Volume 9; Issue 12

Main
ACS Chemical Biology
Volume 9; Issue 12

ACS Chemical Biology

Volume 9; Issue 12

1

Recent Progress in Design of Protein-Based Fluorescent Biosensors and Their Cellular Applications

Tamura, Tomonori, Hamachi, Itaru

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

2

Direct Binding of Bcl-2 Family Proteins by Quercetin Triggers Its Pro-Apoptotic Activity

Primikyri, Alexandra, Chatziathanasiadou, Maria V., Karali, Evdoxia, Kostaras, Eleftherios, Mantzaris, Michalis D., Hatzimichael, Eleftheria, Shin, Jae-Sun, Chi, Seung-Wook, Briasoulis, Evangelos, Kol

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

3

Evolved Sequence Contexts for Highly Efficient Amber Suppression with Noncanonical Amino Acids

Pott, Moritz, Schmidt, Moritz Johannes, Summerer, Daniel

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 643 KB

english, 2014

4

Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates

Duim, Whitney C., Jiang, Yan, Shen, Koning, Frydman, Judith, Moerner, W. E.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 6.60 MB

english, 2014

5

Reconstruction of Cladoniamide Biosynthesis Reveals Nonenzymatic Routes to Bisindole Diversity

Du, Yi-Ling, Williams, David E., Patrick, Brian O., Andersen, Raymond J., Ryan, Katherine S.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 780 KB

english, 2014

6

Bypassing Fluoroquinolone Resistance with Quinazolinediones: Studies of Drug–Gyrase–DNA Complexes Having Implications for Drug Design

Drlica, Karl, Mustaev, Arkady, Towle, Tyrell R., Luan, Gan, Kerns, Robert J., Berger, James M.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

7

Identification of a Small Molecule That Turns ON the Pluripotency Gene Circuitry in Human Fibroblasts

Pandian, Ganesh N., Sato, Shinsuke, Anandhakumar, Chandran, Taniguchi, Junichi, Takashima, Kazuhiro, Syed, Junetha, Han, Le, Saha, Abhijit, Bando, Toshikazu, Nagase, Hiroki, Sugiyama, Hiroshi

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.58 MB

english, 2014

8

Biological Matching of Chemical Reactivity: Pairing Indole Nucleophilicity with Electrophilic Isoprenoids

Walsh, Christopher T.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

9

Lipid-Dependent Bimodal MCL1 Membrane Activity

Landeta, Olatz, Valero, Juan Garcia, Flores-Romero, Hector, Bustillo-Zabalbeitia, Itsasne, Landajuela, Ane, Garcia-Porras, Miguel, Terrones, Oihana, Basañez, Gorka

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 7.32 MB

english, 2014

10

MitoBlue: A Nontoxic and Photostable Blue-Emitting Dye That Selectively Labels Functional Mitochondria

Sánchez, Mateo I., Martínez-Costas, José, Mascareñas, José L., Vázquez, M. Eugenio

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.95 MB

english, 2014

11

Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo PHD Finger

Miller, Thomas C. R., Rutherford, Trevor J., Birchall, Kristian, Chugh, Jasveen, Fiedler, Marc, Bienz, Mariann

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.92 MB

english, 2014

12

Sulfhydryl-Specific Probe for Monitoring Protein Redox Sensitivity

Lee, Jae-Jin, Ha, Sura, Kim, Hee-Jung, Ha, Hyun Joo, Lee, Hee-Yoon, Lee, Kong-Joo

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 5.24 MB

english, 2014

13

Interfacing Chemical Biology and Drug Discovery: Report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2–4, 2014, Rouen, France

Sapi, Janos, Schmidt, Frédéric, Van Hijfte, Luc, George, Pascal

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

14

Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor

Lamberto, Ilaria, Lechtenberg, Bernhard C., Olson, Erika J., Mace, Peter D., Dawson, Philip E., Riedl, Stefan J., Pasquale, Elena B.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.07 MB

english, 2014

15

Inhibition of the Ferric Uptake Regulator by Peptides Derived from Anti-FUR Peptide Aptamers: Coupled Theoretical and Experimental Approaches

