Volume 4; Issue 6

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MedChemComm
Volume 4; Issue 6

MedChemComm

Volume 4; Issue 6

1

Development of new N-arylbenzamides as STAT3 dimerization inhibitors

Urlam, Murali K., Pireddu, Roberta, Ge, Yiyu, Zhang, Xiaolei, Sun, Ying, Lawrence, Harshani R., Guida, Wayne C., Sebti, Saïd M., Lawrence, Nicholas J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

2

Discovery of novel inhibitors for human farnesyltransferase (hFTase) via structure-based virtual screening

Yu, Xiaojuan, Zhao, Xue, Zhu, Lili, Zou, Chuanxin, Liu, Xiaofeng, Zhao, Zhenjiang, Huang, Jin, Li, Honglin

Journal:

Year:

2013

Language:

english

File:

PDF, 907 KB

english, 2013

3

A quantum chemical view of enthalpy–entropy compensation

Journal:

Year:

2013

Language:

english

File:

PDF, 497 KB

english, 2013

4

TrxR inhibition and antiproliferative activities of structurally diverse gold N-heterocyclic carbene complexes

Rubbiani, Riccardo, Schuh, Esther, Meyer, Andreas, Lemke, Jessika, Wimberg, Jan, Metzler-Nolte, Nils, Meyer, Franc, Mohr, Fabian, Ott, Ingo

Journal:

Year:

2013

Language:

english

File:

PDF, 607 KB

english, 2013

5

Chiral 1,1-diaryl compounds as important pharmacophores

Ameen, Dana, Snape, Timothy J.

Journal:

Year:

2013

Language:

english

File:

PDF, 514 KB

english, 2013

6

Design and synthesis of β-amino alcohol based β-lactam–isatin chimeras and preliminary analysis of in vitro activity against the protozoal pathogen Trichomonas vaginalis

Nisha,, Mehra, Vishu, Hopper, Melissa, Patel, Neal, Hall, Dominique, Wrischnik, Lisa A., Land, Kirkwood M., Kumar, Vipan

Journal:

Year:

2013

Language:

english

File:

PDF, 281 KB

english, 2013

7

Synthesis and antiproliferative activity of some 3-(pyrid-2-yl)-pyrazolines

Ciupa, Alexander, De Bank, Paul A., Mahon, Mary F., Wood, Pauline J., Caggiano, Lorenzo

Journal:

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

8

Meridianin G and its analogs as antimalarial agents

Bharate, Sandip B., Yadav, Rammohan R., Khan, Shabana I., Tekwani, Babu L., Jacob, Melissa R., Khan, Ikhlas A., Vishwakarma, Ram A.

Journal:

Year:

2013

Language:

english

File:

PDF, 253 KB

english, 2013

9

Design and discovery of 4-anilinoquinazoline ureas as multikinase inhibitors targeting BRAF, VEGFR-2 and EGFR

Zhang, Qingwen, Diao, Yuanyuan, Wang, Fei, Fu, Ying, Tang, Fei, You, Qidong, Zhou, Houyuan

Journal:

Year:

2013

Language:

english

File:

PDF, 546 KB

english, 2013

10

Design, synthesis and biological evaluation of novel indano- and thiaindano-pyrazoles with potential interest for Alzheimer's disease

Genest, David, Rochais, Christophe, Lecoutey, Cédric, Oliveira Santos, Jana Sopkova-de, Ballandonne, Céline, Butt-Gueulle, Sabrina, Legay, Remi, Since, Marc, Dallemagne, Patrick

Journal:

Year:

2013

Language:

english

File:

PDF, 381 KB

english, 2013

11

RCAI-133, an N-methylated analogue of KRN7000, activates mouse natural killer T cells to produce Th2-biased cytokines

Tashiro, Takuya, Shigeura, Tomokuni, Shiozaki, Masao, Watarai, Hiroshi, Taniguchi, Masaru, Mori, Kenji

Journal:

