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Volume 23; Issue 1
Main
Medicinal Chemistry Research
Volume 23; Issue 1
Medicinal Chemistry Research
Volume 23; Issue 1
1
POM analyses for antimicrobial evaluation of thienopyrimidinones derivatives: a rapid method for drug design
Hadda, Taibi Ben
,
Ahmad, Mushtaq
,
Sultana, Shazia
,
Shaheen, Usama
,
Bader, Ammar
,
Srivastava, Sajal
,
Das, Barnali
,
Salgado-Zamora, Héctor
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 357 KB
Your tags:
english, 2014
2
Impact of ABC transporters, glutathione conjugates in MDR and their modulation by flavonoids: an overview
Gupta, Vinay Kumar
,
Bhalla, Yashika
,
Jaitak, Vikas
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 980 KB
Your tags:
english, 2014
3
Synthesis, evaluation and docking studies on steroidal pyrazolones as anticancer and antimicrobial agents
Shamsuzzaman,
,
Mashrai, Ashraf
,
Ahmad, Anis
,
Dar, Ayaz Mahmood
,
Khanam, Hena
,
Danishuddin, Mohd
,
Khan, Asad U.
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 694 KB
Your tags:
english, 2014
4
Molecular docking and quantitative structure–activity relationship (QSAR) analyses of indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors
Masand, Vijay H.
,
Mahajan, Devidas T.
,
Hadda, Taibi Ben
,
Jawarkar, Rahul D.
,
Chavan, Hemant
,
Bandgar, B. P.
,
Chauhan, Harsh
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 947 KB
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english, 2014
5
Two- and three-dimensional QSAR studies on a set of antimycobacterial pyrroles: CoMFA, Topomer CoMFA, and HQSAR
Joshi, Shrinivas D.
,
More, Uttam A.
,
Aminabhavi, Tejraj M.
,
Badiger, Aravind M.
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 2.87 MB
Your tags:
english, 2014
6
Pharmacophore and QSAR modeling of some structurally diverse azaaurones derivatives as anti-malarial activity
Sharma, Mukesh C.
,
Sharma, Smita
,
Sharma, Pratibha
,
Kumar, Ashok
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 830 KB
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english, 2014
7
A potent cytotoxic metabolite from terrestrial actinomycete,Streptomyces collinus
Rather, S. A.
,
Kumar, Sunil
,
Rah, Bilal
,
Arif, Mohammad
,
Ali, Asif
,
Qazi, Parvaiz
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 490 KB
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english, 2014
8
Synthesis and evaluation of isonicotinoyl hydrazone derivatives as antimycobacterial and anticancer agents
Naveen Kumar, H. S.
,
Parumasivam, Thaigarajan
,
Jumaat, Fatimah
,
Ibrahim, Pazilah
,
Asmawi, Mohd. Zaini
,
Sadikun, Amirin
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 1.13 MB
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english, 2014
9
Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings
Hayashi, Shigeo
,
Ohashi, Katsuyo
,
Nakata, Eriko
,
Emoto, Chie
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 3.56 MB
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english, 2014
10
Erratum to: Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings
Hayashi, Shigeo
,
Ohashi, Katsuyo
,
Nakata, Eriko
,
Emoto, Chie
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 154 KB
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english, 2014
11
Synthesis and antitumor activity of certain new thiazolo[2,3-b]quinazoline and thiazolo[3,2-a]pyrimidine analogs
Hassan, Ghada S.
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 419 KB
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english, 2014
12
Antimicrobial and antiquorum-sensing studies. Part 2: synthesis, antimicrobial, antiquorum-sensing and cytotoxic activities of new series of fused [1,3,4]thiadiazole and [1,3]benzothiazole derivatives
El-Gohary, N. S.
,
Shaaban, M. I.