Cissé, Cheickna, Mathieu, Sophie V., Abeih, Mohamed B. Ould, Flanagan, Lindsey, Vitale, Sylvia, Catty, Patrice, Boturyn, Didier, Michaud-Soret, Isabelle, Crouzy, Serge

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 343 KB

english, 2014

16

Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis

Yachnin, Brahm J., McEvoy, Michelle B., MacCuish, Roderick J. D., Morley, Krista L., Lau, Peter C. K., Berghuis, Albert M.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

17

O 6 -Alkylguanine Postlesion DNA Synthesis Is Correct with the Right Complement of Hydrogen Bonding

Gahlon, Hailey L., Boby, Melissa L., Sturla, Shana J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 6.62 MB

english, 2014

18

Introducing Our Authors

Powell, Rachelle

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.61 MB

english, 2014

19

Phosphatase-Inert Glucosamine 6-Phosphate Mimics Serve as Actuators of the glmS Riboswitch

Fei, Xiang, Holmes, Thomas, Diddle, Julianna, Hintz, Lauren, Delaney, Dan, Stock, Alex, Renner, Danielle, McDevitt, Molly, Berkowitz, David B., Soukup, Juliane K.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.72 MB

english, 2014

20

Fluorinated Aromatic Amino Acids Are Sensitive 19 F NMR Probes for Bromodomain-Ligand Interactions

Mishra, Neeraj K., Urick, Andrew K., Ember, Stuart W. J., Schönbrunn, Ernst, Pomerantz, William C.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.93 MB

english, 2014

21

Spotlights

Dahlmann, Heidi A., Underwood, Jason G., Soares, Jitesh A.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.63 MB

english, 2014

22

Chemical Genetics Screening Reveals KIAA1363 as a Cytokine-Lowering Target

Hunerdosse, Devon M., Morris, Patrick J., Miyamoto, David K., Fisher, Karl J., Bateman, Leslie A., Ghazaleh, Jonathan R., Zhong, Sharon, Nomura, Daniel K.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.90 MB

english, 2014

23

In This Issue

Underwood, Jason

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1008 KB

english, 2014

24

Polyketide Intermediate Mimics as Probes for Revealing Cryptic Stereochemistry of Ketoreductase Domains

Li, Yang, Fiers, William D., Bernard, Steffen M., Smith, Janet L., Aldrich, Courtney C., Fecik, Robert A.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.69 MB

english, 2014

25

Identification of Small Molecules That Protect Pancreatic β Cells against Endoplasmic Reticulum Stress-Induced Cell Death

Tran, Kim, Li, Yu, Duan, Hongliang, Arora, Daleep, Lim, Hui-Ying, Wang, Weidong

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 7.29 MB

english, 2014

26

Chemoproteomics Demonstrates Target Engagement and Exquisite Selectivity of the Clinical Phosphodiesterase 10A Inhibitor MP-10 in Its Native Environment

Schülke, Jan-Philip, McAllister, Laura A., Geoghegan, Kieran F., Parikh, Vinod, Chappie, Thomas A., Verhoest, Patrick R., Schmidt, Christopher J., Johnson, Douglas S., Brandon, Nicholas J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 18.67 MB

english, 2014

27

Exploring a 2-Naphthoic Acid Template for the Structure-Based Design of P2Y 14 Receptor Antagonist Molecular Probes

Kiselev, Evgeny, Barrett, Matthew O., Katritch, Vsevolod, Paoletta, Silvia, Weitzer, Clarissa D., Brown, Kyle A., Hammes, Eva, Yin, Andrew L., Zhao, Qiang, Stevens, Raymond C., Harden, T. Kendall, Jac

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

28

Recoding Aminoacyl-tRNA Synthetases for Synthetic Biology by Rational Protein-RNA Engineering

Hadd, Andrew, Perona, John J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014