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Volume 21; Issue 7
Main
Medicinal Chemistry Research
Volume 21; Issue 7
Medicinal Chemistry Research
Volume 21; Issue 7
1
Synthesis, antitumor and antioxidant evaluation of some new thiazole and thiophene derivatives incorporated coumarin moiety
Moustafa A. Gouda, Moged A. Berghot, Eman A. Baz, Wafaa S. Hamama
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 431 KB
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english, 2012
2
Isonicotinic acid hydrazide derivatives: synthesis, antimicrobial activity, and QSAR studies
Vikramjeet Judge, Balasubramanian Narasimhan, Munish Ahuja, Dharmarajan Sriram, Perumal Yogeeswari, Erik De Clercq, Christophe Pannecouque, Jan Balzarini
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 574 KB
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english, 2012
3
Sesquiterpene lactones: antispasmodic principles of the freshwater algaeHydrodictyon reticulatum
Rosa Martha Perez Gutierrez, Irasema Anaya sosa, Teresa Cruz y Victoria, Jose Maria Mota Flores
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 295 KB
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english, 2012
4
Simultaneous determination of sparfloxacin and commonly used H2receptor antagonists by RP-HPLC: application to in vitro drug interactions
Najma Sultana, M. Saeed Arayne, Somia Gul, Mahwish Akhtar, Sana Shamim
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 367 KB
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english, 2012
5
QSAR modeling of bifunctional quinolonyl diketo acid derivatives as integrase inhibitors
Sonal Dubey, Nahid Abbas, G. Goutham, Pradnya A. Bhosle
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 1.28 MB
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english, 2012
6
QSAR studies of aminopeptidase N/CD13 (APN) inhibitors with the scaffold 3-phenylpropane-1,2-diamine and molecular docking
Yingying Xu, Lei Zhang, Minyong Li, Wenfang Xu, Hao Fang, Luqing Shang
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 1.03 MB
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english, 2012
7
Study on synthesis of thalidomide analogues and their bioactivities; inhibition on iNOS pathway and cytotoxic effects
Chao-Bin Yeh, Pen-Yuan Lin, Jin-Ming Hwang, Chi-Jung Su, Ying-Tung Yeh, Shun-Fa Yang, Ming-Chih Chou
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 365 KB
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english, 2012
8
Design and synthesis of some pyrazole derivatives of expected anti-inflammatory and analgesic activities
Nagwa M. Abd-El Gawad, Ghaneya S. Hassan, Hanan Hanna Georgey
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 561 KB
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english, 2012
9
A novel series of homoallylic amines as potential antimicrobials
U. Sankappa Rai, Arun M. Isloor, Prakash Shetty, Nishitha Isloor, Mahesh Padaki, Hoong-Kun Fun
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 283 KB
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english, 2012
10
Assessment of antithyroid activity of 2,8-disulfanyl-1,9-dihydro-6H-purin-6-one in vitro and in vivo
Ismat Fatima, Munawar Ali Munawar, Affia Tasneem, Asmatullah, Misbahul Ain Khan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 387 KB
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english, 2012
11
Synthesis of aspirin eugenol ester and its biological activity
Jian-yong Li, Yuan-guang Yu, Qi-wen Wang, Ji-yu Zhang, Ya-jun Yang, Bing Li, Xu-zheng Zhou, Jian-rong Niu, Xiao-juan Wei, Xi-wang Liu, Zhi-qi Liu
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 255 KB
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english, 2012
12
Microwave-assisted synthesis of some novel and potent antibacterial and antifungal compounds with biological screening
Mayank Bapna, Bharat Parashar, Vinod K. Sharma, Lalit S. Chouhan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 317 KB
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english, 2012
13
Synthesis, anticancer, anti-HIV-1, and antimicrobial activity of some tricyclic triazino and triazolo[4,3-e]purine derivatives
Fawzia A. Ashour, Samia M. Rida, Soad A. M. El-Hawash, Mona M. ElSemary, Mona H. Badr
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 402 KB
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english, 2012
14
Models for anti-inflammatory activity of 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles
Rakesh K. Goyal, Harish Dureja, G. Singh, A. K. Madan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 550 KB
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english, 2012
15
Antibacterial and molecular docking studies of entagenic acid, a bioactive principle from seed kernel ofEntada pursaethaDC
Shimoga Muddappa Vidya, Venkatarangaiah Krishna, Bukkambudi Krishnaswamy Manjunatha, Kashi Prakash-Gupta Rajesh, Basavapattana Rudresh Bharath, Hanumanthappa Manjunatha
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 993 KB
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english, 2012
16
Antiviral effects of three novel derivatives of adefovir on the replication of hepatitis B virus