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 412 KB
Your tags:
english, 2014
13
Synthesis, characterization, and antitumor activities of 1,1′-diacetylferrocene dihydrazone containing phenolic group and its complexes with Pd(II) and Pt(II)
Wael Hussein Hegazy, Yasair Suliman Al-Faiyz
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 401 KB
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english, 2014
14
Novel ibuprofen prodrugs with improved pharmacokinetics and non-ulcerogenic potential
Valmik D. Dhakane, Hemant V. Chavan, Vishnu N. Thakare…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 586 KB
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english, 2014
15
Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives
Fatma Zilifdar, Sabiha Alper-Hayta, Serap Yilmaz…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 309 KB
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english, 2014
16
Modification of carboxylated multiwall nanotubes with benzotriazole derivatives and study of their anticancer activities
Mahdieh Entezari, Mojdeh Safari, Malak Hekmati…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 832 KB
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17
Synthesis and in vitro evaluation of antifungal and cytotoxic activities of eugenol glycosides
Thiago Belarmino de Souza, Marina Orlandi…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 312 KB
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english, 2014
18
Schiff’s base derivatives bearing 2-thiophenoxyquinoline nucleus as new antibacterial agents
Jigar A. Makawana, Chetan B. Sangani, Shashikant B. Teraiya…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 341 KB
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english, 2014
19
Synthesis and biological evaluation of novel 2′,4′,5′-trimethoxyflavonol derivatives as anti-inflammatory and antimicrobial agents
Girish D. Hatnapure, Ashish P. Keche, Atish H. Rodge…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 413 KB
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english, 2014
20
Chemical composition ofHypogymnia physodeslichen and biological activities of some its major metabolites
Branislav Ranković, Marijana Kosanić, Nedeljko Manojlović…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 425 KB
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english, 2014
21
Synthesis and antibacterial evaluation of furan derivatives bearing a rhodanine moiety
Jian Che, Chang-Ji Zheng, Ming-Xia Song, Ya-Jing Bi, Yi Liu…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 411 KB
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english, 2014
22
Synthesis, characterization, and in vitro antimicrobial evaluation of new 5-chloro-8-bromo-3-aryl-1,2,4-triazolo[4,3-c]pyrimidines
Basavapatna N. Prasanna Kumara, Kikkeri N. Mohana…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 1.18 MB
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english, 2014
23
Effect on α-glucosidase inhibition and antioxidant activities of butyrolactone derivatives fromAspergillus terreusMC751
Rizna Triana Dewi, Sanro Tachibana, Ahmad Darmawan
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 403 KB
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english, 2014
24
Design, synthesis, and in vitro antibacterial screening of some novel 3-pentyloxy-1-hydroxyxanthone derivatives
Aparoop Das, Md. Mutahar Shaikh, Srabanti Jana
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 768 KB
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english, 2014
25
Anti-HIV-1 screening of (2E)-3-(2-chloro-6-methyl/methoxyquinolin-3-yl)-1-(aryl)prop-2-en-1-ones
Syed Umar Farooq Rizvi, Matloob Ahmad…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 419 KB
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26
Synthesis, physicochemical properties, antimicrobial and antioxidant studies of pyrazoline derivatives bearing a pyridyl moiety
Imtiyaz Hussain Lone, Khaliquz Zaman Khan…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 312 KB
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english, 2014
27
Pharmacophore combination as a useful strategy to discover new antitubercular agents
Dharmarajsinh N. Rana, Mahesh T. Chhabria, Nisha K. Shah…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 495 KB
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english, 2014
28
Chemical transformation of ∆9(15)-africanene and their antibacterial activity
S. Rajaram, A. Vijender Reddy, P. Krishnaiah, K. Ravinder…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 261 KB
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english, 2014
29
Optimization of antifungal production from a novel strainStreptomycessp. TKJ2 using response surface methodology
Abdelaziz Messis, Azzeddine Bettache, Anissa Brahami…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 487 KB
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english, 2014
30
Design, synthesis, in silico, and in vitro evaluation of novel pyrimidine phosphonates with cytotoxicity against breast cancer cells
Nanda Kumar Yellapu, Navya Atluri, Kalpana Kandlapalli…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 662 KB
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english, 2014
31
Transition metal complexes ofs-triazine derivative: new class of anticonvulsant, anti-inflammatory, and neuroprotective agents
R. Shanmugakala, P. Tharmaraj, C. D. Sheela…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 653 KB
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english, 2014
32
Some substituted 1,3,4-thiadiazoles: a novel centrally acting agents
Rajesh Sharma, Yogendra Prasad, Ganesh Prasad Mishra…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 297 KB
