Volume 8; Issue 3

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MedChemComm
Volume 8; Issue 3

MedChemComm

Volume 8; Issue 3

1

Structure–activity relationships for the synthesis of selective cyclooxygenase 2 inhibitors: an overview (2009–2016)

Carullo, G., Galligano, F., Aiello, F.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.96 MB

english, 2017

2

Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones

Goud, Gudikadi Linga, Ramesh, Seela, Ashok, Dongamanti, Reddy, Vummenthala Prabhakar, Yogeeswari, Perumal, Sriram, Dharmarajan, Saikrishna, Balabadra, Manga, Vijjulatha

Journal:

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

3

Recent advances in the medicinal chemistry of group II and group III mGlu receptors

Jin, Chaobin, Ma, Shutao

Journal:

Year:

2017

Language:

english

File:

PDF, 944 KB

english, 2017

4

A scaffold merging approach to Hsp90 C-terminal inhibition: synthesis and evaluation of a chimeric library

Davis, Rachel E., Zhang, Zheng, Blagg, Brian S. J.

Journal:

Year:

2017

Language:

english

File:

PDF, 898 KB

english, 2017

5

Discovery of potent human lactate dehydrogenase A (LDHA) inhibitors with antiproliferative activity against lung cancer cells: virtual screening and biological evaluation

Li, Xiao-Mei, Xiao, Wen-Hua, Zhao, Hui-Xia

Journal:

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

6

A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics

Sarkar, Paramita, Yarlagadda, Venkateswarlu, Ghosh, Chandradhish, Haldar, Jayanta

Journal:

Year:

2017

Language:

english

File:

PDF, 3.96 MB

english, 2017

7

(Indolylalkyl)piperidine carbamates as inhibitors of fatty acid amide hydrolase (FAAH)

Dahlhaus, Helmut, Hanekamp, Walburga, Lehr, Matthias

Journal:

Year:

2017

Language:

english

File:

PDF, 604 KB

english, 2017

8

Protein–ligand (un)binding kinetics as a new paradigm for drug discovery at the crossroad between experiments and modelling

Bernetti, M., Cavalli, A., Mollica, L.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

9

The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors

Haffez, Hesham, Chisholm, David R., Valentine, Roy, Pohl, Ehmke, Redfern, Christopher, Whiting, Andrew

Journal:

Year:

2017

Language:

english

File:

PDF, 6.25 MB

english, 2017

10

Designing safer oral drugs

Journal:

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

11

Neuroprotective effect of single-wall carbon nanotubes with built-in peroxidase-like activity against β-amyloid-induced neurotoxicity

Shin, Jaeha, Lee, Sujin, Cha, Misun

Journal:

Year:

2017

Language:

english

File:

PDF, 1.71 MB

english, 2017

12

Identification of mitoxantrone as a new inhibitor of ROS1 fusion protein in non-small cell lung cancer cells

Luo, Lian-Xiang, Fan, Xing-Xing, Li, Ying, Peng, Xia, Ji, Yin-Chun, Hsiao, Wendy Wen-Luan, Liu, Liang, Leung, Elaine Lai-Han, Yao, Xiao-Jun

Journal:

Year:

2017

Language:

english

File:

PDF, 968 KB

english, 2017

13

Comparison of free-radical inhibiting antioxidant properties of carvedilol and its phenolic metabolites

Malig, Thomas C., Ashkin, Mitchell R., Burman, Austin L., Barday, Manuel, Heyne, Belinda J. M., Back, Thomas G.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.96 MB

english, 2017

14

Synthesis and antitumor mechanism of a new iron( iii ) complex with 5,7-dichloro-2-methyl-8-quinolinol as ligands

Zou, Bi-Qun, Qin, Qi-Pin, Bai, Yu-Xia, Cao, Qian-Qian, Zhang, Ye, Liu, Yan-Cheng, Chen, Zhen-Feng, Liang, Hong

Journal:

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

15

Multivalent ligands for the serotonin 5-HT 4 receptor

Castriconi, Federica, Paolino, Marco, Donati, Alessandro, Giuliani, Germano, Anzini, Maurizio, Mennuni, Laura, Sabatini, Chiara, Lanza, Marco, Caselli, Gianfranco, Makovec, Francesco, Sbraccia, Maria,

Journal:

Year:

2017

Language:

english

File:

PDF, 746 KB

english, 2017

16

Design, synthesis and evaluation of new ligustrazine derivatives as potential plasma-stable neuroprotective agents

Zhang, Chenze, Yan, Wenqiang, Zhao, Rui, Xu, Bing, Fang, Xiong, Yan, Mengmeng, Zhang, Yuzhong, Wang, Penglong, Lei, Haimin

Journal:

Year:

2017

Language:

english

File:

PDF, 982 KB

english, 2017

17

Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues

Verschueren, Klaas, Cobbaut, Mathias, Demaerel, Joachim, Saadah, Lina, Voet, Arnout R. D., Van Lint, Johan, De Borggraeve, Wim M.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

18

Design, synthesis and cytotoxic activity of water-soluble quinones with dibromo-p-benzoquinone cores and amino oligo(ethylene glycol) side chains against MCF-7 breast cancer cells

Scherz, Leon F., Abdel-Rahman, Engy A., Ali, Sameh S., Schlüter, A. Dieter, Abdel-Rahman, Mona A.

Journal:

Year:

2017

Language:

english

File:

PDF, 893 KB

english, 2017

19

Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease

Lattmann, E., Sattayasai, J., Narayanan, R., Ngoc, N., Burrell, D., Balaram, P. N., Palizdar, T., Lattmann, P.

Journal:

Year:

2017

Language:

english

File:

PDF, 1007 KB

english, 2017

20

68 Ga-Chelation and comparative evaluation of N,N′-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N′-diacetic acid (HBED-CC) conjugated NGR and RGD peptides as tumor targeted molecular imaging probes

Satpati, Drishty, Sharma, Rohit, Kumar, Chandan, Sarma, Haladhar Dev, Dash, Ashutosh

Journal:

Year:

2017

Language:

english

File:

PDF, 882 KB

english, 2017

21

Identification of 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I

Krishnathas, Robin, Bonke, Erik, Dröse, Stefan, Zickermann, Volker, Nasiri, Hamid R.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.58 MB

english, 2017

22

Correction: Boron-containing delocalised lipophilic cations for the selective targeting of cancer cells

Calabrese, Gianpiero, Daou, Anis, Rova, Aikaterini, Tseligka, Eirini, Vizirianakis, Ioannis S., Fatouros, Dimitrios G., Tsibouklis, John

Journal:

Year:

2017

Language:

english

File:

PDF, 113 KB

english, 2017

23

Outstanding Reviewers for MedChemComm in 2016

Journal:

Year:

2017

Language:

english

File:

PDF, 110 KB

english, 2017

24

N-tert-Prenylation of the indole ring improves the cytotoxicity of a short antagonist G analogue against small cell lung cancer

Offerman, Shaun C., Kadirvel, Manikandan, Abusara, Osama H., Bryant, Jennifer L., Telfer, Brian A., Brown, Gavin, Freeman, Sally, White, Anne, Williams, Kaye J., Aojula, Harmesh S.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.23 MB

english, 2017

25

Front cover

Journal:

Year:

2017

File:

PDF, 3.99 MB

2017

26

Back cover

Journal:

Year:

2017

File:

PDF, 2.54 MB

2017