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

12

Synthesis of coumarin–chalcone hybrids and evaluation of their antioxidant and trypanocidal properties

Vazquez-Rodriguez, Saleta, Figueroa-Guíñez, Roberto, Matos, Maria João, Santana, Lourdes, Uriarte, Eugenio, Lapier, Michel, Maya, Juan Diego, Olea-Azar, Claudio

Journal:

Year:

2013

Language:

english

File:

PDF, 393 KB

english, 2013

13

Indole–triazole conjugates are selective inhibitors and inducers of bacterial biofilms

Minvielle, Marine J., Bunders, Cynthia A., Melander, Christian

Journal:

Year:

2013

Language:

english

File:

PDF, 228 KB

english, 2013

14

Targeted cancer cell inhibition using multifunctional dendrimer-entrapped gold nanoparticles

Zheng, Linfeng, Zhu, Jingyi, Shen, Mingwu, Chen, Xisui, Baker, James R., Wang, Su He, Zhang, Guixiang, Shi, Xiangyang

Journal:

Year:

2013

Language:

english

File:

PDF, 750 KB

english, 2013

15

Antifolates as effective antimicrobial agents: new generations of trimethoprim analogs

Zhou, Wangda, Scocchera, Eric W., Wright, Dennis L., Anderson, Amy C.

Journal:

Year:

2013

Language:

english

File:

PDF, 877 KB

english, 2013

16

Synthesis and cytotoxicity evaluation of regioisomeric substituted N-phenyl-3′-(chrom-4-one-3-yl)-isoxazolidines: induction of apoptosis through a mitochondrial-dependent pathway

Singh, Gagandeep, Kaur, Amritpal, Sharma, Vishal, Suri, Nitasha, Sharma, Parduman R., Saxena, Ajit. K., Ishar, Mohan Paul S.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

17

Identification of novel farnesoid X receptor modulators using a combined ligand- and structure-based virtual screening

Achenbach, Janosch, Gabler, Matthias, Steri, Ramona, Schubert-Zsilavecz, Manfred, Proschak, Ewgenij

Journal:

Year:

2013

Language:

english

File:

PDF, 24.77 MB

english, 2013

18

The use of 111Ag as a tool for studying biological distribution of silver-based antimicrobials

Aweda, Tolulope A., Ikotun, Oluwatayo, Mastren, Tara, Cannon, Carolyn L., Wright, Brian, Youngs, Wiley J., Cutler, Cathy, Guthrie, James, Lapi, Suzanne E.

Journal:

Year:

2013

Language:

english

File:

PDF, 229 KB

english, 2013

19

Synthesis, docking and preliminary in vivo evaluation of serotonin dithiocarbamate as novel SPECT neuroimaging agent

Chaturvedi, Shubhra, Kaul, Ankur, Yadav, Neelam, Singh, B., Mishra, Anil K.

Journal:

Year:

2013

Language:

english

File:

PDF, 859 KB

english, 2013

20

Identification of a potent salicylic acid-based inhibitor of tyrosine phosphatase PTP1B

Haftchenary, Sina, Ball, Daniel P., Aubry, Isabelle, Landry, Melissa, Shahani, Vijay M., Fletcher, Steven, Page, Brent D. G., Jouk, Andriana O., Tremblay, Michel L., Gunning, Patrick T.

Journal:

Year:

2013

Language:

english

File:

PDF, 455 KB

english, 2013

21

Contents list

Journal:

Year:

2013

Language:

english

File:

PDF, 1.74 MB

english, 2013

22

Introduction of methionine mimics on 3-arylthiophene: influence on protein farnesyltransferase inhibition and on antiparasitic activity

Bosc, Damien, Mouray, Elisabeth, Grellier, Philippe, Cojean, Sandrine, Loiseau, Philippe M., Dubois, Joëlle

Journal:

Year:

2013

Language:

english

File:

PDF, 289 KB

english, 2013

23

Back cover

Journal:

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

24

Front cover

Journal:

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

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