Volume 7; Issue 1

Main
mAbs
Volume 7; Issue 1

mAbs

Volume 7; Issue 1

1

Antibodies to watch in 2015

Reichert, Janice M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

2

The therapeutic monoclonal antibody market

Ecker, Dawn M, Jones, Susan Dana, Levine, Howard L

Journal:

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

3

Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life

Majumdar, Ranajoy, Esfandiary, Reza, Bishop, Steven M, Samra, Hardeep S, Middaugh, C Russell, Volkin, David B, Weis, David D

Journal:

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

4

Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells

Chang, Chien-Hsing, Wang, Yang, Gupta, Pankaj, Goldenberg, David M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

5

Affinity maturation of a novel antagonistic human monoclonal antibody with a long V H CDR3 targeting the Class A GPCR formyl-peptide receptor 1

Douthwaite, Julie A, Sridharan, Sudharsan, Huntington, Catherine, Hammersley, Jayne, Marwood, Rose, Hakulinen, Jonna K, Ek, Margareta, Sjögren, Tove, Rider, David, Privezentzev, Cyril, Seaman, Jonatha

Journal:

Year:

2015

Language:

english

File:

PDF, 891 KB

english, 2015

6

Nanocell targeting using engineered bispecific antibodies

Taylor, Karin, Howard, Christopher B, Jones, Martina L, Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P, Mahler, Stephen M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

7

Production of bispecific antibodies in “knobs-into-holes” using a cell-free expression system

Xu, Yiren, Lee, John, Tran, Cuong, Heibeck, Tyler H, Wang, Willie D, Yang, Junhao, Stafford, Ryan L, Steiner, Alexander R, Sato, Aaron K, Hallam, Trevor J, Yin, Gang

Journal:

Year:

2015

Language:

english

File:

PDF, 805 KB

english, 2015

8

Functional inhibition of β-catenin-mediated Wnt signaling by intracellular VHH antibodies

Newnham, Laura E, Wright, Michael J, Holdsworth, Gill, Kostarelos, Kostas, Robinson, Martyn K, Rabbitts, Terence H, Lawson, Alastair D

Journal:

Year:

2015

Language:

english

File:

PDF, 850 KB

english, 2015

9

Structural insights and biomedical potential of IgNAR scaffolds from sharks

Zielonka, Stefan, Empting, Martin, Grzeschik, Julius, Könning, Doreen, Barelle, Caroline J, Kolmar, Harald

Journal:

Year:

2015

Language:

english

File:

PDF, 861 KB

english, 2015

10

Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope “tags”

Percival-Alwyn, Jennifer L, England, Elizabeth, Kemp, Benjamin, Rapley, Laura, Davis, Nicola HE, McCarthy, Grant R, Majithiya, Jayesh B, Corkill, Dominic J, Welsted, Sarah, Minton, Kevin, Cohen, E Suz

Journal:

Year:

2015

Language:

english

File:

PDF, 332 KB

english, 2015

11

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 1: Separation-based methods

Reusch, Dietmar, Haberger, Markus, Maier, Bernd, Maier, Maria, Kloseck, Ronny, Zimmermann, Boris, Hook, Michaela, Szabo, Zoltan, Tep, Samnang, Wegstein, Jo, Alt, Nadja, Bulau, Patrick, Wuhrer, Manfred

Journal:

Year:

2015

Language:

english

File:

PDF, 911 KB

english, 2015

12

Early developability screen of therapeutic antibody candidates using Taylor dispersion analysis and UV area imaging detection

Lavoisier, Alexandra, Schlaeppi, Jean-Marc

Journal:

Year:

2015

Language:

english

File:

PDF, 449 KB

english, 2015

13

A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast display

Schröter, Christian, Günther, Ralf, Rhiel, Laura, Becker, Stefan, Toleikis, Lars, Doerner, Achim, Becker, Janine, Schönemann, Andreas, Nasu, Daichi, Neuteboom, Berend, Kolmar, Harald, Hock, Björn

Journal:

Year:

2015

Language:

english

File:

PDF, 1.15 MB

english, 2015

14

Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody

Rouha, Harald, Badarau, Adriana, Visram, Zehra C, Battles, Michael B, Prinz, Bianka, Magyarics, Zoltán, Nagy, Gábor, Mirkina, Irina, Stulik, Lukas, Zerbs, Manuel, Jägerhofer, Michaela, Maierhofer, Bar

Journal:

Year:

2015

Language:

english

File:

PDF, 1009 KB

english, 2015

15

High contrast tumor imaging with radio-labeled antibody Fab fragments tailored for optimized pharmacokinetics via PASylation

Mendler, Claudia T, Friedrich, Lars, Laitinen, Iina, Schlapschy, Martin, Schwaiger, Markus, Wester, Hans-Jürgen, Skerra, Arne

Journal:

Year:

2015

Language:

english

File:

PDF, 637 KB

english, 2015

16

Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle

Zhang, Kathy, Geddie, Melissa L, Kohli, Neeraj, Kornaga, Tad, Kirpotin, Dmitri B, Jiao, Yang, Rennard, Rachel, Drummond, Daryl C, Nielsen, Ulrik B, Xu, Lihui, Lugovskoy, Alexey A

Journal:

Year:

2015

Language:

english

File:

PDF, 714 KB

english, 2015

17

Large scale production of phage antibody libraries using a bioreactor

Ferrara, Fortunato, Kim, Chang-Yub, Naranjo, Leslie A, Bradbury, Andrew RM

Journal:

Year:

2015

Language:

english

File:

PDF, 516 KB

english, 2015

18

Surrogate target cells expressing surface anti-idiotype antibody for the clinical evaluation of an internalizing CD22-specific antibody

Leung, Shui-on, Gao, Kai, Wang, Guang Yu, Cheung, Benny Ka-wa, Lee, Kwan-yeung, Zhao, Qi, Cheung, Wing-Tai, Wang, Jun Zhi

Journal:

Year:

2015

Language:

english

File:

PDF, 979 KB

english, 2015

19

Rational design of viscosity reducing mutants of a monoclonal antibody: Hydrophobic versus electrostatic inter-molecular interactions

Nichols, Pilarin, Li, Li, Kumar, Sandeep, Buck, Patrick M, Singh, Satish K, Goswami, Sumit, Balthazor, Bryan, Conley, Tami R, Sek, David, Allen, Martin J

Journal:

Year:

2015

Language:

english

File:

PDF, 770 KB

english, 2015

20

Effect of kinase inhibitors on the therapeutic properties of monoclonal antibodies

Duong, Minh Ngoc, Matera, Eva-Laure, Mathé, Doriane, Evesque, Anne, Valsesia-Wittmann, Sandrine, Clémenceau, Béatrice, Dumontet, Charles

Journal:

Year:

2015

Language:

english

File:

PDF, 614 KB

english, 2015

21

Evaluation of cetuximab as a candidate for targeted α-particle radiation therapy of HER1-positive disseminated intraperitoneal disease

Milenic, Diane E, Baidoo, Kwamena E, Kim, Young-Seung, Brechbiel, Martin W

Journal:

Year:

2015

Language:

english

File:

PDF, 765 KB

english, 2015

22

Recombinant renewable polyclonal antibodies

Ferrara, Fortunato, D’Angelo, Sara, Gaiotto, Tiziano, Naranjo, Leslie, Tian, Hongzhao, Gräslund, Susanne, Dobrovetsky, Elena, Hraber, Peter, Lund-Johansen, Fridtjof, Saragozza, Silvia, Sblattero, Dani

Journal:

Year:

2015

Language:

english

File:

PDF, 1016 KB

english, 2015

23

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein

Curtin, François, Perron, Hervé, Kromminga, Arno, Porchet, Hervé, Lang, Alois B

Journal:

Year:

2015

Language:

english

File:

PDF, 963 KB

english, 2015

24

Characterization of monoclonal antibody's binding kinetics using oblique-incidence reflectivity difference approach

Liu, Shuang, Zhang, Hongyan, Dai, Jun, Hu, Shaohu, Pino, Ignacio, Eichinger, Daniel J, Lyu, Huibin, Zhu, Heng

Journal:

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

25

Therapeutic monoclonal antibodies and the need for targeted pharmacovigilance in India

Kalaivani, M, Singh, Abhishank, Kalaiselvan, V

Journal:

Year:

2015

Language:

english

File:

PDF, 378 KB

english, 2015

26

Non–antigen-contacting region of an asymmetric bispecific antibody to factors IXa/X significantly affects factor VIII-mimetic activity

Sampei, Zenjiro, Igawa, Tomoyuki, Soeda, Tetsuhiro, Funaki, Miho, Yoshihashi, Kazutaka, Kitazawa, Takehisa, Muto, Atsushi, Kojima, Tetsuo, Nakamura, Satoshi, Hattori, Kunihiro

Journal:

Year:

2015

Language:

english

File:

PDF, 1005 KB

english, 2015

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