Volume 23; Issue 9

Medicinal Chemistry Research

Volume 23; Issue 9

1

Molecular docking studies of chromone derivatives against wild type and mutant strains of HIV-1 protease

P. Nunthanavanit, J. Ungwitayatorn

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

2

Synthesis and in vitro anticancer activity of brevifoliol derivatives substantiated by in silico approach

Kaur, Ranjeet, Chattopadhyay, Sunil K., Chatterjee, Arnab, Prakash, Om, Khan, Feroz, Suri, Nitasha, Priya, Dev, Saxena, A. K.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 2.01 MB

english, 2014

3

Anti-asthmatic activity of azepino [2, 1-b] quinazolones, synthetic analogues of vasicine, an alkaloid fromAdhatoda vasica

Rayees, Sheikh, Satti, Naresh Kumar, Mehra, Rukmankesh, Nargotra, Amit, Rasool, Shafaq, Sharma, Anjna, Sahu, Promod Kumar, Rajnikant,, Gupta, Vivek K., Nepali, Kunal, Singh, Gurdarshan

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

4

Comparative modeling and molecular docking studies ofd-Alanine:d-alanine ligase: a target of antibacterial drugs

Syed Sikander Azam,Sumra Wajid Abbasi,Amina Saleem Akhtar…

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 2.72 MB

english, 2014

5

Synthesis, molecular docking and antibacterial evaluation of various quinoline schiff bases: labeling and biodistribution of99mTc-2-(p-hydroxybenzylidene)-1-(quinolin-4-yl) hydrazine

Al-wabli, Reem I., Khedr, Mohammed A., Kadi, Adnan A., Motaleb, Mohammed A., Al-rashood, Khalid A., Zaghary, Wafaa A.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 689 KB

english, 2014

6

Synthesis, characterization of new imidazoquinonyl chalcones and pyrazolines as potential anticancer and antioxidant agents

Dinesha,, Viveka, Shivapura, Naik, Prashantha, Nagaraja, Gundibasappa Karikannar

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 352 KB

english, 2014

7

Design and synthesis of lupeol analogues and their in vitro PTP-1B inhibitory activity

Khan, Mohammad F., Mishra, Devendra P., Ramakrishna, E., Rawat, Arun K., Mishra, Akansha, Srivastava, Arvind K., Maurya, Rakesh

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 641 KB

english, 2014

8

Structure-based 3D-QSAR studies on quinazoline derivatives as platelets-derived growth factor (PDGFR) inhibitors

Ul-Haq, Zaheer, Zafar, Syed Kashif, Khan, Naveed, Mahmood, Uzma

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 2.31 MB

english, 2014

9

Essential aminoacid incorporated GABA–phthalimide derivatives: synthesis and anticonvulsant evaluation

Ahuja, Priya, Husain, Asif, Siddiqui, Nadeem

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

10

Efficient synthesis of heterocyclic compounds derived from 2,6-dioxopiperazine derivatives and their evaluation for anti-inflammatory and anticancer activities

Kumar, Sandeep, Kumar, Nikhil, Roy, Partha, Sondhi, Sham M.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 12.30 MB

english, 2014

11

Evaluation of phytocannabinoids from high-potencyCannabis sativausing in vitro bioassays to determine structure–activity relationships for cannabinoid receptor 1 and cannabinoid receptor 2

Husni, Afeef S., McCurdy, Christopher R., Radwan, Mohamed M., Ahmed, Safwat A., Slade, Desmond, Ross, Samir A., ElSohly, Mahmoud A., Cutler, Stephen J.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 366 KB

english, 2014

12

Hybrid probes of aromatic amine and barbituric acid: highly promising leads for anti-bacterial, anti-fungal and anti-cancer activities

Dhorajiya, Bhaveshkumar D., Dholakiya, Bharatkumar Z., Mohareb, Rafat M.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 404 KB

english, 2014

13

Synthesis, antimicrobial, and anticancer evaluation of novel 2-(3-methylindolyl)benzimidazole derivatives

Kishore Babu, P. N., Ramadevi, B., Poornachandra, Y., Ganesh Kumar, C.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 576 KB

english, 2014

14

Hantzsch and Schiff’s reaction: synthesis, in vitro cytotoxic and antimicrobial activity of [1,3,4]oxadiazoline and [1,3]thiazole derivatives

Chidananda, N., Poojary, Boja, Sumangala, V., Suchetha Kumari, N., Unnikrishnan,

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 802 KB

english, 2014

15

Design and syntheses of some new quinoxaline derivatives containing pyrazoline residue as potential antimicrobial agents

