Volume 8; Issue 5

Main
ACS Chemical Biology
Volume 8; Issue 5

ACS Chemical Biology

Volume 8; Issue 5

1

RNA “Traffic Lights”: An Analytical Tool to Monitor siRNA Integrity

Holzhauser, Carolin, Liebl, Renate, Goepferich, Achim, Wagenknecht, Hans-Achim, Breunig, Miriam

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.31 MB

english, 2013

2

Aestuaramides, a Natural Library of Cyanobactin Cyclic Peptides Resulting from Isoprene-Derived Claisen Rearrangements

McIntosh, John A., Lin, Zhenjian, Tianero, Ma. Diarey B., Schmidt, Eric W.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.40 MB

english, 2013

3

Evidence for Context-Dependent Complementarity of Non-Shine-Dalgarno Ribosome Binding Sites to Escherichia coli rRNA

Barendt, Pamela A., Shah, Najaf A., Barendt, Gregory A., Kothari, Parth A., Sarkar, Casim A.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

4

A Molecular-Beacon-Based Screen for Small Molecule Inhibitors of miRNA Maturation

Bose, Debojit, Jayaraj, Gopal Gunanathan, Kumar, Santosh, Maiti, Souvik

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 437 KB

english, 2013

5

Chemical Perturbation of Mcl-1 Pre-mRNA Splicing to Induce Apoptosis in Cancer Cells

Gao, Yang, Koide, Kazunori

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 401 KB

english, 2013

6

Discovery of the Antibiotic Phosacetamycin via a New Mass Spectrometry-Based Method for Phosphonic Acid Detection

Evans, Bradley S., Zhao, Changming, Gao, Jiangtao, Evans, Courtney M., Ju, Kou-San, Doroghazi, James R., van der Donk, Wilfred A., Kelleher, Neil L., Metcalf, William W.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 383 KB

english, 2013

7

Conformation Guides Molecular Efficacy in Docking Screens of Activated β-2 Adrenergic G Protein Coupled Receptor

Weiss, Dahlia R., Ahn, SeungKirl, Sassano, Maria F., Kleist, Andrew, Zhu, Xiao, Strachan, Ryan, Roth, Bryan L., Lefkowitz, Robert J., Shoichet, Brian K.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 4.62 MB

english, 2013

8

Untangling Amyloid-β, Tau, and Metals in Alzheimer’s Disease

Savelieff, Masha G., Lee, Sanghyun, Liu, Yuzhong, Lim, Mi Hee

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.58 MB

english, 2013

9

Phenotypic Screening with Oleaginous Microalgae Reveals Modulators of Lipid Productivity

Franz, Annaliese K., Danielewicz, Megan A., Wong, Diana M., Anderson, Lisa A., Boothe, Jordan R.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.85 MB

english, 2013

10

Novel Inhibitor Binding Site Discovery on HIV-1 Capsid N-Terminal Domain by NMR and X-ray Crystallography

Goudreau, Nathalie, Lemke, Christopher T., Faucher, Anne-Marie, Grand-Maître, Chantal, Goulet, Sylvie, Lacoste, Jean-Eric, Rancourt, Jean, Malenfant, Eric, Mercier, Jean-François, Titolo, Steve, Mason

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.07 MB

english, 2013

11

Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death

Adams, Drew J., Boskovic, Zarko V., Theriault, Jimmy R., Wang, Alex J., Stern, Andrew M., Wagner, Bridget K., Shamji, Alykhan F., Schreiber, Stuart L.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 409 KB

english, 2013

12

A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice

Godinat, Aurélien, Park, Hyo Min, Miller, Stephen C., Cheng, Ke, Hanahan, Douglas, Sanman, Laura E., Bogyo, Matthew, Yu, Allen, Nikitin, Gennady F., Stahl, Andreas, Dubikovskaya, Elena A.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 3.15 MB

english, 2013

13

First Structure of Protein Kinase CK2 Catalytic Subunit with an Effective CK2β-Competitive Ligand

Raaf, Jennifer, Guerra, Barbara, Neundorf, Ines, Bopp, Bertan, Issinger, Olaf-Georg, Jose, Joachim, Pietsch, Markus, Niefind, Karsten

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 3.39 MB

english, 2013

14

De Novo Design of Protein Kinase Inhibitors by in Silico Identification of Hinge Region-Binding Fragments

Urich, Robert, Wishart, Grant, Kiczun, Michael, Richters, André, Tidten-Luksch, Naomi, Rauh, Daniel, Sherborne, Brad, Wyatt, Paul G., Brenk, Ruth

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 3.18 MB

english, 2013

15

Structure of Mycobacterial β-Oxidation Trifunctional Enzyme Reveals Its Altered Assembly and Putative Substrate Channeling Pathway

