Volume 25; Issue 9

Medicinal Chemistry Research

Volume 25; Issue 9

1

Synthesis, spectroscopic characterization, X-ray structure, and in vivo neurotropic activity of new 1,5-benzodiazepin-2-ones

Gaponov, Alexandr A., Zlenko, Elena T., Shishkina, Svetlana V., Shishkin, Oleg V., Antypenko, Oleksii M., Tretiakov, Serhii V., Palchikov, Vitaliy A.

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 598 KB

english, 2016

2

2,4-Disubstituted thiazoles as multitargated bioactive molecules

Arora, Preeti, Narang, Rakesh, Nayak, Surendra Kumar, Singh, Sachin Kumar, Judge, Vikramjeet

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 2.71 MB

english, 2016

3

Ferrocenyl chalcones withO-alkylated vanillins: synthesis, spectral characterization, microbiological evaluation, and single-crystal X-ray analysis

Muškinja, Jovana, Burmudžija, Adrijana, Ratković, Zoran, Ranković, Branislav, Kosanić, Marijana, Bogdanović, Goran A., Novaković, Slađana B.

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

4

Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation

Sudha, Arumugam, Jeyakanthan, Jeyaraman, Srinivasan, Pappu

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 811 KB

english, 2016

5

Synthesis, characterization and biological evaluation of 7-substituted- 4-((1-aryl-1H-1,2,3-triazol-4-yl) methyl)-2H-benzo[b][1,4]oxazin- 3(4H)-ones as anticancer agents

Nagavelli, Vasudeva Reddy, Nukala, Satheesh Kumar, Narsimha, Sirassu, Battula, Kumara Swamy, Tangeda, Savitha Jyostna, Reddy, Yellu Narasimha

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 766 KB

english, 2016

6

Synthesis and biological evaluation of some functionalized 1H-1,2,3-triazole tethered pyrazolo[3,4-b]pyridin-6(7H)-ones as antimicrobial and apoptosis inducing agents

Sindhu, Jayant, Singh, Harjinder, Khurana, J. M., Bhardwaj, Jitender Kumar, Saraf, Priyanka, Sharma, Chetan

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

7

Hetero-annulated coumarins as new AChE/BuChE inhibitors: synthesis and biological evaluation

Ebrahimi, Seyed Esmaeil Sadat, Ghadirian, Pegah, Emtiazi, Hamideh, Yahya-Meymandi, Azadeh, Saeedi, Mina, Mahdavi, Mohammad, Nadri, Hamid, Moradi, Alireza, Sameem, Bilqees, Vosooghi, Mohsen, Emami, Sae

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 450 KB

english, 2016

8

Synthesis, characterization, antimicrobial activity, and QSAR studies on substituted oxadiazaboroles

Pir, Meryem, Agirbas, Hikmet, Budak, Fatma, Ilter, Merve

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 552 KB

english, 2016

9

Synthesis and antiproliferative studies of curcumin pyrazole derivatives

Puneeth, Honnalagere Ramesh, Ananda, Hanumappa, Kumar, Kothanahally S. Sharath, Rangappa, Kanchugarakoppal S., Sharada, Angatahally Chandrashekariah

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 990 KB

english, 2016

10

Synthesis, in vitro potential and computational studies on 2-amino-1, 4-dihydropyrimidines as multitarget antibacterial ligands

Ahmad, Muhammad Jawad, Hassan, Syed Fahad, Nisa, Riffat Un, Ayub, Khurshid, Nadeem, Muhammad Shahid, Nazir, Samina, Ansari, Farzana Latif, Qureshi, Naveeda Akhtar, Rashid, Umer

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1004 KB

english, 2016

11

Synthesis, spectral characterization, and effective antifungal evaluation of 1H-tetrazole containing 1,3,5-triazine dendrimers

Vembu, Sandhirakasu, Pazhamalai, Srinivasan, Gopalakrishnan, Mannathusamy

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 608 KB

english, 2016

12

Novel quinolone-3-carboxylic acid derivatives as anti-HIV-1 agents: design, synthesis, and biological activities

Hajimahdi, Z., Zabihollahi, R., Aghasadeghi, M. R., Ashtiani, S. Hosseini, Zarghi, A.

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 786 KB

english, 2016

13

QSAR model development for studying carbonic anhydrase inhibitors as anticonvulsant agents

Ajeet,, Mishra, Arun K., Kumar, Arvind

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 587 KB

english, 2016

14

Identifying potential PPARγ agonist/partial agonist from plant molecules to control type 2 diabetes using in silico and in vivo models

Stalin, Antony, Stephen Irudayaraj, Santiagu, Ramesh Kumar, Dhandapani, Balakrishna, Kedike, Ignacimuthu, Savarimuthu, Al-Dhabi, Naif Abdullah, Duraipandiyan, Veeramuthu

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 8.38 MB

english, 2016

15

Synthesis of novel 1,2,3-triazole tethered 1,3-disubstitutedβ-carboline derivatives and their cytotoxic and antibacterial activities

