Volume 6; Issue 5

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mAbs
Volume 6; Issue 5

mAbs

Volume 6; Issue 5

1

The human Müllerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer

Kersual, Nathalie, Garambois, Véronique, Chardès, Thierry, Pouget, Jean-Pierre, Salhi, Imed, Bascoul-Mollevi, Caroline, Bibeau, Frédéric, Busson, Muriel, Vié, Henri, Clémenceau, Béatrice, Behrens, Chr

Journal:

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

2

Rearranging the domain order of a diabody-based IgG-like bispecific antibody enhances its antitumor activity and improves its degradation resistance and pharmacokinetics

Asano, Ryutaro, Shimomura, Ippei, Konno, Shota, Ito, Akiko, Masakari, Yosuke, Orimo, Ryota, Taki, Shintaro, Arai, Kyoko, Ogata, Hiromi, Okada, Mai, Furumoto, Shozo, Onitsuka, Masayoshi, Omasa, Takeshi

Journal:

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

3

Physicochemical characterization of Remsima®

Jung, Soon Kwan, Lee, Kyoung Hoon, Jeon, Jae Won, Lee, Joon Won, Kwon, Byoung Oh, Kim, Yeon Jung, Bae, Jin Soo, Kim, Dong-Il, Lee, Soo Young, Chang, Shin Jae

Journal:

Year:

2014

Language:

english

File:

PDF, 1.40 MB

english, 2014

4

Bioanalytical strategy used in development of pharmacokinetic (PK) methods that support biosimilar programs

Colbert, Alex, Umble-Romero, Amber, Prokop, Samantha, Chow, Vincent Fung-Sing, Wong, Teresa, DeSimone, Danielle, Zhou, Lei, Pederson, Susan

Journal:

Year:

2014

Language:

english

File:

PDF, 663 KB

english, 2014

5

Blocking monoclonal antibodies of TIM proteins as orchestrators of anti-tumor immune response

Baghdadi, Muhammad, Takeuchi, Shintaro, Wada, Haruka, Seino, Ken-Ichiro

Journal:

Year:

2014

Language:

english

File:

PDF, 761 KB

english, 2014

6

Antibody engineering and therapeutics conference

Larrick, James W, Parren, Paul WHI, Huston, James S, Plückthun, Andreas, Bradbury, Andrew, Tomlinson, Ian M, Chester, Kerry A, Burton, Dennis R, Adams, Gregory P, Weiner, Louis M, Scott, Jamie K, Alfe

Journal:

Year:

2014

Language:

english

File:

PDF, 166 KB

english, 2014

7

Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge

Li, Bing, Tesar, Devin, Boswell, C Andrew, Cahaya, Hendry S, Wong, Anne, Zhang, Jianhuan, Meng, Y Gloria, Eigenbrot, Charles, Pantua, Homer, Diao, Jinyu, Kapadia, Sharookh B, Deng, Rong, Kelley, Rober

Journal:

Year:

2014

Language:

english

File:

PDF, 917 KB

english, 2014

8

Biosimilars entering the clinic without animal studies

van Aerts, Leon AGJM, De Smet, Karen, Reichmann, Gabriele, van der Laan, Jan Willem, Schneider, Christian K

Journal:

Year:

2014

Language:

english

File:

PDF, 372 KB

english, 2014

9

Effect of formulation on the stability and aerosol performance of a nebulized antibody

Respaud, Renaud, Marchand, Denis, Parent, Christelle, Pelat, Thibaut, Thullier, Philippe, Tournamille, Jean-François, Viaud-Massuard, Marie-Claude, Diot, Patrice, Si-Tahar, Mustapha, Vecellio, Laurent

Journal:

Year:

2014

Language:

english

File:

PDF, 436 KB

english, 2014

10

A general approach to antibody thermostabilization

McConnell, Audrey D, Zhang, Xue, Macomber, John L, Chau, Betty, Sheffer, Joseph C, Rahmanian, Sorena, Hare, Eric, Spasojevic, Vladimir, Horlick, Robert A, King, David J, Bowers, Peter M

Journal:

Year:

2014

Language:

english

File:

PDF, 730 KB

english, 2014

11

In vitro and in vivo modifications of recombinant and human IgG antibodies

Liu, Hongcheng, Ponniah, Gomathinayagam, Zhang, Hui-Min, Nowak, Christine, Neill, Alyssa, Gonzalez-Lopez, Nidia, Patel, Rekha, Cheng, Guilong, Kita, Adriana Z, Andrien, Bruce