Venkatesan, Rajaram, Wierenga, Rik K.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

16

Substrate-Specific Conformational Regulation of the Receptor Tyrosine Kinase VEGFR2 Catalytic Domain

Solowiej, James, Chen, Jeffrey H., Zou, Helen Y., Grant, Stephan K., Murray, Brion W.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 739 KB

english, 2013

17

Antibody-Mimetic Ligand Selected by mRNA Display Targets DC-SIGN for Dendritic Cell-Directed Antigen Delivery

Xiao, Liang, Hung, Kuo-Chan, Takahashi, Terry T., Joo, Kye-Il, Lim, Matthew, Roberts, Richard W., Wang, Pin

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 4.87 MB

english, 2013

18

Dimerized Glycosaminoglycan Chains Increase FGF Signaling during Zebrafish Development

Nguyen, Thao K. N., Tran, Vy M., Sorna, Venkataswamy, Eriksson, Inger, Kojima, Akinori, Koketsu, Mamoru, Loganathan, Duraikkannu, Kjellén, Lena, Dorsky, Richard I., Chien, Chi-Bin, Kuberan, Balaguruna

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

19

Eupalinilide E Inhibits Erythropoiesis and Promotes the Expansion of Hematopoietic Progenitor Cells

de Lichtervelde, Lorenzo, Boitano, Anthony E., Wang, Ying, Krastel, Philipp, Petersen, Frank, Cooke, Michael P., Schultz, Peter G.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

20

Small Molecule Screen Reveals Regulation of Survival Motor Neuron Protein Abundance by Ras Proteins

Letso, Reka R., Bauer, Andras J., Lunn, Mitchell R., Yang, Wan Seok, Stockwell, Brent R.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1002 KB

english, 2013

21

Reporter Enzyme Inhibitor Study To Aid Assembly of Orthogonal Reporter Gene Assays

Ho, Pei-i, Yue, Kimberley, Pandey, Pramod, Breault, Lyne, Harbinski, Fred, McBride, Aaron J., Webb, Brian, Narahari, Janaki, Karassina, Natasha, Wood, Keith V., Hill, Adam, Auld, Douglas S.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 3.01 MB

english, 2013

22

Chimera of IL-2 Linked to Light Chain of anti-IL-2 mAb Mimics IL-2/anti-IL-2 mAb Complexes Both Structurally and Functionally

Tomala, Jakub, Kovarova, Jirina, Kabesova, Martina, Votavova, Petra, Chmelova, Helena, Dvorakova, Barbora, Rihova, Blanka, Kovar, Marek

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 882 KB

english, 2013

23

A Novel CUG exp ·MBNL1 Inhibitor with Therapeutic Potential for Myotonic Dystrophy Type 1

Jahromi, Amin Haghighat, Nguyen, Lien, Fu, Yuan, Miller, Kali A., Baranger, Anne M., Zimmerman, Steven C.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.59 MB

english, 2013

24

Chemical Interrogation of the Neuronal Kinome Using a Primary Cell-Based Screening Assay

Al-Ali, Hassan, Schürer, Stephan C., Lemmon, Vance P., Bixby, John L.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 3.75 MB

english, 2013

25

Chaperones Rejuvenate Folding and Activity of 3-β Hydroxysteroid Dehydrogenase 2

Rajapaksha, Maheshinie, Prasad, Manoj, Thomas, James L., Whittal, Randy M., Bose, Himangshu S.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

26

Synthesis and Assessment of Glycosaminoglycan Priming Activity of Cluster-xylosides for Potential Use as Proteoglycan Mimetics

Tran, Vy M., Nguyen, Thao K. N., Sorna, Venkataswamy, Loganathan, Duraikkannu, Kuberan, Balagurunathan

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.01 MB

english, 2013

27

Correction to Revealing Nature’s Synthetic Potential through the Study of Ribosomal Natural Product Biosynthesis

Dunbar, Kyle L., Mitchell, Douglas A.

Journal:

ACS Chemical Biology

Year:

2013

File:

PDF, 105 KB

2013

28

In This Issue

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 675 KB

english, 2013

29

Glaziovianin A Prevents Endosome Maturation via Inhibiting Microtubule Dynamics

Chinen, Takumi, Kazami, Sayaka, Nagumo, Yoko, Hayakawa, Ichiro, Ikedo, Akiyuki, Takagi, Masatoshi, Yokosuka, Akihito, Imamoto, Naoko, Mimaki, Yoshihiro, Kigoshi, Hideo, Osada, Hiroyuki, Usui, Takeo

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 4.36 MB

english, 2013

30

Spotlight

Gordon, Eva J., Webb, Sarah A., Underwood, Jason G.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 774 KB

english, 2013

31

Introducing Our Authors

Powell, Rachelle

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 650 KB

english, 2013