Volume 10; Issue 6

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ACS Chemical Biology
Volume 10; Issue 6

ACS Chemical Biology

Volume 10; Issue 6

1

A New Class of Orthosteric uPAR·uPA Small-Molecule Antagonists Are Allosteric Inhibitors of the uPAR·Vitronectin Interaction

Liu, Degang, Zhou, Donghui, Wang, Bo, Knabe, William Eric, Meroueh, Samy O.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.94 MB

english, 2015

2

Enantiomers of 3-Methylspermidine Selectively Modulate Deoxyhypusine Synthesis and Reveal Important Determinants for Spermidine Transport

Hyvönen, Mervi T., Khomutov, Maxim, Petit, Marine, Weisell, Janne, Kochetkov, Sergey N., Alhonen, Leena, Vepsäläinen, Jouko, Khomutov, Alex R., Keinänen, Tuomo A.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

3

N -Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

Fang, Wenxia, Robinson, David A., Raimi, Olawale G., Blair, David E., Harrison, Justin R., Lockhart, Deborah E. A., Torrie, Leah S., Ruda, Gian Filippo, Wyatt, Paul G., Gilbert, Ian H., van Aalten, Da

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.98 MB

english, 2015

4

Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction

Wu, Xiaoqing, Lan, Lan, Wilson, David Michael, Marquez, Rebecca T., Tsao, Wei-chung, Gao, Philip, Roy, Anuradha, Turner, Benjamin Andrew, McDonald, Peter, Tunge, Jon A, Rogers, Steven A, Dixon, Dan A.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 4.08 MB

english, 2015

5

Discovery of Novel Pneumococcal Surface Antigen A (PsaA) Inhibitors Using a Fragment-based Drug Design Approach

Bajaj, Megha, Mamidyala, Sreeman K., Zuegg, Johannes, Begg, Stephanie L., Ween, Miranda P., Luo, Zhenyao, Huang, Johnny X., McEwan, Alastair G., Kobe, Bostjan, Paton, James C., McDevitt, Christopher A

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.22 MB

english, 2015

6

Exquisitely Specific Bisubstrate Inhibitors of c-Src Kinase

Brandvold, Kristoffer R., Santos, Shana M., Breen, Meghan E., Lachacz, Eric J., Steffey, Michael E., Soellner, Matthew B.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 708 KB

english, 2015

7

Chemoenzymatically Prepared Heparan Sulfate Containing Rare 2-O-Sulfonated Glucuronic Acid Residues

Boothello, Rio S., Sarkar, Aurijit, Tran, Vy My, Nguyen, Thao Kim Nu, Sankaranarayanan, Nehru Viji, Mehta, Akul Y., Alabbas, AlHumaidi, Brown, Spencer, Rossi, Alessandro, Joice, April C., Mencio, Cait

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

8

A Small Molecule That Inhibits OGT Activity in Cells

Ortiz-Meoz, Rodrigo F., Jiang, Jiaoyang, Lazarus, Michael B., Orman, Marina, Janetzko, John, Fan, Chenguang, Duveau, Damien Y., Tan, Zhi-Wei, Thomas, Craig J., Walker, Suzanne

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

9

Constructing de Novo H 2 O 2 Signaling via Induced Protein Proximity

Zeng, Guihua, Zhang, Roushu, Xuan, Weimin, Wang, Wei, Liang, Fu-Sen

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.03 MB

english, 2015

10

A Simple Method for GFP- and RFP-based Dual Color Single-Molecule Localization Microscopy

Platonova, Evgenia, Winterflood, Christian M., Ewers, Helge

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 946 KB

english, 2015

11

Inhibitor Recognition Specificity of MERS-CoV Papain-like Protease May Differ from That of SARS-CoV

Lee, Hyun, Lei, Hao, Santarsiero, Bernard D., Gatuz, Joseph L., Cao, Shuyi, Rice, Amy J., Patel, Kavankumar, Szypulinski, Michael Z., Ojeda, Isabel, Ghosh, Arun K., Johnson, Michael E.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 5.61 MB

english, 2015

12

Starter Unit Flexibility for Engineered Product Synthesis by the Nonreducing Polyketide Synthase PksA

