Volume 22; Issue 8

Medicinal Chemistry Research

Volume 22; Issue 8

1

Chem-bioinformatics and in vitro approaches for candidate optimization: a case study of NSC745689 as a promising antitumor agent

Nandekar, Prajwal P., Tumbi, Khaled M., Bansal, Nitu, Rathod, Vijay P., Labhsetwar, Leena B., Soumya, Neelagiri, Singh, Sushma, Sangamwar, Abhay T.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 1.33 MB

english, 2013

2

In silico design of peptidomimetics for PKC-β II inhibition: perspectives for diabetic cardiomyopathy therapy

Rohit, Shishir, Balupuri, Anand, Sobhia, M. Elizabeth

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 573 KB

english, 2013

3

Synthesis and antitumor activity of new pyrido[2,3-d]pyrimidine derivatives

Gineinah, Magdy M., Nasr, Magda N. A., Badr, Sahar M. I., El-Husseiny, Walaa M.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 352 KB

english, 2013

4

Design and synthesis of new N-substituted amino methyl-[1,2,3] triazolyl moieties of fluoroquinolones as antibacterial agents

Govinda Rajulu, G., Bhojya Naik, Halehatty S., Viswanathan, Abhilash, Agarwal, Devesh S., Sambasivam, Ganesh, Koppolu, Kesavan Poonimangadu

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 779 KB

english, 2013

5

Synthesis of some new 3,5-diamino-4-(4′-fluorophenylazo)-1-aryl/heteroarylpyrazoles as antimicrobial agents

Aggarwal, Ranjana, Kumar, Virender, Gupta, Girish Kumar, Kumar, Vinod

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 524 KB

english, 2013

6

Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice

Mathew, Bijo, Suresh, Jerad, Vinod, Devaraji

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 315 KB

english, 2013

7

Synthesis and biological evaluation of new [1,3,4]thiadiazepino[7,6-b]quinolin-2-amines as potent anti-microbial agents

Raza, Hasnain Muhammad, Rizvi, Nada-E-Ali, Siddiqui, Hamid Latif, Javaid, Arshad, Iqbal, Mazhar

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 470 KB

english, 2013

8

Apoptotic effects of some carbazole derivatives on lung carcinoma and glioma cell lines

ÃiftÃ§i, GÃ¼lÅen AkalÄ±n, Temel, Halide Edip, YÄ±ldÄ±rÄ±m, Åafak Ulusoylar, KaplancÄ±klÄ±, Zafer AsÄ±m, AltÄ±ntop, Mehlika Dilek, GenÃ§, LÃ¼tfi

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 579 KB

english, 2013

9

Synthesis and cytotoxicity of novel 6H-indolo[2,3-b]quinoxaline derivatives

Avula, Sreenivas, Komsani, Jayaram Reddy, Koppireddi, Satish, Yadla, Rambabu, Kanugula, Anantha KoteswaraRao, Kotamraju, Srigiridhar

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 285 KB

english, 2013

10

Synthesis and biologic evaluation of new 3-phenoxyazetidin-2-one derivatives as selective cyclooxygenase-2 inhibitors

Arefi, H., Zarghi, A.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 332 KB

english, 2013

11

Synthesis of new quinoline-2-pyrazoline-based thiazolinone derivatives as potential antimicrobial agents

Desai, N. C., Joshi, V. V., Rajpara, K. M.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 346 KB

english, 2013

12

Synthesis, antitubercular activity, and QSAR analysis of substituted nitroaryl analogs: chalcone, pyrazole, isoxazole, and pyrimidines

Gupta, Revathi A., Kaskhedikar, Satish G.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 759 KB

english, 2013

13

Docking, synthesis, and pharmacological investigation of novel substituted thiazole derivatives as non-carboxylic, anti-inflammatory, and analgesic agents

Thore, S. N., Gupta, Sunil V., Baheti, Kamalkishor G.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 390 KB

english, 2013

14

Synthesis of novel 4-thiazolidione derivatives as antibacterial agents against drug-resistantStaphylococcus epidermidis

Zhao, Dan, Liu, Huayong, Zheng, Likang, He, Guozhen, Qu, Di, Han, Shiqing

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 279 KB

english, 2013

15

Synthesis, antimalarial-, and antibacterial activity evaluation of some new 4-aminoquinoline derivatives

Rudrapal, Mithun, Chetia, Dipak, Prakash, Anil

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 288 KB

english, 2013

16

Benzimidazole derivatives: synthesis, leishmanicidal effectiveness, and molecular docking studies