Salehi, Peyman, Babanezhad-Harikandei, Kosar, Bararjanian, Morteza, Al-Harrasi, Ahmed, Esmaeili, Mohammad-Ali, Aliahmadi, Atousa

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 618 KB

english, 2016

16

1H-benzimidazole derivatives as butyrylcholinesterase inhibitors: synthesis and molecular modeling studies

Coban, Gunes, Carlino, Luca, Tarikogullari, Ayse Hande, Parlar, Sülünay, Sarıkaya, Görkem, Alptüzün, Vildan, Alpan, Ayşe Selcen, Güneş, Hasan Semih, Erciyas, Erçin

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

17

Syntheses, in vitro evaluation and molecular docking studies of 5-bromo-2-aryl benzimidazoles asα-glucosidase inhibitors

Arshad, Tanzila, Khan, Khalid Mohammed, Rasool, Najma, Salar, Uzma, Hussain, Shafqat, Tahir, Tehreem, Ashraf, Mohammed, Wadood, Abdul, Riaz, Muhammad, Perveen, Shahnaz, Taha, Muhammad, Ismail, Nor Had

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

18

Mercuric chloride catalyzed synthesis of some anticancer 2-aryl-2,3-dihydroquinizolin-4(1H)-ones

Ramesh, Navudu, Rao, Mannem Gangadhara, Varala, Ravi, Rao, V. Umamaheswra, Babu, B. Hari

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1010 KB

english, 2016

19

Synthesis and biological evaluation of new Mannich and Schiff bases containing 1,2,4-triazole and 1,3,4-oxadiazole nucleus

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 613 KB

english, 2016

20

Anticancer activity of some [1,2,4]triazepino[2,3-a] quinazoline derivatives: monolayer and multicellular spheroids in vitro models

Awad, Hanem M., Fayad, Walid, El-Hallouty, Salwa M., Farghaly, Thoraya A., Abdallah, Mohamad M.

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 343 KB

english, 2016

21

Design and synthesis of ring C opened analogues ofα-santonin as potential anticancer agents

Khazir, Jabeena, Mir, Bilal Ahmad, Pilcher, Lynne A., Riley, Darren L., Chashoo, Gousia, Islam, Md. Ataul, Saxena, Ajit K., Kumar, H. M. Sampath

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

22

Synthesis, antimalarial activity evaluation and docking studies of some novel tetraoxaquines

Kumawat, Mukesh Kumar, Parida, Pratap, Chetia, Dipak

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

23

Antiproliferative and antioxidative effects of novel hydrazone derivatives bearing coumarin and chromene moiety

Angelova, Violina T., Vassilev, Nikolay G., Nikolova-Mladenova, Boryana, Vitas, Jasmina, Malbaša, Radomir, Momekov, Georgi, Djukic, Mirjana, Saso, Luciano

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 813 KB

english, 2016

24

Study of solvent effects on structural and conformational properties of cimetidine tautomers

Taherpour, Avat, Rahimizadeh, Razieh

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 4.62 MB

english, 2016

25

Synthesis and evaluation of antiproliferative activity of novel quinazolin-4(3H)-one derivatives

Venkatesh, Ramineni, Kasaboina, Suresh, Janardhan, Sridhara, Jain, Nishant, Bantu, Rajashaker, Nagarapu, Lingaiah

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.70 MB

english, 2016

26

Synthesis, characterization, drug-likeness properties and determination of the in vitro antioxidant and cytotoxic activities of new 1,3,4-oxadiazole derivatives

Nazarbahjat, Nafal, Ariffin, Azhar, Abdullah, Zanariah, Abdulla, Mahmood Ameen, Shia, John Kwong Siew, Leong, Kok Hoong

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

27

Membrane proteome functional characterization of breast cancer-initiating cells subjected to bone morphogenetic protein signaling inhibition by dorsomorphin

Piovesana, Susy, Capriotti, Anna Laura, Colapicchioni, Valentina, Ferraris, Francesca, La Barbera, Giorgia, Ventura, Salvatore

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

28

Cytotoxic and anticancer activities of an acridine derivative; 11-chloro-3-methyl-3H-imidazo[4,5-a]acridine on 5637 cells

Hassanzadeh, Halimeh, Bahrami, Ahmad Reza, Sadeghian, Hamid, Rahimizadeh, Mohammad, Matin, Maryam M.

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 483 KB

english, 2016

29

Asiatic acid, a non-detergent type spermicide: exploration of plausible pathway of spermicidal action

Kumar, Shrabanti, Bharitkar, Yogesh P., Kumar, Gopinatha S., Mondal, Nirup B.

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

30

ECV304/C6 coculture model of the BBB coupled with LC–MS analysis for drug screening from Rhubarb extract

Yuan, Jiang-Feng, Ji, Hui-Hui, Qiu, Zhi-Jun, Wang, Da-Hong

Journal:

Medicinal Chemistry Research

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

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