Volume 7; Issue 5

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ACS Chemical Biology
Volume 7; Issue 5

ACS Chemical Biology

Volume 7; Issue 5

1

Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor

Puskar, Nyssa L., Lester, Henry A., Dougherty, Dennis A.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 268 KB

english, 2012

2

Redesign of Glycopeptide Antibiotics: Back to the Future

James, Robert C., Pierce, Joshua G., Okano, Akinori, Xie, Jian, Boger, Dale L.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

3

Glycan Fingerprints: Calculating Diversity in Glycan Libraries

Rademacher, Christoph, Paulson, James C.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 1.61 MB

english, 2012

4

The Three Cornerstones of Chemical Biology: Innovative Probes, New Discoveries, and Enabling Tools

Thompson, Andrea D., Makley, Leah N., McMenimen, Kathryn, Gestwicki, Jason E.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.86 MB

english, 2012

5

Small-Molecule Inhibitors of Bacterial AddAB and RecBCD Helicase-Nuclease DNA Repair Enzymes

Amundsen, Susan K., Spicer, Timothy, Karabulut, Ahmet C., Londoño, Luz Marina, Eberhart, Christina, Fernandez Vega, Virneliz, Bannister, Thomas D., Hodder, Peter, Smith, Gerald R.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 4.39 MB

english, 2012

6

Role of Pseudouridine in Structural Rearrangements of Helix 69 During Bacterial Ribosome Assembly

Sakakibara, Yogo, Chow, Christine S.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

7

Celastrol Analogues as Inducers of the Heat Shock Response. Design and Synthesis of Affinity Probes for the Identification of Protein Targets

Klaić, Lada, Morimoto, Richard I., Silverman, Richard B.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.95 MB

english, 2012

8

The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508

Baumli, Sonja, Hole, Alison J., Noble, Martin E. M., Endicott, Jane A.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.89 MB

english, 2012

9

Visualization and Quantitative Analysis of G Protein-Coupled Receptor−β-Arrestin Interaction in Single Cells and Specific Organs of Living Mice Using Split Luciferase Complementation

Takakura, Hideo, Hattori, Mitsuru, Takeuchi, Masaki, Ozawa, Takeaki

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 3.60 MB

english, 2012

10

Bicyclic Peptide Inhibitor Reveals Large Contact Interface with a Protease Target

Angelini, Alessandro, Cendron, Laura, Chen, Shiyu, Touati, Jeremy, Winter, Greg, Zanotti, Giuseppe, Heinis, Christian

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.96 MB

english, 2012

11

Amide Analogues of CD1d Agonists Modulate i NKT-Cell-Mediated Cytokine Production

Wojno, Justyna, Jukes, John-Paul, Ghadbane, Hemza, Shepherd, Dawn, Besra, Gurdyal S., Cerundolo, Vincenzo, Cox, Liam R.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.34 MB

english, 2012

12

In This Issue

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 760 KB

english, 2012

13

A High-Throughput Screen for the Engineered Production of β-Lactam Antibiotics

Phelan, Ryan M., DiPardo, Benjamin J., Townsend, Craig A.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

14

Sulfolipid-1 Biosynthesis Restricts Mycobacterium tuberculosis Growth in Human Macrophages

Gilmore, Sarah A., Schelle, Michael W., Holsclaw, Cynthia M., Leigh, Clifton D., Jain, Madhulika, Cox, Jeffery S., Leary, Julie A., Bertozzi, Carolyn R.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 756 KB

english, 2012

15

Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein

Sasazawa, Yukiko, Kanagaki, Shuhei, Tashiro, Etsu, Nogawa, Toshihiko, Muroi, Makoto, Kondoh, Yasumitsu, Osada, Hiroyuki, Imoto, Masaya

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.53 MB

english, 2012

16

A Chemical Screen Identifies Class A G-Protein Coupled Receptors As Regulators of Cilia

Avasthi, Prachee, Marley, Aaron, Lin, Henry, Gregori-Puigjane, Elisabet, Shoichet, Brian K., von Zastrow, Mark, Marshall, Wallace F.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.75 MB

english, 2012

17

A Win for Bioorthogonal Chemistry

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 127 KB

english, 2012

18

Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification

Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Scharow, Andrej, Berg, Thorsten, Yaffe, Michael B., Lee, Kyung S., Burke, Terrence R.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 4.59 MB

english, 2012

19

Introducing Our Authors

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 4.38 MB

english, 2012

20

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery

Mills, Stephen J., Persson, Camilla, Cozier, Gyles, Thomas, Mark P., Trésaugues, Lionel, Erneux, Christophe, Riley, Andrew M., Nordlund, Pär, Potter, Barry V. L.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.88 MB

english, 2012

21

Spotlight

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

22

Rationally Designed Small Molecules Targeting the RNA That Causes Myotonic Dystrophy Type 1 Are Potently Bioactive

Childs-Disney, Jessica L., Hoskins, Jason, Rzuczek, Suzanne G., Thornton, Charles A., Disney, Matthew D.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.58 MB

english, 2012

23

Allosteric Tertiary Interactions Preorganize the c-di-GMP Riboswitch and Accelerate Ligand Binding

Wood, Sharla, Ferré-D’Amaré, Adrian R., Rueda, David

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.27 MB

english, 2012