Shaukat, Awais, Mirza, Hira M., Ansari, Amna H., Yasinzai, Masoom, Zaidi, Sohail Z., Dilshad, Sana, Ansari, Farzana L.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 739 KB

english, 2013

17

Synthesis, antioxidant, and antitumor evaluation of certain newN-substituted-2-amino-1,3,4-thiadiazoles

Hamama, Wafaa S., Gouda, Moustafa A., Badr, Marwa H., Zoorob, Hanafi H.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 532 KB

english, 2013

18

Synthesis of some new indolo[2,3-c]isoquinolinyl pyrazoles, -1,3,4-oxadiazoles and their biological activities

Saundane, Anand R., Verma, Vaijinath A., Vijaykumar, Katkar

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 397 KB

english, 2013

19

Synthesis and biologic activities of some novel heterocyclic chalcone derivatives

Sharma, Punita, Kumar, Suresh, Ali, Furquan, Anthal, Sumati, Gupta, Vivek K., Khan, Inshad A., Singh, Surjeet, Sangwan, Payare L., Suri, Krishan A., Gupta, Bishan D., Gupta, Devinder K., Dutt, Prabhu,

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 480 KB

english, 2013

20

Synthesis and comparative bioefficacy ofN-(1-phenethyl-4-piperidinyl)propionanilide (fentanyl) and its 1-substituted analogs in Swiss albino mice

Gupta, Pradeep Kumar, Yadav, Shiv Kumar, Bhutia, Yangchen Doma, Singh, Poonam, Rao, Pooja, Gujar, Niranjan Laxman, Ganesan, Kumaran, Bhattacharya, Rahul

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 330 KB

english, 2013

21

Novel PCU cage diol peptides as potential targets against wild-type CSA HIV-1 protease: synthesis, biological screening and molecular modelling studies

Karpoormath, Rajshekhar, Sayed, Yasien, Govender, Thavendran, Kruger, Hendrik G., Soliman, Mahmoud E. S., Maguire, Glenn E. M.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 805 KB

english, 2013

22

Microwave-assisted synthesis of novel 4H-chromene derivatives bearing 2-aryloxyquinoline and their antimicrobial activity assessment

Sangani, Chetan B., Shah, Nimesh M., Patel, Manish P., Patel, Ranjan G.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 341 KB

english, 2013

23

Drug interactions and synthesis of cefpirome with hypoglycemic agents

Nawaz, Muhammad, Arayne, Muhammad Saeed, Sultana, Najma

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 371 KB

english, 2013

24

Design, synthesis, and cytotoxic activities of new 2,4,5-triarylimidazoles

Zarghi, A., Arfaei, S., Shirazi, F. H.

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 369 KB

english, 2013

25

Syntheses and in vitro biological screening of 1-aryl-10H-[1,2,4]triazolo[3′,4′:3,4][1,2,4]triazino[5,6-b]indoles

Upadhyay, Kuldip, Manvar, Atul, Loddo, Roberta, Colla, Paolo La, Virsodiya, Vijay, Trivedi, Jalpa, Chaniyara, Ravi, Shah, Anamik

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 396 KB

english, 2013

26

Molecular modeling studies on 3,4-dihydroquinazolines as trypanothione reductase inhibitors using 3D-QSAR and docking approaches

Zhi-Xiong Ruan, De-Sheng Huangfu, Ping-Hua Sun…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

27

Evaluating anti-Toxoplasmagondiiactivity of new serie of phenylsemicarbazone and phenylthiosemicarbazones in vitro

Marco Antônio G. B. Gomes, Laís P. Carvalho…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 394 KB

english, 2013

28

Challenges in docking 2′-hydroxy and 2′,4′-dihydroxychalcones into the binding site of ALR2

Sorin I. Avram, Luminita Crisan, Liliana M. Pacureanu…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 726 KB

english, 2013

29

Novel salicylamide derivatives incorporating neonicotinoid pharmacophore: design, synthesis, characterization, and biological evaluation

Shaoyong Ke, Zhigang Zhang, Tong Long, Ying Liang…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 367 KB

english, 2013

30

Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus

Hakan Bektaş, Şule Ceylan, Neslihan Demirbaş…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 359 KB

english, 2013

31

Synthesis, molecular docking studies, and in vitro screening of sulfanilamide-thiourea hybrids as antimicrobial and urease inhibitors

Aamer Saeed, Sumera Zaib, Arshid Pervez, Amara Mumtaz…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 676 KB

english, 2013

32

Erratum to: Syntheses and in vitro biological screening of 1-aryl-10H-[1,2,4]triazolo[3′,4′:3,4][1,2,4]triazino[5,6-b]indoles