Journal:

Year:

2014

Language:

english

File:

PDF, 190 KB

english, 2014

12

A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies

Stracke, Jan, Emrich, Thomas, Rueger, Petra, Schlothauer, Tilman, Kling, Lothar, Knaupp, Alexander, Hertenberger, Hubert, Wolfert, Andreas, Spick, Christian, Lau, Wilma, Drabner, Georg, Reiff, Ulrike,

Journal:

Year:

2014

Language:

english

File:

PDF, 731 KB

english, 2014

13

Targeting arterial wall sulfated glycosaminoglycans in rabbit atherosclerosis with a mouse/human chimeric antibody

Soto, Yosdel, Mesa, Niurka, Alfonso, Yumisley, Pérez, Arlenis, Batlle, Fernando, Griñán, Tania, Pino, Adonis, Viera, Justo, Frómeta, Milagros, Brito, Victor, Olivera, Armando, Zayas, Francisco, Vázque

Journal:

Year:

2014

Language:

english

File:

PDF, 823 KB

english, 2014

14

Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase

Thueng-in, Kanyarat, Thanongsaksrikul, Jeeraphong, Jittavisutthikul, Surasak, Seesuay, Watee, Chulanetra, Monrat, Sakolvaree, Yuwaporn, Srimanote, Potjanee, Chaicumpa, Wanpen

Journal:

Year:

2014

Language:

english

File:

PDF, 1001 KB

english, 2014

15

A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo

Brezski, Randall J, Kinder, Michelle, Grugan, Katharine D, Soring, Keri L, Carton, Jill, Greenplate, Allison R, Petley, Theodore, Capaldi, Dorie, Brosnan, Kerry, Emmell, Eva, Watson, Sharon, Jordan, R

Journal:

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

16

Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody

Hristodorov, Dmitrij, Mladenov, Radoslav, Brehm, Hannes, Fischer, Rainer, Barth, Stefan, Thepen, Theo

Journal:

Year:

2014

Language:

english

File:

PDF, 557 KB

english, 2014

17

Effect of antigen-dependent clearance on pharmacokinetics of anti-heparin-binding EGF-like growth factor (HB-EGF) monoclonal antibody

Kasai, Noriyuki, Yoshikawa, Yukitaka, Enokizono, Junichi

Journal:

Year:

2014

Language:

english

File:

PDF, 685 KB

english, 2014

18

Site-specific antibody-drug conjugation through an engineered glycotransferase and a chemically reactive sugar

Zhu, Zhongyu, Ramakrishnan, Boopathy, Li, Jinyu, Wang, Yanping, Feng, Yang, Prabakaran, Ponraj, Colantonio, Simona, Dyba, Marzena A, Qasba, Pradman K, Dimitrov, Dimiter S

Journal:

Year:

2014

Language:

english

File:

PDF, 843 KB

english, 2014

19

Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases

Ying, Tianlei, Feng, Yang, Wang, Yanping, Chen, Weizao, Dimitrov, Dimiter S.

Journal:

Year:

2014

Language:

english

File:

PDF, 716 KB

english, 2014

20

Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist

Thaventhiran, Thilipan, Alhumeed, Naif, Yeang, Han XA, Sethu, Swaminathan, Downey, Jocelyn S, Alghanem, Ahmad F, Olayanju, Adedamola, Smith, Emma L, Cross, Michael J, Webb, Steven D, Williams, Dominic

Journal:

Year:

2014

Language:

english

File:

PDF, 768 KB

english, 2014

21

Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer

Meyer, Saskia, Leusen, Jeanette HW, Boross, Peter

Journal:

Year:

2014

Language:

english

File:

PDF, 444 KB

english, 2014

22

Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies

Winiarska, Magdalena, Bojarczuk, Kamil, Pyrzynska, Beata, Bil, Jacek, Siernicka, Marta, Dwojak, Michal, Bobrowicz, Malgorzata, Miazek, Nina, Zapala, Piotr, Zagozdzon, Agnieszka, Krol, Magdalena, Syta,

Journal:

Year:

2014

Language:

english

File:

PDF, 1024 KB

english, 2014

23

The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells

Ram, Sripad, Kim, Dongyoung, Ober, Raimund J, Ward, E Sally

Journal:

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

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