Di Wu, Jun-Qi Niu, Yan-Hua Ding, Xin-Yu Wu, Bo-Hua Zhong, Xiang-Wei Feng
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 572 KB
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english, 2012
17
Role of polarization in ligand docking and binding affinity prediction for inhibitors of dengue virus
Kshatresh Dutta Dubey, Amit Kumar Chaubey, Rajendra Prasad Ojha
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 730 KB
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english, 2012
18
Study on antitumor activity of metal-based diketone complexes
Kaizhi Zhang, Shusen Cui, Jingjing Wang, Xiaohong Wang, Rui Li
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 287 KB
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english, 2012
19
Antinociceptive activities of some triazole and pyrazoline moieties-bearing compounds
Ümide Demir Özkay, Özgür Devrim Can, Zafer Asım Kaplancıklı
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 276 KB
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english, 2012
20
In vitro cytotoxicity and induction of apoptosis by ruthenium(II) complexes in HL-60 and K-562
S. Bhattacharya, Subhas S. Karki, R. Suresh, L. Manikandan, G. P. Senthilkumar, M. Gupta, Upal K. Mazumder, R. Balaji, K. Murali
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 442 KB
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english, 2012
21
Dimeric 2-(2-chlorophenyl)-quinazolin-4-ones as potential antimicrobial agents
N. C. Desai, Amit Dodiya, Nayan Bhatt, Mukesh Kumar
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 286 KB
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english, 2012
22
Predicting 3H-1,2,4-triazolinones as angiotensin II receptor antagonists: 2D and 3D QSAR by kNN-molecular field analysis approach
Anupama Parate, S. C. Chaturvedi
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 766 KB
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english, 2012
23
Design, synthesis, and biological evaluation of novel 2,4-thiazolidinedione derivatives as histone deacetylase inhibitors targeting liver cancer cell line
Rhea Mohan, Ajit K. Sharma, Sanjay Gupta, C. S. Ramaa
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 557 KB
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english, 2012
24
Fast differentiation ofApocynum venetumwith related species by UPLC/MS and UPLC/SPE/NMR
Yuchi Zhang, Chunming Liu, Zhengkun Zhang, Yanjuan Qi, Guimei Wu, Sainan Li
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 362 KB
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english, 2012
25
Sucralose sweetener does not modify radiolabeling of blood constituents and morphology of red blood cells
Gabrielle de Souza Rocha, Marcia de Oliveira Pereira, Monica de Oliveira Benarroz, Jacques Natan Grinapel Frydman, Vanessa Câmara da Rocha, Mário José Pereira dos Santos, Adenilson de Souza da Fonseca
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 347 KB
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english, 2012
26
QSAR modeling of synthesized 3-(1,3-benzothiazol-2-yl) 2-phenyl quinazolin-4(3H)-ones as potent antibacterial agents
Pratibha Sharma, Ashok Kumar, Prerna Kumari, Jitendra Singh, M. P. Kaushik
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 409 KB
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english, 2012
27
Interaction studies ofE. coliuracil phosphoribosyltransferase with 5-fluorouracil for potent anti cancer activity
Vinod Kumar Yata, Kausik Sen, Mattaparthi Venkata Satish Kumar, Siddhartha Sankar Ghosh
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 540 KB
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english, 2012
28
Zn(OTf)2-catalyzed three component, one-pot cyclocondensation reaction of some new octahydroquinazolinone derivatives and access their bio-potential
Pushpak M. Shah, Manish P. Patel
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 324 KB
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english, 2012
29
Three-dimensional quantitative structure–activity relationship (3D-QSAR) analysis and molecular docking of ATP-competitive triazine analogs of human mTOR inhibitors
Karunakar Tanneeru, Bandi Madhusudhan Reddy, Lalitha Guruprasad
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 563 KB
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english, 2012
30
Synthesis, computational studies, and preliminary pharmacological evaluation of new arylpiperazines as potential antipsychotics
Sushil Kumar, A. K. Wahi, Ranjit Singh
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 373 KB
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english, 2012
31
Indazole: a medicinally important heterocyclic moiety
Ananda Thangadurai, Maninder Minu, Sharad Wakode, Shyam Agrawal, Balasubramanian Narasimhan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 684 KB
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english, 2012
32
Synthesis, characterization, and antimicrobial studies of novel 1,3,4-thiadiazolium-5-thiolates
Shahrukh T. Asundaria, Nikul S. Patel, Keshav C. Patel
