Volume 5; Issue 3

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MedChemComm
Volume 5; Issue 3

MedChemComm

Volume 5; Issue 3

1

10.1039/C3MD00315A

Journal:

Language:

english

File:

PDF, 684 KB

english

2

10.1039/C3MD00277B

Journal:

Language:

english

File:

PDF, 939 KB

english

3

10.1039/c3md00288h

Journal:

Language:

english

File:

PDF, 913 KB

english

4

Affinity-based target identification for bioactive small molecules

Kawatani, Makoto, Osada, Hiroyuki

Journal:

Year:

2014

Language:

english

File:

PDF, 528 KB

english, 2014

5

10.1039/C3MD00283G

Journal:

Language:

english

File:

PDF, 1.12 MB

english

6

The structure based design of dual HDAC/BET inhibitors as novel epigenetic probes

Atkinson, Stephen J., Soden, Peter E., Angell, Davina C., Bantscheff, Marcus, Chung, Chun-wa, Giblin, Kathryn A., Smithers, Nicholas, Furze, Rebecca C., Gordon, Laurie, Drewes, Gerard, Rioja, Inmacula

Journal:

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

7

10.1039/C3MD00333G

Journal:

Language:

english

File:

PDF, 1008 KB

english

8

Necrosulfonamide inhibits necroptosis by selectively targeting the mixed lineage kinase domain-like protein

Liao, Daohong, Sun, Liming, Liu, Weilong, He, Sudan, Wang, Xiaodong, Lei, Xiaoguang

Journal:

Year:

2014

Language:

english

File:

PDF, 500 KB

english, 2014

9

Identification of an inhibitor of the ubiquitin–proteasome system that induces accumulation of polyubiquitinated proteins in the absence of blocking of proteasome function

Haglund, Caroline, Mohanty, Chitralekha, Fryknäs, Mårten, D'Arcy, Padraig, Larsson, Rolf, Linder, Stig, Rickardson, Linda

Journal:

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

10

The chemistry and biology of the α-ketoglutarate-dependent histone Nε-methyl-lysine demethylases

Zheng, Weiping, Huang, Yajun

Journal:

Year:

2014

Language:

english

File:

PDF, 974 KB

english, 2014

11

Comparative mode-of-action analysis following manual and automated phenotype detection in Xenopus laevis

Drakakis, Georgios, Hendry, Adam E., Hanson, Kimberley, Brewerton, Suzanne C., Bodkin, Michael J., Evans, David A., Wheeler, Grant N., Bender, Andreas

Journal:

Year:

2014

Language:

english

File:

PDF, 852 KB

english, 2014

12

FP tethering: a screening technique to rapidly identify compounds that disrupt protein–protein interactions

Lodge, Jean M., Justin Rettenmaier, T., Wells, James A., Pomerantz, William C., Mapp, Anna K.

Journal:

Year:

2014

Language:

english

File:

PDF, 766 KB

english, 2014

13

Inside front cover

Journal:

Year:

2014

File:

PDF, 329 KB

2014

14

Contents list

Journal:

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

15

Development of CBAP-BPyne, a probe for γ-secretase and presenilinase

Gertsik, Natalya, Ballard, T. Eric, am Ende, Christopher W., Johnson, Douglas S., Li, Yue-Ming

Journal:

Year:

2014

Language:

english

File:

PDF, 844 KB

english, 2014

16

10.1039/c3md00289f

Journal:

Language:

english

File:

PDF, 741 KB

english

17

Back cover

Journal:

Year:

2014

Language:

english

File:

PDF, 432 KB

english, 2014

18

Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase I

Zhou, Yiqing, Guo, Tianlin, Li, Xitao, Dong, Yi, Galatsis, Paul, Johnson, Douglas S., Pan, Zhengying

Journal:

Year:

2014

Language:

english

File:

PDF, 454 KB

english, 2014

19

Validation of host factors of HIV integration as novel drug targets for anti-HIV therapy

Debyser, Zeger, Desimmie, Belete A., Taltynov, Oliver, Demeulemeester, Jonas, Christ, Frauke

Journal:

Year:

2014

Language:

english

File:

PDF, 413 KB

english, 2014

20

When tight is too tight: Dasatinib and its lower affinity analogue for profiling kinase inhibitors in a three-hybrid split-luciferase system

Ogunleye, Luca O., Jester, Benjamin W., Riemen, Alexander J., Badran, Ahmed H., Wang, Ping, Ghosh, Indraneel

Journal:

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

21

Front cover

Journal:

Year:

2014

File:

PDF, 349 KB

2014

22

Discovery of BET bromodomain inhibitors and their role in target validation

Müller, S., Knapp, S.

Journal:

Year:

2014

Language:

english

File:

PDF, 791 KB

english, 2014

23

Chemical biology for target identification and validation

Journal:

Year:

2014

Language:

english

File:

PDF, 165 KB

english, 2014