Kuldip Upadhyay, Atul Manvar, Vijay Virsodiya…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 149 KB

english, 2013

33

Antibacterial and antifungal screening of newly synthesized benzimidazole-clubbed chalcone derivatives

Kalpesh Parikh, Deepkumar Joshi

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 359 KB

english, 2013

34

Trypsin inhibitory potential and microbial transformation of rutin isolated fromCitrus sinensis

Muhammad Asam Raza, Durre Shahwar

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 342 KB

english, 2013

35

Synthesis and biological evaluation of novel condensed pyrimidinylmethylsulfinylbenzimidazoles as antiulcer agent

Prashik B. Dudhe, Kishor S. Jain, Vikas K. Raskar…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 398 KB

english, 2013

36

Synthesis and biological evaluation of novel hydroquinone dimethyl ethers as potential anticancer and antimicrobial agents

Ibrahim Chaaban, El Sayeda M. El Khawass, Mona A. Mahran…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 415 KB

english, 2013

37

Novel 2-(E)-substituted benzylidene-6-(N-substituted aminomethyl)cyclohexanones and cyclohexanols as analgesic and anti-inflammatory agents

Dan Liu, Weishe Yu, Jingjing Li, Cong Pang, Linxiang Zhao

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 358 KB

english, 2013

38

Pharmacophore modeling, 3D-QSAR, and molecular docking study on naphthyridine derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1

Palani Kirubakaran, Karthikeyan Muthusamy…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 601 KB

english, 2013

39

Isolation of terrestribisamide fromPeltophorum pterocarpum(DC.) Baker ex. K. Heyne and its antimicrobial, antioxidant, and cytotoxic activities

M. Karunai Raj, C. Balachandran, V. Duraipandiyan…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 497 KB

english, 2013

40

Synthesis and cytotoxic activity of diaryl urea derivatives with a 4-methylpiperazinylcarbonyl moiety

Wei Xuan, Wen Ding, Hong-xiang Hui, San-qi Zhang

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 294 KB

english, 2013

41

Virtual screening and biochemical evaluation of the inhibitors of dual-specificity phosphatase 26

Hwangseo Park, Ayoung Kyung, Hyun-Ju Lee, Sunghyun Kang…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 395 KB

english, 2013

42

Antibacterial and antifungal oxovanadium(IV) complexes of triazole-derived Schiff bases

Sajjad H. Sumrra, Zahid H. Chohan

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 449 KB

english, 2013

43

Inhibition of Cathepsin D protease activity byPunica granatumfruit peel extracts, isolates, and semisynthetic analogs

Amit K. Chaturvedi, Suaib Luqman, Vijaya Dubey…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 269 KB

english, 2013

44

Thiourea and thioether derivatives of sorafenib: synthesis, crystal structure, and antiproliferative activity

Jianwen Yao, Jing Chen, Zuopeng He, Wei Sun, Hao Fang…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 1.51 MB

english, 2013

45

Anti-inflammatory and analgesic activities of a new cucurbitacin isolated fromCitrullus colocynthisseeds

Belsem Marzouk, Mohamed Ali Mahjoub, Abderrahman Bouraoui…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 258 KB

english, 2013

46

Synthesis ofd-amino acid peptides and their effect on beta-amyloid aggregation and toxicity in transgenicCaenorhabditis elegans

Seema Jagota, Jayakumar Rajadas

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 559 KB

english, 2013

47

Cytotoxicity and QSAR study of (thio)ureas derived from phenylalkylamines and pyridylalkylamines

Ratchanok Pingaew, Pan Tongraung, Apilak Worachartcheewan…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 764 KB

english, 2013

48

In vitro cytotoxicity, antimicrobial, and metal-chelating activity of triterpene saponins from tea seed grown in Kangra valley, India

Robin Joshi, Swati Sood, Poonam Dogra, Madhvi Mahendru…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 457 KB

english, 2013

49

Partition coefficient determination of a series of isoindolines-2-substituted and its correlation with their antiproliferative activity on HeLa cells

Cynthia R. Trejo Muñoz, Teresa Mancilla Percino…

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 338 KB

english, 2013

50

Non-imidazole histamine H3ligands: part V. synthesis and preliminary pharmacological investigation of 1-[2-thiazol-4-yl- and 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives

Guryn, Roman, Staszewski, Marek, Walczyński, Krzysztof

Journal:

Medicinal Chemistry Research

Year:

2013

Language:

english

File:

PDF, 389 KB

english, 2013