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 354 KB
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english, 2012
33
Improved superaugmented eccentric connectivity indices
Rohit Dutt, Monika Singh, A. K. Madan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 1.22 MB
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english, 2012
34
Synthesis, characterization and antimicrobial evaluation of novel derivatives of isoniazid
Manav Malhotra, Sagun Sharma, Aakash Deep
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 282 KB
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english, 2012
35
Induced fit binding of aldose reductase inhibitors to AKR1B10
Anup Shah, Ranajit Shinde, Pavan Kare, V. Hymavathi, Swapnil Chavan, M. Elizabeth Sobhia
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 828 KB
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english, 2012
36
Synthesis of potential anticancer derivatives of pyrido[1,2-a]benzimidazoles
Hanan M. Refaat
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 485 KB
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english, 2012
37
Antimalarial and free radical scavenging activities of rhizomes ofPolygonatumverticillatumsupported by isolated metabolites
Haroon Khan, Muhammad Saeed, Murad Ali Khan, Inamullah Khan, Manzoor Ahmad, Naveed Muhammad, Afsar Khan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 370 KB
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english, 2012
38
Antimycobacterial activity of fractions and isolated compounds fromVetiveria zizanioides
Shikha Gupta, Gaurav R. Dwivedi, Mahendra P. Darokar, Santosh K. Srivastava
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 392 KB
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english, 2012
39
Synthesis and studies on antidepressant activity of 2′,4′,6′-trihydroxychalcone derivatives
Xin Sui, Ying-Chun Quan, Yue Chang, Rui-Peng Zhang, Yin-Feng Xu, Li-Ping Guan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 316 KB
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english, 2012
40
Antitussive effects of azepino[2,1-b]quinazolones
Kunal Nepali, Mukunda S. Bande, Sameer Sapra, Atul Garg, Sunil Kumar, Punita Sharma, Rohit Goyal, Naresh Kumar Satti, Om Parkash Suri, Kanaya Lal Dhar
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 452 KB
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english, 2012
41
Synthesis and antimicrobial activity of pyrazolinones and pyrazoles having benzothiazole moiety
Mohd. Amir, Sadique A. Javed, Mohd. Zaheen Hassan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 336 KB
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42
HPTLC method development, validation, and stress degradation studies for atorvastatin and ezetimibe in multicomponent tablet dosage form
Rajasekaran Aiyalu, Karthikeyan Mani
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 289 KB
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english, 2012
43
Synthesis and antimicrobial activity of 5-chloroindoline-2,3-dione derivatives
S. G. Shingade, Sanjaykumar B. Bari, U. B. Waghmare
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 291 KB
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english, 2012
44
Topological models for the prediction of antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines
Vikramjeet Judge, Balasubramanian Narasimhan, Munish Ahuja
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 1.03 MB
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english, 2012
45
Synthesis, spectral studies and biological evaluation of a novel series of 2-substituted-5,6-diarylsubstituted imidazo(2,1-b)-1,3,4-thiadiazole derivatives as possible anti-tubercular agents
Mahesh B. Palkar, Malleshappa N. Noolvi, Veeresh S. Maddi, Mangala Ghatole, Laxmivenkat G. Nargund
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 361 KB
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46
Novel quinolyl-thienyl chalcones and their 2-pyrazoline derivatives with diverse substitution pattern as antileishmanial agents againstLeishmania major
Syed Umar Farooq Rizvi, Hamid Latif Siddiqui, Muhammad Nisar Ahmad, Matloob Ahmad, Mujahid Hussain Bukhari
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 381 KB
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english, 2012
47
Antioxidant activities and transition metal ion chelating studies of some hydroxyl Schiff base derivatives
Ye Zhang, Biqun Zou, Kai Wang, Yingming Pan, Hong Liang, Xianghui Yi, Hengshan Wang
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 434 KB
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english, 2012
48
Blood–brain barrier permeability and transport studies of JLK1486: a new antiglioblastoma drug
Magali Barthelemy-Requin, Jérôme Nugier, Sébastien Madonna, Jean-Louis Kraus
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 359 KB
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english, 2012
49
Triptolide suppresses lipopolysaccharide-induced activity of toll-like receptor 4 in mouse macrophage cell line RAW 264.7
Weiwei Jiang, Weibing Tang, Qiming Geng, Xiaoqun Xu
