Kerry A, Bradbury, Andrew, Reichert, Janice M,

Journal:

Year:

2013

Language:

english

File:

PDF, 194 KB

english, 2013

16

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery

Fennell, Brian J, McDonnell, Barry, Tam, Amy Sze Pui, Chang, Lijun, Steven, John, Broadbent, Ian D, Gao, Huilan, Kieras, Elizabeth, Alley, Jennifer, Luxenberg, Deborah, Edmonds, Jason, Fitz, Lori J, M

Journal:

Year:

2013

Language:

english

File:

PDF, 3.53 MB

english, 2013

17

Production of stable bispecific IgG1 by controlled Fab-arm exchange

Gramer, Michael J, van den Bremer, Ewald TJ, van Kampen, Muriel D, Kundu, Amitava, Kopfmann, Peter, Etter, Eric, Stinehelfer, David, Long, Justin, Lannom, Tom, Noordergraaf, Esther H, Gerritsen, Jolan

Journal:

Year:

2013

Language:

english

File:

PDF, 2.49 MB

english, 2013

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