Kumar, Jagdish, Chawla, Gita, Kumar, Umesh, Sahu, Kapendra

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 496 KB

english, 2014

16

Microwave-assisted synthesis of benzimidazole bearing 1,3,4-oxadiazole derivatives: screening for their in vitro antimicrobial activity

Desai, N. C., Kotadiya, G. M.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 382 KB

english, 2014

17

Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention

Aboul-Fadl, Tarek, Al-Hamad, Suliman S., Lee, Kevin, Li, Nan, Gary, Bernard D., Keeton, Adam B., Piazza, Gary A., Abdel-Hamid, Mohammed K.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 3.12 MB

english, 2014

18

Synthesis and evaluation of 2-(2-((4-substituted-phenoxy)methyl)-1H-benzo[d] imidazol-1-yl)acetohydrazone derivatives as antitumor agents

Li, Zicheng, Zhang, Sicheng, Deng, Lei, Hu, Jing, Li, Huan, Zhao, Yinglan, Luo, Youfu, Huang, Wencai

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

19

Synthesis, characterization, in vitro antimicrobial, and anthelmintic evaluations of 2-(4-chloro-3-methylphenoxy)-N′-[{5′-(substituted aryl)-furan-2′-yl}-methylidene]-acetohydrazides

Varshney, Munendra Mohan, Husain, Asif, Parcha, Versha

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 370 KB

english, 2014

20

Theoretical approaches to identify the potent scaffold for human sirtuin1 activator: Bayesian modeling and density functional theory

Sakkiah, Sugunadevi, Arooj, Mahreen, Lee, Keun Woo, Torres, Jorge Z.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 2.69 MB

english, 2014

21

A benzimidazopyridoquinoxaline as promising scaffold for G-quadruplex DNA targeting

Zanzoul, Asmae, Ramli, Youssef, Essassi, El Mokhtar, Pratviel, Geneviève

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

22

Synthesis, characterization, and DNA cleavage study of dehydroacetic acid based tridentate Schiff’s base and its metal complexes of first transition series

Pal, R., Kumar, V., Gupta, A. K., Beniwal, V., Gupta, G. K.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 490 KB

english, 2014

23

Synthesis of highly potent piperazine-linked benzothiazolyl-4-thiazolidinones via catalyticN-formylation: antibacterial drug design

Patel, Rahul V., Park, Se Won

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 398 KB

english, 2014

24

Design, synthesis and docking studies of 2-benzoxazolinone-based 1,2,4-triazoles as proinflammatory cytokine inhibitors

Haider, Saqlain, Alam, Mohammad Sarwar, Hamid, Hinna, Dhulap, Abhijeet, Umar, Sadiq, Yar, Mohammad Shahar, Bano, Sameena, Nazreen, Syed, Ali, Yakub, Kharbanda, Chetna

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 2.57 MB

english, 2014

25

Synthesis and pharmacological evaluation of someN3-aryl/heteroaryl-substituted 2-(2-chlorostyryl)-6,7-dimethoxy-quinazolin-4(3H)-ones as potential anticonvulsant agents

Das, Nirupam, Garabadu, Debapriya, Banerjee, Anupam G., Krishnamurthy, Sairam, Shrivastava, Sushant K.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 595 KB

english, 2014

26

Synthesis and in vitro antiproliferative evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones

Ríos, David, Benites, Julio, Torrejón, Felipe, Theoduloz, Cristina, Valderrama, Jaime A.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 344 KB

english, 2014

27

Synthesis, central nervous system activity, and structure–activity relationship of 1-aryl-6-benzyl-7-hydroxy-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-ones

Rządkowska, Marzena, Szacoń, Elżbieta, Kaczor, Agnieszka A., Fidecka, Sylwia, Kędzierska, Ewa, Matosiuk, Dariusz

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

28

1,4-Diaryl-2-mercaptoimidazoles derivatives as a novel class of antimicrobial agents: design, synthesis, and computational studies

Gupta, Girish Kumar, Saini, Vipin, Khare, Rajshree, Kumar, Vinod

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 910 KB

english, 2014

29

QSAR and pharmacophore modeling of diverse aminothiazoles and aminopyridines for antimalarial potency against multidrug-resistantPlasmodium falciparum

Aher, Rahul Balasaheb, Roy, Kunal

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 2.43 MB

english, 2014

30

Design and synthesis of novel heterocyclic acetamide derivatives for potential analgesic, anti-inflammatory, and antimicrobial activities

Nayak, Prakash S., Narayana, B., Sarojini, B. K., Hegde, Karunakara, Shashidhara, K. S.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014