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 413 KB
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english, 2012
50
Synthesis and antihyperlipidemic efficiency of berberine-based HMG-CoA reductase inhibitor
Xiaoli Ye, Kai He, Xiaokang Zhu, Baoshun Zhang, Xin Chen, Jun Yi, Xuegang Li
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 577 KB
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english, 2012
51
An electronic study of pyrazolones drugs on agranulocytosis
J. Rodrigues Silva, A. Noronha Queiroz, E. A. Fontes Junior, M. V. Santos Silva, A. Manoel Herculano, A. M. J. Chaves Neto, R. Santos Borges
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 457 KB
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english, 2012
52
Synthesis of novel pyrazole and pyrimidine derivatives bearing sulfonamide moiety as antitumor and radiosensitizing agents
Mostafa M. Ghorab, Fatma A. Ragab, Helmy I. Heiba, Hanan A. Youssef, Marwa G. El-Gazzar
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 334 KB
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english, 2012
53
Potential applications of violacein: a microbial pigment
Marcela Durán, Alexandre N. Ponezi, Adelaide Faljoni-Alario, Maria F. S. Teixeira, Giselle Z. Justo, Nelson Durán
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 256 KB
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english, 2012
54
Design, synthesis, and docking studies of novel ofloxacin analogues as antimicrobial agents
S. Jubie, P. Prabitha, R. Rajesh Kumar, R. Kalirajan, R. Gayathri, S. Sankar, K. Elango
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 770 KB
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english, 2012
55
Synthesis and evaluation of antioxidant and antimicrobial properties of thymol containing pyridone moieties
P. S. Nagle, Y. A. Pawar, A. E. Sonawane, S. M. Bhosale, D. H. More
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 427 KB
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english, 2012
56
Formulation of cashew nut shell liquid (CSNL) nanoemulsion, a potent inhibitor of human MCF-7 breast cancer cell proliferation
Amal Al-Hazzani, Vaiyapuri Periyasamy, Pandurangan Subash-Babu, Ali A. Alshatwi
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 429 KB
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english, 2012
57
Isolation and characterization ofn-octacosanoic acid fromViburnum foetens: a novel antibiofilm agent againstStreptococcus Mutans
Rosina Khan, Zakia Khanam, Asad U. Khan
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 373 KB
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english, 2012
58
Effect of complexation of 3-aminoquinoxaline-2-carbonitrile 1,4-dioxides with palladium and copper on their anti-T. cruziactivity
Diego Benítez, María L. Lavaggi, Dinorah Gambino, María H. Torre, Hugo Cerecetto, Mercedes González
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 350 KB
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english, 2012
59
Synthesis, antimicrobial, antioxidant, anti-inflammatory, and analgesic activities of some new 3-(2′-thienyl)pyrazole-based heterocycles
Bakr F. Abdel-Wahab, Hassan Abdel-Gawad, Ghada E. A. Awad, Farid A. Badria
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 401 KB
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english, 2012
60
3D QSAR, docking studies, and pharmacophore modeling of selected factor Xa inhibitors
P. B. Choudhari, M. S. Bhatia
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 421 KB
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english, 2012
61
Evaluation of biological effects of the naproxen
Marcia de Oliveira Pereira, Gabrielle de Souza Rocha, Aldo Cunha Medeiros, Adenilson de Souza da Fonseca, Mario Bernardo-Filho
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 252 KB
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english, 2012
62
Kinetic studies of novel inhibitors of endomorphin degrading enzymes
Renata Perlikowska, Jakub Fichna, Jean Claude do-Rego, Katarzyna Gach, Anna Janecka
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 276 KB
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english, 2012
63
Synthesis and antimicrobial evaluation of novel benzo[b]thiophenes comprising β-lactam nucleus
Amit R. Trivedi, Jignesh M. Desai, Bipin H. Dholariya, Dipti K. Dodiya, Viresh H. Shah
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 359 KB
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english, 2012
64
Conventional and microwave techniques for synthesis and antimicrobial studies of novel 1-[2-(2-chloro(3-quinolyl))-5-(4-nitrophenyl)-(1,3,4-oxadiazolin-3-yl)]-3-(aryl)prop-2-en-1-ones
N. C. Desai, Amit M. Dodiya
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 342 KB
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english, 2012
65
New antiepileptic agents: structure–activity relationships
Pooja S. Banerjee, P. K. Sharma
Journal:
Medicinal Chemistry Research
Year:
2012
Language:
english
File:
PDF, 1.83 MB
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english, 2012
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