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english, 2014
33
Synthesis, characterization and antimicrobial studies of a few novel thiazole derivatives
Aletti S. Praveen, Hemmige S. Yathirajan, Badiadka Narayana…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 2.58 MB
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34
Computational evaluation and experimental verification of antibacterial and antioxidant activity of 7-hydroxy-3-pyrazolyl-4H-chromen-4-ones and theiro-glucosides: identification of pharmacophore sites
Javed Sheikh, Kishor Hatzade, Ammar Bader, Usama Shaheen…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 617 KB
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english, 2014
35
Antioxidant and antimicrobial activities of novel quinazolinones
Ahmed A. Al-Amiery, Abdul Amir H. Kadhum, Mohammed Shamel…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 534 KB
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english, 2014
36
DNA-binding and cleavage, cytotoxicity properties of Ru(II) complexes with 2-(4′-chloro-phenyl) imidazo[4,5-f][1,10]phenanthroline, ligand and their “light switch” on–off effect
Nazar Mohammed Gabra, Bakheit Mustafa, Yata Praveen Kumar…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 680 KB
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english, 2014
37
Anti-mycobacterial, cytotoxic activities ofKnoevenageland (E)-α,β-unsaturated esters and ketones from 2-chloronicotinaldehydes
Pathi Suman, Rayala Nageswara Rao, Bhimapaka China Raju…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 410 KB
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english, 2014
38
Design and evaluation of new hybrid pharmacophore quinazolino-tetrazoles as anticonvulsant strategy
Sachin Malik, Suroor A. Khan
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 477 KB
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english, 2014
39
In vitro and in silico biological studies of novel thiazolo[3,2-a]pyrimidine-6-carboxylate derivatives
Kundapura Umesha, Balladka K. Sarojini…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 665 KB
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english, 2014
40
Design, synthesis and structure–activity relationship of new HSL inhibitors guided by pharmacophore models
Jumana D. Al-Shawabkeh, Afaf H. Al-Nadaf, Lina A. Dahabiyeh…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 1.24 MB
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english, 2014
41
Synthesis and antibacterial activity of 4,4′-(aryl or alkyl methylene)-bis(1H-pyrazol-5-ol) derivatives
S. Bhavanarushi, V. Kanakaiah, Gandu Bharath…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 327 KB
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english, 2014
42
Efficient synthesis, anticonvulsant and muscle relaxant activities of new 2-((5-amino-1,3,4-thiadiazol-2-yl)methyl)-6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives
Bhawna Sharma, Amita Verma, Upendra Kumar Sharma…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 458 KB
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english, 2014
43
Synthesis, evaluation, and molecular docking studies of cycloalkyl/aryl-3,4,5-trimethylgallates as potent non-ulcerogenic and gastroprotective anti-inflammatory agents
Mamta Sachdeva Dhingra, Pran Kishore Deb, Renu Chadha…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 1.07 MB
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english, 2014
44
Synthesis, molecular docking of novel 1,8-naphthyridine derivatives and their cytotoxic activity against HepG2 cell lines
Ahmad F. Eweas, Nagy M. Khalifa, Nisreen S. Ismail…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 616 KB
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english, 2014
45
QSAR study of IKKβ inhibitors by the genetic algorithm: multiple linear regressions
Eslam Pourbasheer, Reza Aalizadeh, Mohammad Reza Ganjali…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 451 KB
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english, 2014
46
Pyridazine and its related compounds. Part 34. Hypoglycemic and hypolipidemic activity of some novel condensed pyridazine sulfonamides
Ali Deeb, Wafaa El-Eraky, Sally El-Awdan, Sebaey Mahgoub
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 360 KB
Your tags:
english, 2014
47
Ligand-based 3D-QSAR analysis and virtual screening in exploration of new scaffolds asPlasmodium falciparumglutathione reductase inhibitors
P. Kamaria, N. Kawathekar
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 577 KB
Your tags:
english, 2014
48
Novel 3-benzyl-2,6-diarylpiperidin-4-one derivatives: syntheses, characterization, and antimicrobial profile
Shashi Kant Sahu, Avinash C. Tripathi, Mary Koshy…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 312 KB
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english, 2014
49
Solvent-free, one-pot synthesis and biological evaluation of some new dipyrazolo [3,4-b:4′,3′-e]pyranylquinolones and their precursors
Narsidas J. Parmar, Bhavesh R. Pansuriya…
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 453 KB
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english, 2014
50
A common binding mode
Chen, Jiao
,
Liu, Yifang
,
Cheng, Tianyi
,
Lao, Xingzhen
,
Gao, Xiangdong
,
Zheng, Heng
,
Yao, Wenbing
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 1.06 MB
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english, 2014
51
Molecular dynamics simulation of DNA duplex, analog of PPT (polypurine tract), its conformation and hydration: a theoretical study
Ramesh Kumar Yadav,Umesh Yadava
Journal:
Medicinal Chemistry Research
Year:
2014
Language:
english
File:
PDF, 579 KB
Your tags:
english, 2014
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