Volume 2; Issue 10

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MedChemComm
Volume 2; Issue 10

MedChemComm

Volume 2; Issue 10

1

Are pyridazines privileged structures?

Wermuth, Camille G.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

2

Synthesis and biological evaluation of a new class of anti-brucella compounds targeting histidinol dehydrogenase: α-O-arylketones and α-S-arylketones derived from histidine

Turtaut, François, Ouahrani-Bettache, Safia, Montero, Jean-Louis, Köhler, Stephan, Winum, Jean-Yves

Journal:

Year:

2011

Language:

english

File:

PDF, 144 KB

english, 2011

3

Design, synthesis and antiproliferative activity of urocanic-chalcone hybrid derivatives

Ciupa, Alexander, Griffiths, Natalie J., Light, Stephanie K., Wood, Pauline J., Caggiano, Lorenzo

Journal:

Year:

2011

Language:

english

File:

PDF, 320 KB

english, 2011

4

A new route to indoles via in situ desilylation–Sonogashira strategy: identification of novel small molecules as potential anti-tuberculosis agents

Nakhi, Ali, Prasad, Bagineni, Reddy, Uppender, Rao, Raja Mohan, Sandra, Sandhya, Kapavarapu, Ravikumar, Rambabu, D., Rama Krishna, G., Reddy, C. Malla, Ravada, Kishore, Misra, Parimal, Iqbal, Javed, P

Journal:

Year:

2011

Language:

english

File:

PDF, 277 KB

english, 2011

5

Aminomethyl substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists

Shook, Brian C., Charavarty, Devraj, Barbay, J. Kent, Wang, Aihua, Leonard, Kristi, Alford, Vernon, Powell, Mark, Beauchamp, Derek A., Rassnick, Stefanie, Scannevin, Robert, Carroll, Karen, Wallace, N

Journal:

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

6

Discovery of CP-866,087, a mu opioid receptor antagonist for the treatment of alcohol abuse and dependence

McHardy, Stanton F., Heck, Steven D., Guediche, Sara, Kalman, Monica, Allen, Martin P., Tu, Meihua, Bryce, Dianne K., Schmidt, Anne W., Vanase-Frawley, Michelle, Callegari, Ernesto, Doran, Shawn, Grah

Journal:

Year:

2011

Language:

english

File:

PDF, 151 KB

english, 2011

7

2-[(1,3-Dihydro-2H-isoindol-2-yl)methyl]melatonin – a novel MT2-selective melatonin receptor antagonist

Heckman, David, Attia, Mohamed I., Behnam, Mira A. M., Mohsen, Amal M. Y., Markl, Christian, Julius, Justin, Sethi, Shalini, Witt-Enderby, Paula A., Zlotos, Darius P.

Journal:

Year:

2011

Language:

english

File:

PDF, 152 KB

english, 2011

8

Identification of 3-aminothieno[2,3-b]pyridine-2-carboxamides and 4-aminobenzothieno[3,2-d]pyrimidines as LIMK1 inhibitors

Sleebs, Brad E., Levit, Alla, Street, Ian P., Falk, Hendrik, Hammonds, Tim, Wong, Ai Ching, Charles, Mark D., Olson, Michael F., Baell, Jonathan B.

Journal:

Year:

2011

Language:

english

File:

PDF, 156 KB

english, 2011

9

Inside front cover

Journal:

Year:

2011

Language:

english

File:

PDF, 675 KB

english, 2011

10

A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

Peukert, Stefan, Nunez, Jill, He, Feng, Dai, Miao, Yusuff, Naeem, DiPesa, Alan, Miller-Moslin, Karen, Karki, Rajesh, Lagu, Bharat, Harwell, Chris, Zhang, Yalin, Bauer, Daniel, Kelleher, Joseph F., Ega

Journal:

Year:

2011

Language:

english

File:

PDF, 116 KB

english, 2011

11

A pseudorotaxane umbrella thread with chloride transmembrane transport properties

Chhun, Christine, Schmitzer, Andreea R.

Journal:

Year:

2011

Language:

english

File:

PDF, 335 KB

english, 2011

12

Towards kit-like 18F-labeling of marimastat, a noncovalent inhibitor drug for in vivo PET imaging cancer associated matrix metalloproteases

Li, Ying, Ting, Richard, Harwig, Curtis W., auf dem Keller, Ulrich, Bellac, Caroline L., Lange, Philipp F., Inkster, James A. H., Schaffer, Paul, Adam, Michael J., Ruth, Thomas J., Overall, Christophe

Journal:

Year:

2011

Language:

english

File:

PDF, 826 KB

english, 2011

13

The synthesis and evaluation of dihydroquinazolin-4-ones and quinazolin-4-ones as thyroid stimulating hormone receptor agonists

Englund, Erika E., Neumann, Susanne, Eliseeva, Elena, McCoy, Joshua G., Titus, Steven, Zheng, Wei, Southall, Noel, Shinn, Paul, Leister, William, Thomas, Craig J., Inglese, James, Austin, Christopher

Journal:

Year:

2011

Language:

english

File:

PDF, 132 KB

english, 2011

14

Front cover

Journal:

Year:

2011

Language:

english

File:

PDF, 596 KB

english, 2011

15

Design, synthesis and biological evaluation of γ-lactam hydroxamate based TACE inhibitors

Argade, Anil, Bahekar, Rajesh, Desai, Jigar, Thombare, Pravin, Shah, Kiran, Gite, Sanjay, Sunder, Rajesh, Ranvir, Ramchandra, Bandyopadhyay, Debdutta, Chakrabarti, Ganes, Joharapurkar, Amit, Mahapatra

Journal:

Year:

2011

Language:

english

File:

PDF, 183 KB

english, 2011

16

Back cover

Journal:

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

17

Contents list

Journal:

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

18

Development of substituted 7-phenyl-4-aminobenzothieno[3,2-d] pyrimidines as potent LIMK1 inhibitors

Sleebs, Brad E., Ganame, Danny, Levit, Alla, Street, Ian P., Gregg, Alison, Falk, Hendrik, Baell, Jonathan B.

Journal:

Year:

2011

Language:

english

File:

PDF, 114 KB

english, 2011