Huitt-Roehl, Callie R., Hill, Eric A., Adams, Martina M., Vagstad, Anna L., Li, Jesse W., Townsend, Craig A.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.63 MB

english, 2015

13

Hydrocarbon Stapled Peptides as Modulators of Biological Function

Cromm, Philipp M., Spiegel, Jochen, Grossmann, Tom N.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 5.43 MB

english, 2015

14

Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation

Albright, Jessica C., Henke, Matthew T., Soukup, Alexandra A., McClure, Ryan A., Thomson, Regan J., Keller, Nancy P., Kelleher, Neil L.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

15

Molecular Tweezers Inhibit Islet Amyloid Polypeptide Assembly and Toxicity by a New Mechanism

Lopes, Dahabada H. J., Attar, Aida, Nair, Gayatri, Hayden, Eric Y., Du, Zhenming, McDaniel, Kirsten, Dutt, Som, Bandmann, Heinz, Bravo-Rodriguez, Kenny, Mittal, Sumit, Klärner, Frank-Gerrit, Wang, Chu

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.06 MB

english, 2015

16

Diazirine Photocrosslinking Recruits Activated FTO Demethylase Complexes for Specific N 6 -methyladenosine Recognition

Jeong, Hyun Seok, Hayashi, Gosuke, Okamoto, Akimitsu

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 2.39 MB

english, 2015

17

Covalent Molecular Probes for Class A G Protein-Coupled Receptors: Advances and Applications

Weichert, Dietmar, Gmeiner, Peter

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

18

Observing Lysozyme’s Closing and Opening Motions by High-Resolution Single-Molecule Enzymology

Akhterov, Maxim V., Choi, Yongki, Olsen, Tivoli J., Sims, Patrick C., Iftikhar, Mariam, Gul, O. Tolga, Corso, Brad L., Weiss, Gregory A., Collins, Philip G.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

19

Solvatochromic Nile Red Probes with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

Kreder, Rémy, Pyrshev, Kyrylo A., Darwich, Zeinab, Kucherak, Oleksandr A., Mély, Yves, Klymchenko, Andrey S.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

20

Optochemical Dissection of T-box Gene-Dependent Medial Floor Plate Development

Payumo, Alexander Y., Walker, Whitney J., McQuade, Lindsey E., Yamazoe, Sayumi, Chen, James K.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 7.63 MB

english, 2015

21

Chemical Biology of Nucleic Acids

Barciszewski, Jan, Marquez, Victor E., Vasseur, Jean-Jacques, Markiewicz, Wojciech T.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 399 KB

english, 2015

22

Rutaecarpine Analogues Reduce Lipid Accumulation in Adipocytes via Inhibiting Adipogenesis/Lipogenesis with AMPK Activation and UPR Suppression

Chen, Ying-Chun, Zeng, Xiao-Yi, He, Yan, Liu, Hong, Wang, Bin, Zhou, Han, Chen, Jian-Wen, Liu, Pei-Qing, Gu, Lian-Quan, Ye, Ji-Ming, Huang, Zhi-Shu

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 471 KB

english, 2015

23

PKA-Type I Selective Constrained Peptide Disruptors of AKAP Complexes

Wang, Yuxiao, Ho, Tienhuei G., Franz, Eugen, Hermann, Jennifer S., Smith, F. Donelson, Hehnly, Heidi, Esseltine, Jessica L., Hanold, Laura E., Murph, Mandi M., Bertinetti, Daniela, Scott, John D., Her

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 3.22 MB

english, 2015

24

Orthogonal Thiol Functionalization at a Single Atomic Center for Profiling Transthiolation Activity of E1 Activating Enzymes

Stanley, Mathew, Han, Cong, Knebel, Axel, Murphy, Paul, Shpiro, Natalia, Virdee, Satpal

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 6.38 MB

english, 2015

25

A Nonapoptotic Role for BAX and BAK in Eicosanoid Metabolism

Zhang, Tejia, Walensky, Loren D., Saghatelian, Alan

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

26

Introducing Our Authors

Powell, Rachelle

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 803 KB

english, 2015

27

In This Issue

Underwood, Jason G.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

28

Spotlights

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

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